Zobrazeno 1 - 10
of 295
pro vyhledávání: '"Frank C, Schroeder"'
Autor:
Agata Szczepańska, Katarzyna Olek, Klaudia Kołodziejska, Jingfang Yu, Abdulrahman Tudu Ibrahim, Laura Adamkiewicz, Frank C. Schroeder, Wojciech Pokrzywa, Michał Turek
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Extracellular vesicles (EVs) are integral to numerous biological processes, yet it is unclear how environmental factors or interactions among individuals within a population affect EV-regulated systems. In Caenorhabditis elegans, the evoluti
Externí odkaz:
https://doaj.org/article/a9781c1c4b834f6f8b0f7f3af2e1440c
Autor:
Bennett W. Fox, Maximilian J. Helf, Russell N. Burkhardt, Alexander B. Artyukhin, Brian J. Curtis, Diana Fajardo Palomino, Allen F. Schroeder, Amaresh Chaturbedi, Arnaud Tauffenberger, Chester J. J. Wrobel, Ying K. Zhang, Siu Sylvia Lee, Frank C. Schroeder
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Fatty acid desaturation is central to metazoan lipid metabolism and provides building blocks of membrane lipids and precursors of diverse signaling molecules. Nutritional conditions and associated microbiota regulate desaturase expression, b
Externí odkaz:
https://doaj.org/article/c560af47fb5e4536a8660e27f05de7c2
Autor:
Javier Marquina-Solis, Likui Feng, Elke Vandewyer, Isabel Beets, Josh Hawk, Daniel A. Colón-Ramos, Jingfang Yu, Bennett W. Fox, Frank C. Schroeder, Cornelia I. Bargmann
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114042- (2024)
Summary: Pathogenic infection elicits behaviors that promote recovery and survival of the host. After exposure to the pathogenic bacterium Pseudomonas aeruginosa PA14, the nematode Caenorhabditis elegans modifies its sensory preferences to avoid the
Externí odkaz:
https://doaj.org/article/380310b1b4e44327aeb4afe0193dc3b1
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 113996- (2024)
Summary: Physiological dysfunction confers negative valence to coincidental sensory cues to induce the formation of aversive associative memory. How peripheral tissue stress engages neuromodulatory mechanisms to form aversive memory is poorly underst
Externí odkaz:
https://doaj.org/article/3652b80e347649bfbb892543f3d328bf
Autor:
Bennett W. Fox, Maximilian J. Helf, Russell N. Burkhardt, Alexander B. Artyukhin, Brian J. Curtis, Diana Fajardo Palomino, Allen F. Schroeder, Amaresh Chaturbedi, Arnaud Tauffenberger, Chester J. J. Wrobel, Ying K. Zhang, Siu Sylvia Lee, Frank C. Schroeder
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/4b532cc862454011b496301edad55304
Autor:
Wiebke Obermann, Mohammad Farhan Darin Azri, Leonie Konopka, Nina Schmidt, Francesca Magari, Julian Sherman, Liliana M. R. Silva, Carlos Hermosilla, Andreas H. Ludewig, Hicham Houhou, Simone Haeberlein, Mona Yiting Luo, Irina Häcker, Marc F. Schetelig, Christoph G. Grevelding, Frank C. Schroeder, Gilbert Sei Kung Lau, Anja Taubert, Ana Rodriguez, Andreas Heine, Tiong Chia Yeo, Arnold Grünweller, Gaspar Taroncher-Oldenburg
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Inhibition of eukaryotic initiation factor 4A has been proposed as a strategy to fight pathogens. Rocaglates exhibit the highest specificities among eIF4A inhibitors, but their anti-pathogenic potential has not been comprehensively assessed
Externí odkaz:
https://doaj.org/article/8922ae7cbaff49e69d1bb970b63c9468
Autor:
Russell N. Burkhardt, Alexander B. Artyukhin, Erin Z. Aprison, Brian J. Curtis, Bennett W. Fox, Andreas H. Ludewig, Diana Fajardo Palomino, Jintao Luo, Amaresh Chaturbedi, Oishika Panda, Chester J. J. Wrobel, Victor Baumann, Douglas S. Portman, Siu Sylvia Lee, Ilya Ruvinsky, Frank C. Schroeder
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Biological sex affects all aspects of animal physiology. Using the model C. elegans, the authors show that metabolomes are highly sex-specific and include a vast space of yet unidentified metabolites that may control development and lifespan.
Externí odkaz:
https://doaj.org/article/ee59faf2849443c2ad2e5ad357aac4f5
Autor:
Tae Hyung Won, Jin Woo Bok, Nischala Nadig, Nandhitha Venkatesh, Grant Nickles, Claudio Greco, Fang Yun Lim, Jennifer B. González, B. Gillian Turgeon, Nancy P. Keller, Frank C. Schroeder
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The genomes of filamentous fungi, such as Aspergillus, include many biosynthetic gene clusters of unknown function. Here, the authors show that copper starvation induces expression of an enzyme that generates a valine-derived isocyanide participating
Externí odkaz:
https://doaj.org/article/61108be1a7c646178d0381c77202ef91
Autor:
Olga Ponomarova, Hefei Zhang, Xuhang Li, Shivani Nanda, Thomas B Leland, Bennett W Fox, Alyxandra N Starbard, Gabrielle E Giese, Frank C Schroeder, L Safak Yilmaz, Albertha J M Walhout
Publikováno v:
PLoS Biology, Vol 21, Iss 4, p e3002057 (2023)
In humans, mutations in D-2-hydroxyglutarate (D-2HG) dehydrogenase (D2HGDH) result in D-2HG accumulation, delayed development, seizures, and ataxia. While the mechanisms of 2HG-associated diseases have been studied extensively, the endogenous metabol
Externí odkaz:
https://doaj.org/article/8eb43474349b438fb9ef2191ac40b72a
Autor:
Maximilian J. Helf, Bennett W. Fox, Alexander B. Artyukhin, Ying K. Zhang, Frank C. Schroeder
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Untargeted mass spectrometry-based metabolomics can reveal new biochemistry, but data analysis is challenging. Here, the authors develop Metaboseek, an open-source software that facilitates metabolite discovery, and apply it to characterize fatty aci
Externí odkaz:
https://doaj.org/article/29a2d5b9d31849268df501570d83c192