Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Frank D. Bohmer"'
Autor:
Gerald M. McMahon, Frank D. Bohmer, Harald App, Aviv Gazit, Jefferey Chen, Alexander Levitzki
Publikováno v:
Journal of Medicinal Chemistry. 39:2170-2177
A series of 3-indoleacrylonitrile tyrphostins, 2-chloro-3-phenylquinolines, and 3-arylquinoxalines were prepared and tested for inhibition of platelet-derived growth factor receptor tyrosine kinase (PDGF-RTK) activity. The potency of the inhibitors w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d30728766c1982ee166b1c385143c5d
https://doi.org/10.1021/jm950727b
https://doi.org/10.1021/jm950727b
Autor:
Muhammed Burak Demircan, Peter C. Mgbecheta, Anne Kresinsky, Tina M. Schnoeder, Katrin Schröder, Florian H. Heidel, Frank D. Böhmer
Publikováno v:
Antioxidants, Vol 11, Iss 3, p 513 (2022)
Acute myeloid leukemia (AML) cells harbor elevated levels of reactive oxygen species (ROS), which promote cell proliferation and cause oxidative stress. Therefore, the inhibition of ROS formation or elevation beyond a toxic level have been considered
Externí odkaz:
https://doaj.org/article/76f0fad3945d48f7882ce02f3570f99d
Autor:
Janine Krüger, Sebastian Brachs, Manuela Trappiel, Ulrich Kintscher, Heike Meyborg, Ernst Wellnhofer, Christa Thöne-Reineke, Philipp Stawowy, Arne Östman, Andreas L. Birkenfeld, Frank D. Böhmer, Kai Kappert
Publikováno v:
Molecular Metabolism, Vol 4, Iss 4, Pp 325-336 (2015)
Objective: Insulin resistance can be triggered by enhanced dephosphorylation of the insulin receptor or downstream components in the insulin signaling cascade through protein tyrosine phosphatases (PTPs). Downregulating density-enhanced phosphatase-1
Externí odkaz:
https://doaj.org/article/2917854160704f93a91cd9e0cd82d0eb