Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Frank Bicker"'
EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors
Autor:
Nevenka Dudvarski Stanković, Frank Bicker, Stefanie Keller, David TW Jones, Patrick N Harter, Arne Kienzle, Clarissa Gillmann, Philipp Arnold, Anna Golebiewska, Olivier Keunen, Alf Giese, Andreas von Deimling, Tobias Bäuerle, Simone P Niclou, Michel Mittelbronn, Weilan Ye, Stefan M Pfister, Mirko HH Schmidt
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 9, Pp 1-19 (2018)
Abstract Glioblastoma (GBM) is a typically lethal type of brain tumor with a median survival of 15 months postdiagnosis. This negative prognosis prompted the exploration of alternative treatment options. In particular, the reliance of GBM on angiogen
Externí odkaz:
https://doaj.org/article/da5be89c68214918bc8541961d52a2fb
Autor:
Catherine Larochelle, Timo Uphaus, Bieke Broux, Elizabeth Gowing, Magdalena Paterka, Laure Michel, Nevenka Dudvarski Stankovic, Frank Bicker, Florent Lemaître, Alexandre Prat, Mirko H. H. Schmidt, Frauke Zipp
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Endothelial cells release extracellular matrix components that regulate inflammation. Here the authors demonstrate that the extracellular matrix component epidermal growth factor-like protein 7 regulates inflammation in experimental autoimmune enceph
Externí odkaz:
https://doaj.org/article/267ce7d3e5f2468796ef7433fcb27a1c
Autor:
Frank Bicker, Verica Vasic, Guilherme Horta, Felipe Ortega, Hendrik Nolte, Atria Kavyanifar, Stefanie Keller, Nevenka Dudvarski Stankovic, Patrick N. Harter, Rui Benedito, Beat Lutz, Tobias Bäuerle, Jens Hartwig, Jan Baumgart, Marcus Krüger, Konstantin Radyushkin, Lavinia Alberi, Benedikt Berninger, Mirko H. H. Schmidt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
The vascular stem cell niche regulates the proliferation and differentiation of neural stem cells (NSCs) in the adult subventricular zone. Here the authors identify EGFL7 as a neurovascular regulator of NSCsin vivo; EGFL7-knockout mice show reduced n
Externí odkaz:
https://doaj.org/article/893b1f84a39b4db9ad2ea276781e4fdb
Autor:
Kathrin Barth, Verica Vasić, Brennan McDonald, Nora Heinig, Marc-Christoph Wagner, Ulrike Schumann, Cora Röhlecke, Frank Bicker, Lana Schumann, Konstantin Radyushkin, Jan Baumgart, Stefan Tenzer, Frauke Zipp, Matthias Meinhardt, Kari Alitalo, Irmgard Tegeder, Mirko H. H. Schmidt
Neural stem cells reside in the subgranular zone, a specialized neurogenic niche of the hippocampus. Throughout adulthood, these cells give rise to neurons in the dentate gyrus, playing an important role in learning and memory. Given that these core
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047f5a725af1602ed08b3f85f90ec486
http://hdl.handle.net/10138/355996
http://hdl.handle.net/10138/355996
Publikováno v:
Journal of Neurochemistry. 159:452-478
Autism spectrum disorder (ASD) comprises a group of multifactorial neurodevelopmental disorders primarily characterized by deficits in social interaction and repetitive behavior. Although the onset is typically in early childhood, ASD poses a lifelon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02939adfda2b3fd503ae34cb6abf007f
https://doi.org/10.1111/jnc.15501
https://doi.org/10.1111/jnc.15501
Autor:
Verica Vasić, Kathrin Barth, Frank Bicker, Ulrike Schumann, Christine Maurer, Nora Heinig, Cora Röhlecke, Ute Nimtschke, Lana Schumann, Matthias Meinhardt, Thomas Mittmann, Konstantin Radyushkin, Jan Baumgart, Stefan Tenzer, Frauke Zipp, Irmgard Tegeder, Mirko HH Schmidt
Neural stem cells reside in a specialized neurogenic niche of the hippocampus termed the subgranular zone. Throughout life, they give rise to adult-born neurons in the dentate gyrus thereby contributing to learning and memory. Here, we report that ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccde5a485c6b002a7bf134fcbd4dce3f
https://doi.org/10.1101/2022.04.07.487327
https://doi.org/10.1101/2022.04.07.487327
EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors
Autor:
Anna Golebiewska, Weilan Ye, Alf Giese, Nevenka Dudvarski Stankovic, David T.W. Jones, Tobias Bäuerle, Arne Kienzle, Olivier Keunen, Frank Bicker, Philipp Arnold, Clarissa Gillmann, Michel Mittelbronn, Andreas von Deimling, Stefan M. Pfister, Patrick N. Harter, Stefanie Keller, Simone P. Niclou, Mirko H. H. Schmidt
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 10, Iss 9, Pp n/a-n/a (2018)
EMBO Molecular Medicine, Vol 10, Iss 9, Pp n/a-n/a (2018)
Glioblastoma (GBM) is a typically lethal type of brain tumor with a median survival of 15 months postdiagnosis. This negative prognosis prompted the exploration of alternative treatment options. In particular, the reliance of GBM on angiogenesis trig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7f8d604b852e7f91748008d00cd31c
http://europepmc.org/articles/PMC6127886
http://europepmc.org/articles/PMC6127886
Autor:
Timo Uphaus, Florent Lemaître, Laure Michel, Alexandre Prat, Frank Bicker, Bieke Broux, Mirko H. H. Schmidt, Nevenka Dudvarski Stankovic, Catherine Larochelle, Frauke Zipp, Magdalena Paterka, Elizabeth Gowing
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
Extracellular matrix (ECM) proteins secreted by blood-brain barrier (BBB) endothelial cells (ECs) are implicated in cell trafficking. We discovered that the expression of ECM epidermal growth factor-like protein 7 (EGFL7) is increased in the CNS vasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c17f53b0ea36245796545962848a6be
https://doi.org/10.1038/s41467-018-03186-z
https://doi.org/10.1038/s41467-018-03186-z
Autor:
Verena Opitz, Julia Bruttger, Mirko H. H. Schmidt, Stefanie Keller, Betty Jurek, Tobias Bäuerle, Fabien Binamé, René Gollan, Frank Bicker, Michael K. E. Schäfer, Frauke Zipp, Jérôme Birkenstock, Valérie Jolivel, Robert Ploen, Laura Poisa-Beiro, Serge C. Thal, Ari Waisman
Publikováno v:
Acta Neuropathologica. 129:279-295
The contribution of microglia to ischemic cortical stroke is of particular therapeutic interest because of the impact on the survival of brain tissue in the ischemic penumbra, a region that is potentially salvable upon a brain infarct. Whether or not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f81be7e8a5a5117d4538e912063631d
https://doi.org/10.1007/s00401-014-1372-1
https://doi.org/10.1007/s00401-014-1372-1
Autor:
Beat Lutz, Marcus Krüger, Benedikt Berninger, Guilherme Horta, Felipe Ortega, Jan Baumgart, Stefanie Keller, Patrick N. Harter, Tobias Bäuerle, Nevenka Dudvarski Stankovic, Frank Bicker, Konstantin Radyushkin, Mirko H. H. Schmidt, Lavinia Alberi, Rui Benedito, Hendrik Nolte, Atria Kavyanifar, Jens Hartwig, Verica Vasic
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Nature Communications
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications
Repisalud
Instituto de Salud Carlos III (ISCIII)
Adult neural stem cells reside in a specialized niche in the subventricular zone (SVZ). Throughout life they give rise to adult-born neurons in the olfactory bulb (OB), thus contributing to neural plasticity and pattern discrimination. Here, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4553ea59b56aa8bc1be26baaaf791ca0
https://hdl.handle.net/20.500.12105/5110
https://hdl.handle.net/20.500.12105/5110