Zobrazeno 1 - 10
of 295
pro vyhledávání: '"Frank C Schroeder"'
Autor:
Olga Ponomarova, Hefei Zhang, Xuhang Li, Shivani Nanda, Thomas B Leland, Bennett W Fox, Alyxandra N Starbard, Gabrielle E Giese, Frank C Schroeder, L Safak Yilmaz, Albertha J M Walhout
Publikováno v:
PLoS Biology, Vol 21, Iss 4, p e3002057 (2023)
In humans, mutations in D-2-hydroxyglutarate (D-2HG) dehydrogenase (D2HGDH) result in D-2HG accumulation, delayed development, seizures, and ataxia. While the mechanisms of 2HG-associated diseases have been studied extensively, the endogenous metabol
Externí odkaz:
https://doaj.org/article/8eb43474349b438fb9ef2191ac40b72a
Publikováno v:
eLife, Vol 10 (2021)
Foraging animals have to locate food sources that are usually patchily distributed and subject to competition. Deciding when to leave a food patch is challenging and requires the animal to integrate information about food availability with cues signa
Externí odkaz:
https://doaj.org/article/562a921d7db04fb4a193d08c0f1eed0e
Autor:
Henry H Le, Chester JJ Wrobel, Sarah M Cohen, Jingfang Yu, Heenam Park, Maximilian J Helf, Brian J Curtis, Joseph C Kruempel, Pedro Reis Rodrigues, Patrick J Hu, Paul W Sternberg, Frank C Schroeder
Publikováno v:
eLife, Vol 9 (2020)
Signaling molecules derived from attachment of diverse metabolic building blocks to ascarosides play a central role in the life history of C. elegans and other nematodes; however, many aspects of their biogenesis remain unclear. Using comparative met
Externí odkaz:
https://doaj.org/article/ad5cace3227746cc9ccec0c24be6f529
Autor:
Aude D Bouagnon, Lin Lin, Shubhi Srivastava, Chung-Chih Liu, Oishika Panda, Frank C Schroeder, Supriya Srinivasan, Kaveh Ashrafi
Publikováno v:
PLoS Biology, Vol 17, Iss 12, p e3000242 (2019)
The ability to coordinate behavioral responses with metabolic status is fundamental to the maintenance of energy homeostasis. In numerous species including Caenorhabditis elegans and mammals, neural serotonin signaling regulates a range of food-relat
Externí odkaz:
https://doaj.org/article/d8903361c0df4454997764a6cd0684c9
Autor:
Stefan Zdraljevic, Bennett William Fox, Christine Strand, Oishika Panda, Francisco J Tenjo, Shannon C Brady, Tim A Crombie, John G Doench, Frank C Schroeder, Erik C Andersen
Publikováno v:
eLife, Vol 8 (2019)
We find that variation in the dbt-1 gene underlies natural differences in Caenorhabditis elegans responses to the toxin arsenic. This gene encodes the E2 subunit of the branched-chain α-keto acid dehydrogenase (BCKDH) complex, a core component of br
Externí odkaz:
https://doaj.org/article/399d48554fb541b99853ddb37c526e13
Autor:
Rosalind Hussey, Jon Stieglitz, Jaleh Mesgarzadeh, Tiffany T Locke, Ying K Zhang, Frank C Schroeder, Supriya Srinivasan
Publikováno v:
PLoS Genetics, Vol 13, Iss 5, p e1006806 (2017)
It is now established that the central nervous system plays an important role in regulating whole body metabolism and energy balance. However, the extent to which sensory systems relay environmental information to modulate metabolic events in periphe
Externí odkaz:
https://doaj.org/article/deb18dd8de53439c93d1d5b5ab9440e3
Autor:
Andreas H Ludewig, Clotilde Gimond, Joshua C Judkins, Staci Thornton, Dania C Pulido, Robert J Micikas, Frank Döring, Adam Antebi, Christian Braendle, Frank C Schroeder
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006717 (2017)
Environmental conditions experienced during animal development are thought to have sustained impact on maturation and adult lifespan. Here we show that in the model organism C. elegans developmental rate and adult lifespan depend on larval population
Externí odkaz:
https://doaj.org/article/ae12795da473417daaad597e7fbe2665
Autor:
Yen-Ping Hsueh, Matthew R Gronquist, Erich M Schwarz, Ravi David Nath, Ching-Han Lee, Shalha Gharib, Frank C Schroeder, Paul W Sternberg
Publikováno v:
eLife, Vol 6 (2017)
To study the molecular basis for predator-prey coevolution, we investigated how Caenorhabditis elegans responds to the predatory fungus Arthrobotrys oligospora. C. elegans and other nematodes were attracted to volatile compounds produced by A. oligos
Externí odkaz:
https://doaj.org/article/7439723812c244babd52db7fd73fa35e
Autor:
Agata Szczepańska, Katarzyna Olek, Klaudia Kołodziejska, Jingfang Yu, Abdulrahman Tudu Ibrahim, Laura Adamkiewicz, Frank C. Schroeder, Wojciech Pokrzywa, Michał Turek
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Extracellular vesicles (EVs) are integral to numerous biological processes, yet it is unclear how environmental factors or interactions among individuals within a population affect EV-regulated systems. In Caenorhabditis elegans, the evoluti
Externí odkaz:
https://doaj.org/article/a9781c1c4b834f6f8b0f7f3af2e1440c
Autor:
Bennett W. Fox, Maximilian J. Helf, Russell N. Burkhardt, Alexander B. Artyukhin, Brian J. Curtis, Diana Fajardo Palomino, Allen F. Schroeder, Amaresh Chaturbedi, Arnaud Tauffenberger, Chester J. J. Wrobel, Ying K. Zhang, Siu Sylvia Lee, Frank C. Schroeder
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Fatty acid desaturation is central to metazoan lipid metabolism and provides building blocks of membrane lipids and precursors of diverse signaling molecules. Nutritional conditions and associated microbiota regulate desaturase expression, b
Externí odkaz:
https://doaj.org/article/c560af47fb5e4536a8660e27f05de7c2