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pro vyhledávání: '"Frank Gielkens"'
Autor:
Loes M. Stevers, Madita Wolter, Graeme W. Carlile, Dwight Macdonald, Luc Richard, Frank Gielkens, John W. Hanrahan, David Y. Thomas, Sai Kumar Chakka, Mark L. Peterson, Helmut Thomas, Luc Brunsveld, Christian Ottmann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Mutations in the chloride channel CFTR that impair plasma membrane insertion and ion transport are the cause of cystic fibrosis. Here, the authors identify a macrocycle that stabilizes the interaction of mutant CFTR with the chaperone-like protein 14
Externí odkaz:
https://doaj.org/article/92fd952667d14a1ba9705d63a6a37de1