Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Frank Czauderna"'
Autor:
Lyubomir T. Vassilev, Andree Blaukat, Frank T. Zenke, Frank Czauderna, Qing Sun, Yan Lan, Bo Marelli, Jin Qi, Guozhong Qin, Huakui Yu, Adam S. Lazorchak, Chunxiao Xu, Yige Guo, Li-Ya Chiu, Michael I. Carr
Supplementary Figure from DNA-PK Inhibitor Peposertib Amplifies Radiation-Induced Inflammatory Micronucleation and Enhances TGFβ/PD-L1 Targeted Cancer Immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c2acc1536fcc02da749b1d44d21c68
https://doi.org/10.1158/1541-7786.22528214.v1
https://doi.org/10.1158/1541-7786.22528214.v1
Autor:
Lyubomir T. Vassilev, Andree Blaukat, Frank T. Zenke, Michael I. Carr, Frank Czauderna, Xiaohong Liu, Yige Guo, Qing Sun
Text file with figure legends and two references cited in Fig S6 legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0029fe928fe2ade375e1222efc5fa0
https://doi.org/10.1158/1541-7786.22512480
https://doi.org/10.1158/1541-7786.22512480
Autor:
Lyubomir T. Vassilev, Andree Blaukat, Frank T. Zenke, Michael I. Carr, Frank Czauderna, Xiaohong Liu, Yige Guo, Qing Sun
Figure S1. Inhibition of DNA-PK activity by M3814 overactivates the p53 response to radiation-induced DSBs. Figure S2. The inactive M3814 enantiomer, M3814R, does not enhance the p53 response to IR and M3814. Figure S3. IR plus M3814 treatment induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb092786ed66bf408fcc5a5d70db59a
https://doi.org/10.1158/1541-7786.22512477.v1
https://doi.org/10.1158/1541-7786.22512477.v1
Autor:
Lyubomir T. Vassilev, Andree Blaukat, Frank T. Zenke, Michael I. Carr, Frank Czauderna, Xiaohong Liu, Yige Guo, Qing Sun
SI Fig. 7 with 4 embedded videos. Please click on arrow to see videos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5488f03e7ceb45f6a3cc71a14ee5453b
https://doi.org/10.1158/1541-7786.22512486
https://doi.org/10.1158/1541-7786.22512486
Autor:
Lyubomir T. Vassilev, Andree Blaukat, Frank T. Zenke, Michael I. Carr, Frank Czauderna, Xiaohong Liu, Yige Guo, Qing Sun
Inhibition of DNA double-strand break (DSB) repair in cancer cells has been proposed as a new therapeutic strategy for potentiating the anticancer effects of radiotherapy. M3814 is a novel, selective pharmacologic inhibitor of the serine/threonine ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c2da83e39f9174938502d53dc098a38
https://doi.org/10.1158/1541-7786.c.6540252.v1
https://doi.org/10.1158/1541-7786.c.6540252.v1
Autor:
Lyubomir T. Vassilev, Andree Blaukat, Frank T. Zenke, Michael I. Carr, Frank Czauderna, Xiaohong Liu, Yige Guo, Qing Sun
Fig.S4 with embedded videos in panel B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f87c16c40374bb3ed7758feb012806
https://doi.org/10.1158/1541-7786.22512483
https://doi.org/10.1158/1541-7786.22512483
Autor:
Lyubomir T. Vassilev, Andree Blaukat, Frank T. Zenke, Frank Czauderna, Qing Sun, Yan Lan, Bo Marelli, Jin Qi, Guozhong Qin, Huakui Yu, Adam S. Lazorchak, Chunxiao Xu, Yige Guo, Li-Ya Chiu, Michael I. Carr
Radiotherapy is the most widely used cancer treatment and improvements in its efficacy and safety are highly sought-after. Peposertib (also known as M3814), a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor, effectively suppresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0844dbdfe98c4fcd7d969a6bceba5225
https://doi.org/10.1158/1541-7786.c.6545648.v1
https://doi.org/10.1158/1541-7786.c.6545648.v1
Autor:
Michael I. Carr, Li-Ya Chiu, Yige Guo, Chunxiao Xu, Adam S. Lazorchak, Huakui Yu, Guozhong Qin, Jin Qi, Bo Marelli, Yan Lan, Qing Sun, Frank Czauderna, Frank T. Zenke, Andree Blaukat, Lyubomir T. Vassilev
Publikováno v:
Molecular Cancer Research. 20:568-582
Radiotherapy is the most widely used cancer treatment and improvements in its efficacy and safety are highly sought-after. Peposertib (also known as M3814), a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor, effectively suppresse
Autor:
Frank Zenke, Frank Czauderna, Yige Guo, Qing Sun, Michael I. Carr, Andree Blaukat, Lyubomir T. Vassilev, Xiaohong Liu
Publikováno v:
Molecular Cancer Research. 17:2457-2468
Inhibition of DNA double-strand break (DSB) repair in cancer cells has been proposed as a new therapeutic strategy for potentiating the anticancer effects of radiotherapy. M3814 is a novel, selective pharmacologic inhibitor of the serine/threonine ki
Autor:
Andrzej Gondela, Marcin Leś, Maciej Mikulski, Łukasz Włoszczak, Frank Becker, Kamila Olech, Shivapriya Ramaswamy, Marcin Król, Henryk Pawlik, Christian Herhaus, Jose Alvarez, Joanna Szczęśniak, Heike Schilke, Paulina Niedziejko, Lindsey Crowley, Roberta Ferretti, Mireille Krier, Pamela Wahra, Pia Böpple, Timo Heinrich, Justyna Martyka, Ewa Sitek, Karol Zuchowicz, Ada Sala-Hojman, Anna Bartosik, Stefano Minguzzi, Łukasz Dudek, Frank Czauderna, Mateusz Nowak, Ansgar Wegener, Michal Galezowski, Carl Petersson, Sven Jäckel
Publikováno v:
Journal of medicinal chemistry. 64(16)
Due to increased lactate production during glucose metabolism, tumor cells heavily rely on efficient lactate transport to avoid intracellular lactate accumulation and acidification. Monocarboxylate transporter 4 (MCT4/SLC16A3) is a lactate transporte