Zobrazeno 1 - 10
of 410
pro vyhledávání: '"Frank Barry"'
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Background Despite a long history of investigation and sustained efforts in clinical testing, the number of market authorisations for mesenchymal stromal cell (MSC) therapies remains limited, with none approved by the United States Food and
Externí odkaz:
https://doaj.org/article/97f40d04e74f455aa1951fe399de8783
Autor:
Thomas Schwarzl, Andrea Keogh, Georgina Shaw, Aleksandar Krstic, Elizabeth Clayton, Desmond G. Higgins, Walter Kolch, Frank Barry
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-6 (2023)
Abstract Articular cartilage has only very limited regenerative capacities in humans. Tissue engineering techniques for cartilage damage repair are limited in the production of hyaline cartilage. Mesenchymal stem/stromal cells (MSCs) are multipotent
Externí odkaz:
https://doaj.org/article/7c94cce76ce645939115b06e167c47f5
Autor:
Yolande F. M. Ramos, Tobias Tertel, Georgina Shaw, Simon Staubach, Rodrigo Coutinho de Almeida, Eka Suchiman, Thomas B. Kuipers, Hailiang Mei, Frank Barry, Mary Murphy, Bernd Giebel, Ingrid Meulenbelt
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-9 (2022)
Abstract Although mesenchymal stromal cells (MSCs) from primary tissues have been successfully applied in the clinic, their expansion capabilities are limited and results are variable. MSCs derived from human-induced pluripotent stem cells (hiMSCs) a
Externí odkaz:
https://doaj.org/article/f47d5a4719634e208aaaf4cc43ff7a76
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Following a one medicine approach, the development of regenerative therapies for human patients leads to innovative treatments for animals, while pre-clinical studies on animals provide knowledge to advance human medicine. Among many different biolog
Externí odkaz:
https://doaj.org/article/56f26d93b3dd4363acdd96a61ea15858
Autor:
Jelena Ochs, Mariana P. Hanga, Georgina Shaw, Niamh Duffy, Michael Kulik, Nokilaj Tissin, Daniel Reibert, Ferdinand Biermann, Panagiota Moutsatsou, Shibani Ratnayake, Alvin Nienow, Niels Koenig, Robert Schmitt, Qasim Rafiq, Christopher J. Hewitt, Frank Barry, J. Mary Murphy
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 3, Pp n/a-n/a (2022)
Abstract Advanced therapeutic medicinal products (ATMPs) have emerged as novel therapies for untreatable diseases, generating the need for large volumes of high‐quality, clinically‐compliant GMP cells to replace costly, high‐risk and limited sc
Externí odkaz:
https://doaj.org/article/8d664c132f564d2da30264fa84d60be3
Orthobiologics in orthopedic applications: a report from the TMI Havemeyer meeting on orthobiologics
Autor:
Christian Lattermann, Chilan B.G. Leite, David D. Frisbie, Theodore S. Schlegel, Larry R. Bramlage, Thomas Koch, Christopher Centeno, Laurie R. Goodrich, Brian Johnstone, Rocci Trumper, Ashlee Watts, Christopher Little, Frank Barry, Farsh Guilak, C. Wayne McIlwraith
Publikováno v:
Journal of Cartilage & Joint Preservation, Vol 2, Iss 3, Pp 100055- (2022)
Readily available and effective therapeutic approaches are increasingly required to overcome the growing demand for optimized management of musculoskeletal degenerative conditions. The use of biologic therapies has been gaining ground in the orthoped
Externí odkaz:
https://doaj.org/article/a8f85c5b8fcd4d33be0f8938b705ef55
Autor:
Ana Ivanovska, Mengyu Wang, Tarlan Eslami Arshaghi, Georgina Shaw, Joel Alves, Andrew Byrne, Steven Butterworth, Russell Chandler, Laura Cuddy, James Dunne, Shane Guerin, Rob Harry, Aidan McAlindan, Ronan A. Mullins, Frank Barry
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
The recent interest in advanced biologic therapies in veterinary medicine has opened up opportunities for new treatment modalities with considerable clinical potential. Studies with mesenchymal stromal cells (MSCs) from animal species have focused on
Externí odkaz:
https://doaj.org/article/395cd5c9beec4098ab5cd5798dee3429
Autor:
Joan C. Fitzgerald, Niamh Duffy, Giacomo Cattaruzzi, Francesco Vitrani, Alice Paulitti, Flavia Mazzarol, Prisca Mauro, Antonio Sfiligoj, Francesco Curcio, Deirdre M. Jones, Veronica McInerney, Janusz Krawczyk, Jack Kelly, Andrew Finnerty, Katya McDonagh, Una McCabe, Matthew Duggan, Lauren Connolly, Georgina Shaw, Mary Murphy, Frank Barry
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
In recent years mesenchymal stromal cells (MSCs) have received a great deal of interest for the treatment of major diseases, but clinical translation and market authorization have been slow. This has been due in part to a lack of standardization in c
Externí odkaz:
https://doaj.org/article/7945c89fae8f404c8b04f0e9d61db25e
Autor:
Shahd Horie, Claire Masterson, Jack Brady, Paul Loftus, Emma Horan, Lisa O’Flynn, Steve Elliman, Frank Barry, Timothy O’Brien, John G. Laffey, Daniel O’Toole
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2020)
Abstract Background Mesenchymal stromal cells (MSCs) demonstrate considerable promise for acute respiratory distress syndrome (ARDS) and sepsis. However, standard approaches to MSC isolation generate highly heterogeneous cell populations, while bone
Externí odkaz:
https://doaj.org/article/dd72cc88eb7a44899c617e1dd9e90e46
Autor:
Shahd Horie, Sean Gaynard, Mary Murphy, Frank Barry, Michael Scully, Daniel O’Toole, John G. Laffey
Publikováno v:
Intensive Care Medicine Experimental, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Background Human mesenchymal stem/stromal cells (hMSCs) represent a promising therapeutic strategy for ventilator-induced lung injury (VILI) and acute respiratory distress syndrome. Translational challenges include restoring hMSC efficacy fo
Externí odkaz:
https://doaj.org/article/a5f6bda4293f4ae6bc17938581e83a10