A thermodynamically motivated model for stress-fiber reorganization

Autor: Vikram Deshpande, Andrea Vigliotti, Frank Frank Baaijens, William Ronan

Publikováno v: Biomechanics and Modeling in Mechanobiology, 15(4), 761-789. Springer

We present a model for stress-fiber reorganization and the associated contractility that includes both the kinetics of stress-fiber formation and dissociation as well as the kinetics of stress-fiber remodeling. These kinetics are motivated by conside

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04832a83f5eb8f30a59b792bba6cced
https://doi.org/10.1007/s10237-015-0722-9

Heading in the Right Direction: Understanding Cellular Orientation Responses to Complex Biophysical Environments

Autor: Frank Frank Baaijens, Jlv Jos Broers, Carlijn V. C. Bouten, C Chiara Tamiello, Abc Gitta Buskermolen

Publikováno v: Cellular and Molecular Bioengineering
Cellular and Molecular Bioengineering, 9(1), 12-37. Springer Verlag
Cellular and Molecular Bioengineering, 9(1), 12-37. Springer

The aim of cardiovascular regeneration is to mimic the biological and mechanical functioning of tissues. For this it is crucial to recapitulate the in vivo cellular organization, which is the result of controlled cellular orientation. Cellular orient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7857c05c9e573d762335c2dffcf8065f
http://europepmc.org/articles/PMC4746215

In vivo collagen remodeling in the vascular wall of decellularized stented tissue-engineered heart valves

Autor: Petra E. Dijkman, Bart Sanders, Anita Anita Driessen-Mol, Samaneh Ghazanfari, Frank Frank Baaijens, Carlijn V. C. Bouten, Simon P. Hoerstrup

Publikováno v: Tissue engineering. Part A, 21(15-16), 2206-2215. Mary Ann Liebert Inc.
Tissue Engineering. Mary Ann Liebert Inc.

Background: Decellularized tissue-engineered heart valves (TEHVs) are under investigation as alternative for current heart valve prostheses with the potential to rapidly repopulate with cells within the body. Ideally, these valves are stented for tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ce26218f48d3de9d5364c5c00983fe
https://doi.org/10.1089/ten.tea.2014.0417

Competition between cap and basal actin fiber orientation in cells subjected to contact guidance and cyclic strain

Autor: Carlijn V. C. Bouten, Frank Frank Baaijens, C Chiara Tamiello

Publikováno v: Scientific Reports, 5:8752, 1-10. Nature Publishing Group
Scientific Reports

In vivo, adhesive cells continuously respond to a complex range of physical cues coming from the surrounding microenvironment by remodeling their cytoskeleton. Topographical and mechanical cues applied separately have been shown to affect the orienta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849c8ac1abb6ae8b79a44a8a58835668
https://doi.org/10.1038/srep08752

Compressive mechanical properties of atherosclerotic plaques-Indentation test to characterise the local anisotropic behaviour

Autor: C-K Chen-Ket Chai, Lambert Speelman, Cwj Cees Oomens, Frank Frank Baaijens

Publikováno v: Journal of Biomechanics, 47(4), 784-792. Elsevier

Accurate material models and associated parameters of atherosclerotic plaques are crucial for reliable biomechanical plaque prediction models. These biomechanical models have the potential to increase our understanding of plaque progression and failu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5caf79ca38f82703c27d077969342cd8
https://doi.org/10.1016/j.jbiomech.2014.01.018