Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Frank Blaeser"'
Autor:
Frank Blaeser, I-Chen Peng, Zhen Chen, Traci L. Marin, Pang-Hung Hsu, David A. Johnson, Christian Lytle, John Y.-J. Shyy, Xiaopei Cui, Mei-I Su, Wei Sun, Songqin Pan, Talal A. Chatila, Ying-Shiuan Li
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 302:E1560-E1568
Glucagon is important for regulating lipid metabolism in part through its inhibition of fatty acid synthesis in adipocytes. Acetyl-CoA carboxylase 1 (ACC1) is the rate-limiting enzyme for fatty acid synthesis. Glucagon has been proposed to activate c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d40fa982b91a4b44e64a5ef6c5f885c
https://doi.org/10.1152/ajpendo.00504.2011
https://doi.org/10.1152/ajpendo.00504.2011
Autor:
Mio Nonaka, Yoshiaki Tagawa, Frank Blaeser, Aki Adachi-Morishima, Tatsuo Mano, Haruhiko Bito, Hidenobu Mizuno, Natsumi Ageta-Ishihara, Hajime Fujii, Satoshi Kamijo, Talal A. Chatila, Hiroyuki Okuno, Sayaka Takemoto-Kimura, Tomoo Hirano, Kanzo Suzuki
Publikováno v:
The Journal of Neuroscience. 29:13720-13729
Ca2+signaling plays important roles during both axonal and dendritic growth. Yet whether and how Ca2+rises may trigger and contribute to the development of long-range cortical connections remains mostly unknown. Here, we demonstrate that two separate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a089518c224c930f204cec597b77def3
https://doi.org/10.1523/jneurosci.3018-09.2009
https://doi.org/10.1523/jneurosci.3018-09.2009
Autor:
Nga Truong, Gregory A. Storch, Jessica Whitlock, Karen Siegrist, Talal A. Chatila, Richard S. Buller, Frank Blaeser, Michael Kelly
Publikováno v:
Clinical Immunology. 117:231-237
Parvovirus B19-induced chronic anemia has been associated with failure to mount an effective neutralizing antibody response. We describe an adolescent male with a 13-year history of parvovirus B19-induced anemia as the primary manifestation of X-link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2cc3badbd41b8d53418a029545c1edb
https://doi.org/10.1016/j.clim.2005.08.005
https://doi.org/10.1016/j.clim.2005.08.005
Autor:
Nga Ho, Frank Blaeser, Vidya Raman, Fatma Dedeoglu, Raif S. Geha, Paul J. Bryce, Talal A. Chatila, Hans C. Oettgen, Debra D. Donaldson
Publikováno v:
The Journal of Experimental Medicine
The insulin/interleukin-4 (IL-4) receptor (I4R) motif mediates the association of insulin receptor substrate (IRS)-2 with the interleukin-4 (IL-4)Rα chain and transduces mitogenic signals in response to IL-4. Its physiological functions were analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24efe54d956b807491954e648c64ed4
https://doi.org/10.1084/jem.20030471
https://doi.org/10.1084/jem.20030471
Autor:
Frank Blaeser, Nga Ho, Anne M. Bowcock, Howard M. Lederman, Cindy Helms, Constantine Voulgaropoulos, Talal A. Chatila
Publikováno v:
Journal of Clinical Investigation. 106:R75-R81
X-linked autoimmunity–allergic disregulation syndrome (XLAAD) is an X-linked recessive immunological disorder characterized by multisystem autoimmunity, particularly early-onset type 1 diabetes mellitus, associated with manifestations of severe ato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7405010946aa3fb0e27efab182651591
https://doi.org/10.1172/jci11679
https://doi.org/10.1172/jci11679
Publikováno v:
Journal of Biological Chemistry. 275:197-209
Ca(2+) induction of a subset of cellular and viral immediate-early activation genes in lymphocytes has been previously mapped to response elements recognized by the MEF2 family of transcription factors. Here, we demonstrate that Ca(2+) activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19460dc1d9bb41567f5427c1cc823a9
https://doi.org/10.1074/jbc.275.1.197
https://doi.org/10.1074/jbc.275.1.197
Autor:
Frank Blaeser, Matthew J. Sanders, Shanelle Ko, Michael S. Fanselow, Min Zhuo, David F. Wozniak, Talal A. Chatila, Nga Truong, Long Jun Wu
Publikováno v:
Molecular and cellular biology. 26(23)
Signaling by the Ca(2+)/calmodulin kinase (CaMK) cascade has been implicated in neuronal gene transcription, synaptic plasticity, and long-term memory consolidation. The CaM kinase kinase alpha (CaMKKalpha) isoform is an upstream component of the CaM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f06b0086654fe0d7706d78148d89fa
https://pubmed.ncbi.nlm.nih.gov/17015467
https://pubmed.ncbi.nlm.nih.gov/17015467
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 167(11)
The outcome of thymocyte selection is influenced by the nature of Ca2+ signals transduced by the TCR. Robust Ca2+ responses characterize high-affinity, negatively selecting peptide/TCR interactions, while modest responses typify lower-affinity, posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907efeeed11a3f5d9372bbd1f55464ad
https://pubmed.ncbi.nlm.nih.gov/11714790
https://pubmed.ncbi.nlm.nih.gov/11714790
Autor:
Lisa M. Muglia, Jason Liauw, David M. Holtzman, Feng Wei, Frank Blaeser, Silva H. Hanissian, Min Zhuo, A. Nardi, David F. Wozniak, David J. Linden, Nga Ho, Talal A. Chatila, Louis J. Muglia, Kara L. Arvin
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 20(17)
The Ca(2+)/calmodulin-dependent protein kinase type IV/Gr (CaMKIV/Gr) is a key effector of neuronal Ca(2+) signaling; its function was analyzed by targeted gene disruption in mice. CaMKIV/Gr-deficient mice exhibited impaired neuronal cAMP-responsive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957cf08c96dfc3fd8f2c74dda4bf0c75
https://pubmed.ncbi.nlm.nih.gov/10964952
https://pubmed.ncbi.nlm.nih.gov/10964952
Autor:
Michael J. Holtzman, Hani Harb, Holger Garn, Brian O'Connor, Hong S. Kim, Raffi Tachdjian, Shadi Al Khatib, Talal A. Chatila, Clinton B. Mathias, Hans C. Oettgen, Danuta Rzymkiewicz, Harald Renz, Paul J. Bryce, Gurjit K. Khurana Hershey, Frank Blaeser, A. W. Chen
Publikováno v:
BASE-Bielefeld Academic Search Engine
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Polymorphisms in the interleukin-4 receptor alpha chain (IL-4R alpha) have been linked to asthma incidence and severity, but a causal relationship has remained uncertain. In particular, a glutamine to arginine substitution at position 576 (Q576R) of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a348c373627d6d6f5aa4dee75a3a2c
http://nrs.harvard.edu/urn-3:HUL.InstRepos:5350698
http://nrs.harvard.edu/urn-3:HUL.InstRepos:5350698
