Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Frank C Deguire"'
Autor:
Daniel G.P. Turner, Leonid Tyan, Frank C. DeGuire, Roman Y. Medvedev, Sami J. Stroebel, Di Lang, Alexey V. Glukhov
Publikováno v:
Biophys J
Caveola membrane structures harbor mechanosensitive chloride channels (MCCs; including chloride channel 2, chloride channel 3, and SWELL1, also known as LRRC8A) that form a swelling-activated chloride current (I(Cl,swell)) and play an important role
Publikováno v:
Circulation Research. 129
Background: Caveolae membrane structures harbor mechanosensitive chloride channels (MCCs) which form a swelling-activated chloride current ( I Cl,swell ) and play an important role in cell volume regulation and mechano-electrical signal transduction.
Publikováno v:
Circulation Research. 129
Background: Atrial fibrillation (AF) often occurs during hypertension and is associated with an increase in cardiomyocyte stretch. Mechanism of ectopic beats, that trigger AF, has been linked to Ca 2+ mishandling and leaky hyperphosphorylated ryanodi
Autor:
Alexey V. Glukhov, Frank C Deguire, Roman Y Medvedev, Lucas N. Ratajczyk, Di Lang, Alexander R Vasquez
Publikováno v:
Circulation Research. 127
Background: In cardiac myocytes, efficient and synchronous excitation-contraction coupling (ECC) occurs through a specialized network of membrane invaginations called transverse-axial tubule system (TATS). In contrast to an extensive TATS in ventricu
Publikováno v:
Circulation Research. 127
Caveolae are small (50-100nm) membrane invaginations formed by caveolin proteins enriched with cholesterol and lipids. Caveolae play a crucial role in mechanoprotection and mechano-electrical transduction by buffering membrane tension and facilitatin