Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Frank Heuts"'
Autor:
Chun Jing Wang, Lina Petersone, Natalie M. Edner, Frank Heuts, Vitalijs Ovcinnikovs, Elisavet Ntavli, Alexandros Kogimtzis, Astrid Fabri, Yassin Elfaki, Luke P. Houghton, Ralf J. Hosse, David A. Schubert, Andreas P. Frei, Ellen M. Ross, Lucy S. K. Walker
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Blockade of CD28 costimulation with CTLA-4-Ig/Abatacept is used to dampen effector T cell responses in autoimmune and transplantation settings. However, a significant drawback of this approach is impaired regulatory T cell homeostasis that r
Externí odkaz:
https://doaj.org/article/88fdb72320aa489eb09cc8536ed4b458
Autor:
Chun Jing Wang, Lina Petersone, Natalie M. Edner, Frank Heuts, Vitalijs Ovcinnikovs, Elisavet Ntavli, Alexandros Kogimtzis, Astrid Fabri, Yassin Elfaki, Luke P. Houghton, Ralf J. Hosse, David A. Schubert, Andreas P. Frei, Ellen M. Ross, Lucy S. K. Walker
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/bb4af0f8c0874ff3af8a19e29e105ca1
Autor:
Sreenivasulu B. Reddy, Noemi Nagy, Caroline Rönnberg, Francesca Chiodi, Allan Lugaajju, Frank Heuts, Laszlo Szekely, Mats Wahlgren, Kristina E. M. Persson
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-11 (2021)
Abstract Background Plasmodium falciparum parasites cause malaria and co-exist in humans together with B-cells for long periods of time. Immunity is only achieved after repeated exposure. There has been a lack of methods to mimic the in vivo co-occur
Externí odkaz:
https://doaj.org/article/c83f3f60b71e4c059ee97ab0104e8d42
Autor:
Sreenivasulu B. Reddy, Noemi Nagy, Caroline Rönnberg, Francesca Chiodi, Allan Lugaajju, Frank Heuts, Laszlo Szekely, Mats Wahlgren, Kristina E. M. Persson
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/5474918f89d0480987b03738b102ebf4
Autor:
Lina Petersone, Natalie M. Edner, Vitalijs Ovcinnikovs, Frank Heuts, Ellen M. Ross, Elisavet Ntavli, Chun J. Wang, Lucy S. K. Walker
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Co-ordinated interaction between distinct cell types is a hallmark of successful immune function. A striking example of this is the carefully orchestrated cooperation between helper T cells and B cells that occurs during the initiation and fine-tunin
Externí odkaz:
https://doaj.org/article/a0edfa3c98b64d6e92fe1077110a0a54
Autor:
Frank Heuts, Annemarie Mol
Publikováno v:
Valuation Studies, Vol 1, Iss 2 (2013)
As a contribution to the field of valuation studies this article lays out a number of lessons that follow from an exploratory inquiry into ‘good tomatoes’. We held interviews with tomato experts (developers, growers, sellers, processors, professi
Externí odkaz:
https://doaj.org/article/214e89b4adf44537b5f8279a22299c2a
Autor:
Jonathan Lo, Jan-Hendrik Schroeder, Gordon Beattie, Luke Roberts, Domenico Cozzetto, Omer Omer, Ellen Ross, Frank Heuts, Geraldine Jowett, Emily Read, Zhigang Liu, Hajir Ibraheim, Rocio Castro Seoane, Rami Mohamed, Tamas Korcsmaros, Andrew Cope, Sophie Papa, Joana Neves, Lucy Walker, Richard Jenner, Nick Powell, Graham Lord
The maintenance of intestinal homeostasis is a fundamental process critical for organismal integrity. Sitting at the interface of the gut microbiome and mucosal immunity, adaptive and innate lymphoid populations regulate the balance between commensal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d9030c7d445d0a812d10c9bcb0faad5
https://doi.org/10.21203/rs.3.rs-2729018/v1
https://doi.org/10.21203/rs.3.rs-2729018/v1
Autor:
Natalie M Edner, Elisavet Ntavli, Lina Petersone, Chun Jing Wang, Astrid Fabri, Alexandros Kogimtzis, Vitalijs Ovcinnikovs, Ellen M Ross, Frank Heuts, Yassin Elfaki, Luke P Houghton, Toby Talbot, Amna Sheri, Alexandra Pender, David Chao, Lucy S K Walker
Publikováno v:
Immunotherapy Advances. 3
SummaryEfficacy of checkpoint inhibitor therapies in cancer varies greatly, with some patients showing complete responses while others do not respond and experience progressive disease. We aimed to identify correlates of response and progression foll
Publikováno v:
Sociální studia / Social Studies.
As a contribution to the field of valuation studies this article lays out a number of lessons that follow from an exploratory inquiry into ‘good tomatoes’. We held interviews with tomato experts (developers, growers, sellers, processors, professi
Autor:
Lina Petersone, Chun Jing Wang, Ellen M. Ross, Martin Eichmann, Elisavet Ntavli, Alexandros Kogimtzis, Frank Heuts, Rupert Kenefeck, Natalie M. Edner, Niclas Thomas, Mark Peakman, Roman Baptista, Miranda Rosenthal, Yassin Elfaki, Lutz Jermutus, Lucy S. K. Walker, Vitalijs Ovcinnikovs, Philip Ambery
Publikováno v:
Nature Immunology. 21:1244-1255
Follicular helper T (TFH) cells are implicated in type 1 diabetes (T1D), and their development has been linked to CD28 costimulation. We tested whether TFH cells were decreased by costimulation blockade using the CTLA-4–immunoglobulin (Ig) fusion p