Comparative efficacy of low-dose versus standard-dose azithromycin for patients with yaws: a randomised non-inferiority trial in Ghana and Papua New Guinea

Autor: Michael Marks, PhD, Oriol Mitjà, PhD, Christian Bottomley, PhD, Cynthia Kwakye, PhD, Wendy Houinei, DPH, Mathias Bauri, MPH, Paul Adwere, MPH, Abdul A Abdulai, MPH, Fredrick Dua, MD, Laud Boateng, MPH, James Wangi, MD, Sally-Ann Ohene, MPH, Regina Wangnapi, MD, Shirley V Simpson, MPhil, Helen Miag, HEO, Kennedy K Addo, ProfPhD, Laud A Basing, MPhil, Damien Danavall, BSc, Kai H Chi, MSc, Allan Pillay, PhD, Ronald Ballard, ProfPhD, Anthony W Solomon, PhD, Cheng Y Chen, PhD, Sibauk V Bieb, MAHM, Yaw Adu-Sarkodie, ProfPhD, David C W Mabey, ProfFRCP, Kingsley Asiedu, MPH, Michael Marks, Oriol Mitjà, Christian Bottomley, Cynthia Kwakye, Wendy Hounei, Mathias Bauri, Paul Adwere, Abdul A Abdulai, Fredrick Dua, Laud Boateng, James Wangi, Sayy-Ann Ohene, Regina Wangnapi, Shirley V Simpson, Helen Miag, Kennedy K Addo, Laud A Basing, Damien Danavall, Kai H Chi, Allan Pillay, Ronald Ballard, Anthony W Solomon, Cheng Y Chen, Sivuak V Bieb, Yaw Adu-Sarkodie, David CW Mabey, Kingsley Asiedu, Nsire Agana, Edwin Ampadu, Kwame Amponsah-Achiano, Asare Bediako, Michael Biredu, Kyei Faried, Ahmed Iddrisu, Nana K Kotey, George NY Yeboah, Philip El-Duah, Richard Phillips, Fred Binka, Frank Nyonator, Anthony Zunuo, Mercy A Ackumey, Ivy Amanor, Christian Bnosu, Sieghard Frischmann, Patrick Lammie, Diana Martin, Tun Ye, Eva Christophel, Alexandre Tiendrebeogo, Lasse Vestergard, Quique Bassat, Yazid Abdad, Henson Dima, Bethuel Kotty, Kaiok Mamore, Walerius Manup, Benson Olowau, Enoch O Agyei, David Agyemang, Ebenezer P Ako, Prince Antwi, Jane Darko, Ophelia O Darko, Phylis Darko, Bertha Duodu, Daniel Jabasi, Fuseini L Karim, Obed K Koomson, Bernard A Labri, John Nartey, Randsford Tamatey, Benjamin Yirenkyi, Mercy Arhin, Frank Biney, Juliana O Danso, Martin A Dei, Moses Djan, Samuel Sasu, Brefo A Solomon, Victor Torvinya, Hagar Amankwaah, James Baffoe, Lydia Keteku, Kofi Kondobala, Rita D Lomotey, Augustina A Nartey, Paul Oppong, Millicent A Quainoo, Theophilus Abotsi, Dzighordi Agebshie, Amos Ameamu, Paul Angwaawie, Rose Ayibor, Margaret Mwingmendeli, John Nakodia, Amatus Nambagyira, Dominic Nanga, Nichola Tetteh, Augustine Wanaom

Publikováno v: The Lancet Global Health, Vol 6, Iss 4, Pp e401-e410 (2018)

Summary: Background: A dose of 30 mg/kg of azithromycin is recommended for treatment of yaws, a disease targeted for global eradication. Treatment with 20 mg/kg of azithromycin is recommended for the elimination of trachoma as a public health problem

Externí odkaz: https://doaj.org/article/80d8729e29194b8a92aac058ab687ea6

Community-based mass treatment with azithromycin for the elimination of yaws in Ghana-Results of a pilot study

Autor: Damien Danavall, Shirley Victoria Simpson, Yaw Adu-Sarkodie, Oriol Mitjà, Sergi Sanz, Kai-Hua Chi, Abdul Aziz Abdulai, Kingsley Asiedu, Sardick Kyei-Faried, Ronald C. Ballard, George Bonsu, Kwame Amponsa-Achiano, Ye Tun, Patrick Agana-Nsiire, William Ampofo, Frank Biney, Cynthia Kwakye-Maclean, Cheng Y. Chen, Sally-Ann Ohene, Allan Pillay, Kennedy Kwasi Addo

Publikováno v: PLoS Neglected Tropical Diseases, Vol 12, Iss 3, p e0006303 (2018)
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS Neglected Tropical Diseases
Recercat. Dipósit de la Recerca de Catalunya
instname

Introduction The WHO yaws eradication strategy consists of one round of total community treatment (TCT) of single-dose azithromycin with coverage of > 90%.The efficacy of the strategy to reduce the levels on infection has been demonstrated previously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d2471cd4f1d6e5a2911474027fe51b2
http://hdl.handle.net/2445/134611