Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Frank Bollig"'
Autor:
Astrid Behnert, Marvin J Fritzler, Beina Teng, Meifeng Zhang, Frank Bollig, Hermann Haller, Andrej Skoberne, Michael Mahler, Mario Schiffer
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61669 (2013)
The phospholipase A2 receptor (PLA2R) was recently discovered as a target autoantigen in patients with idiopathic membranous nephropathy (IMN). Published evidence suggests that the autoantibodies directed towards a conformation dependent epitope are
Externí odkaz:
https://doaj.org/article/20e17bc829c645a59d5b23f769528b16
Autor:
Sharon Ashworth, Beina Teng, Jessica Kaufeld, Emily Miller, Irini Tossidou, Christoph Englert, Frank Bollig, Lynne Staggs, Ian S D Roberts, Joon-Keun Park, Hermann Haller, Mario Schiffer
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12626 (2010)
BACKGROUND: Podocytes are highly specialized epithelial cells on the visceral side of the glomerulus. Their interdigitating primary and secondary foot processes contain an actin based contractile apparatus that can adjust to changes in the glomerular
Externí odkaz:
https://doaj.org/article/1d197e41d627485087b1d5bdf9a70c5d
Autor:
Lynne Staggs, Torsten Kirsch, Frank Bollig, Hermann Haller, Dirk M. Hentschel, Patricia Schroder, Jessica Kaufeld, Ron Korstanje, Michaela Beese, Mario Schiffer, Lisa Boehme
Publikováno v:
Scopus-Elsevier
Hypertension is one of the major risk factors for chronic kidney disease. Using quantitative trait loci analysis, we identified the gene of the F-BAR protein NOSTRIN in the center of an overlapping region in rat and human quantitative trait loci that
Autor:
Karlhans Endlich, Frank Bollig, Antje Blumenthal, Andreas Greinacher, Nicole Endlich, Tobias Müller, Susanne Hradetzky, Elisabeth Rumpel, Henny Wegner
Publikováno v:
Kidney International. 80:1055-1063
Mutations in the MYH9 gene, coding for the non-muscle myosin heavy chain IIA (NMHC-IIA), are responsible for syndromes characterized by macrothrombocytopenia associated with deafness, cataracts, and severe glomerular disease. Electron microscopy of r
Autor:
Rebecca A. Wingert, Hao Zhu, Dongdong Ma, Gordana Djordjevic, Natasha Arora, Rahul C. Deo, Neil A. Hukriede, Chad A. Cowan, Teresa M. Holm, Benjamin R. Lichman, Christoph Englert, Cuong Q. Diep, Frank Bollig, Fumihito Ono, Richard W. Naylor, Takanori Ikenaga, Alan J. Davidson, Robert I. Handin
Publikováno v:
Nature. 470:95-100
Loss of kidney function underlies many renal diseases. Mammals can partly repair their nephrons (the functional units of the kidney), but cannot form new ones. By contrast, fish add nephrons throughout their lifespan and regenerate nephrons de novo a
Autor:
Frank Hänel, Frank Bollig, Dagmar Kruspe, Andreas Kispert, Mark-Oliver Trowe, Birgit Besenbeck, Kathrin Landgraf, Christoph Englert, Christina Ebert
Publikováno v:
Molecular and cellular biology, 30(24): 5764-5775
The human EYA1 gene is an ortholog of the fruit fly eyes absent gene (eya), which was identified as a regulator of compound eye development. In contrast to the single eya gene found in Drosophila melanogaster, mammals possess four Eya paralogs, desig
Publikováno v:
American Journal of Physiology-Renal Physiology. 299:F1040-F1047
The zebrafish is a valuable vertebrate model for kidney research. The majority of previous studies focused on the zebrafish pronephros, which comprises only two nephrons and is structurally simpler than the mesonephros of adult fish and the metanephr
Autor:
Wonhee Hur, Frank Bollig, Ho-Shik Kim, Seung Kew Yoon, Jirouta Kitagaki, Karim Malik, Alan O. Perantoni, Miguel Rivera, Yun-Ping Wu, Christoph Englert, Jik Young Park, Nathan J. Whye, Sean Bong Lee, Myoung Shin Kim, Daphne W. Bell
Publikováno v:
Journal of Biological Chemistry. 285:14585-14593
Mammalian kidney development requires the functions of the Wilms tumor gene WT1 and the WNT/beta-catenin signaling pathway. Recent studies have shown that WT1 negatively regulates WNT/beta-catenin signaling, but the molecular mechanisms by which WT1
Autor:
Christoph Englert, Matthias Schäfer, Birgit Perner, Christoph Winkler, Frank Bollig, Manfred Schartl, Christina Hartung, Jean-Nicolas Volff, Rebecca Mehringer
Publikováno v:
Developmental Dynamics. 235:554-561
The Wilms' tumor suppressor gene wt1 encodes a zinc-finger transcription factor that plays an important role in the development of the mammalian genitourinary system. Mutations in WT1 in humans lead to anomalies of kidney and gonad development and ca
Autor:
Matthias Gaestel, Helmut Holtmann, Frank Bollig, Susanne Kostka, Reinhard Winzen, Klaus Resch
Publikováno v:
Biochemical and Biophysical Research Communications. 301:665-670
An important determinant for the expression level of cytokines and proto-oncogenes is the rate of degradation of their mRNAs. AU-rich sequence elements (AREs) in the 3(') untranslated regions have been found to impose rapid decay of these mRNAs. ARE-