Zobrazeno 1 - 10
of 511
pro vyhledávání: '"Frank Buttgereit"'
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 4, Pp 151455- (2024)
Rheumatoid arthritis (RA) and osteoarthritis (OA) are prevalent inflammatory joint diseases characterized by synovitis, cartilage, and bone destruction. Fibroblast-like synoviocytes (FLSs) of the synovial membrane are a decisive factor in arthritis,
Externí odkaz:
https://doaj.org/article/8b07098b82da4b5e870f61bd8a880475
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Osteoarthritis (OA) is the most common form of arthritis, characterized by osteophyte formation, cartilage degradation, and structural and cellular alterations of the synovial membrane. Activated fibroblast-like synoviocytes (FLS) of the synovial mem
Externí odkaz:
https://doaj.org/article/f61fb2689d3d46d88aefb8419394c88d
Autor:
Wolfgang A. Schmidt, Bhaskar Dasgupta, Jennifer Sloane, Angeliki Giannelou, Yuqing Xu, Sebastian H. Unizony, Sarah L. Mackie, Miguel A. Gonzalez-Gay, Robert Spiera, Kenneth J. Warrington, Peter M. Villiger, Michael C. Nivens, Bolanle Akinlade, Yong Lin, Frank Buttgereit, John H. Stone
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-16 (2023)
Abstract Background Giant cell arteritis (GCA) is primarily treated with glucocorticoids (GCs), which have substantial toxicity. Tocilizumab, an interleukin-6-receptor inhibitor (IL-6Ri), showed beneficial effects in GCA, leading to its approval. Thi
Externí odkaz:
https://doaj.org/article/4519641ec60d4627b6d5c6d36c1bb6ac
Autor:
Tazio Maleitzke, Edgar Wiebe, Dörte Huscher, Cornelia M. Spies, Jinwen Tu, Timo Gaber, Yu Zheng, Frank Buttgereit, Markus J. Seibel, Hong Zhou
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Background Disruption of glucocorticoid (GC) signaling in osteoblasts results in a marked attenuation of acute antibody-induced arthritis. The role of endogenous GCs in chronic inflammatory arthritis is however not fully understood. Here, we
Externí odkaz:
https://doaj.org/article/39e36f88625d46b9843de9f0a12cf76c
Autor:
Andriko Palmowski, Zhivana Boyadzhieva, Sabrina M. Nielsen, Burkhard Muche, Sandra Hermann, Maarten Boers, Henning Bliddal, Robin Christensen, Edgar Wiebe, Frank Buttgereit
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-9 (2023)
Abstract Background It is unclear whether sex or age modify the association of glucocorticoid (GC) use with reduced bone mineral density (BMD) in patients with rheumatoid arthritis (RA). Methods We studied cross-sectional data of RA patients with cur
Externí odkaz:
https://doaj.org/article/259c1c37d9b447ca833437509195a982
Autor:
Angelique Wolter, Christian H. Bucher, Sebastian Kurmies, Viktoria Schreiner, Frank Konietschke, Katharina Hohlbaum, Robert Klopfleisch, Max Löhning, Christa Thöne-Reineke, Frank Buttgereit, Jörg Huwyler, Paulin Jirkof, Anna E. Rapp, Annemarie Lang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Adequate pain management is essential for ethical and scientific reasons in animal experiments and should completely cover the period of expected pain without the need for frequent re-application. However, current depot formulations of Bupre
Externí odkaz:
https://doaj.org/article/a3a6e5e452f34a039c52216254fc8390
Autor:
Lisa Christ, Andrea D. Gloor, Florian Kollert, Timo Gaber, Frank Buttgereit, Stephan Reichenbach, Peter M. Villiger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectiveProteome analyses in patients with newly diagnosed, untreated giant cell arteritis (GCA) have not been reported previously, nor are changes of protein expression upon treatment with glucocorticoids (GC) and/or tocilizumab (TCZ) known. The GU
Externí odkaz:
https://doaj.org/article/ab22f1dff0334cf28d896675155bdf8e
Autor:
Sabine Wiegmann, Gabriele Armbrecht, Diana Borucki, Bjoern Buehring, Frank Buttgereit, Christian Detzer, Désirée Schaumburg, Kim Nikola Zeiner, Roswitha Dietzel
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-21 (2022)
Abstract Background Postural control is associated with fall risk. Patients with rheumatoid arthritis (RA) have a higher risk to fall than healthy subjects. The objective of this study was to identify associations between variables of postural contro
Externí odkaz:
https://doaj.org/article/fb44a728e58a451792f81a6edf149720
Autor:
Sabine Wiegmann, Gabriele Armbrecht, Diana Borucki, Bjoern Buehring, Frank Buttgereit, Christian Detzer, Désirée Schaumburg, Kim Nikola Zeiner, Roswitha Dietzel
Publikováno v:
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background Patients with rheumatoid arthritis (RA) are at increased risk of falls and fractures. Sarcopenia occurs more frequently in RA patients due to the inflammatory processes. Early diagnosis and prevention programmes are essential to a
Externí odkaz:
https://doaj.org/article/46430b7365b54fd79f8310deb5e54a7c
Autor:
Frank Buttgereit, Désireé Schaumburg, Roswitha Dietzel, Sabine Wiegmann, Diana Borucki, Christian Detzer, Kim Nikola Zeiner, Gabriele Armbrecht
Publikováno v:
RMD Open, Vol 8, Iss 2 (2022)
Objective In rheumatoid arthritis (RA), chronic inflammation can enhance the development of sarcopenia with a depletion of muscle mass, strength and performance. Currently, a consensus definition for sarcopenia and solid results for the prevalence of
Externí odkaz:
https://doaj.org/article/191c7192db9c4766bc3fbfc433c918a1