Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Frank A.E. Kruyt"'
Autor:
Bianca Dijkstra, Quirine C.F. Cordia, Julie Nonnekens, Gert Jan Meersma, Venkata S. Donthu, Michiel Wagemakers, Rob A. Vergeer, Gijs Rijtema, Wouter Nagengast, Schelto Kruijff, Wilfred F.A. den Dunnen, Frank A.E. Kruyt, Rob J.M. Groen
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 102138- (2023)
Externí odkaz:
https://doaj.org/article/3196548471a546ab8e237a2209b29718
Autor:
Walderik W. Zomerman, Sabine L.A. Plasschaert, Siobhan Conroy, Frank J. Scherpen, Tiny G.J. Meeuwsen-de Boer, Harm J. Lourens, Sergi Guerrero Llobet, Marlinde J. Smit, Lorian Slagter-Menkema, Annika Seitz, Corrie E.M. Gidding, Esther Hulleman, Pieter Wesseling, Lisethe Meijer, Leon C. van Kempen, Anke van den Berg, Daniël O. Warmerdam, Frank A.E. Kruyt, Floris Foijer, Marcel A.T.M. van Vugt, Wilfred F.A. den Dunnen, Eelco W. Hoving, Victor Guryev, Eveline S.J.M. de Bont, Sophia W.M. Bruggeman
Publikováno v:
Cell Reports, Vol 22, Iss 12, Pp 3206-3216 (2018)
Summary: The brain cancer medulloblastoma consists of different transcriptional subgroups. To characterize medulloblastoma at the phosphoprotein-signaling level, we performed high-throughput peptide phosphorylation profiling on a large cohort of SHH
Externí odkaz:
https://doaj.org/article/29d5a08e9ade4e27a193d73891378371
Tumour-necrosis factor related apoptosis-inducing ligand (TRAIL) receptors (TRAIL-R1 and -R2) are appealing therapeutic targets to eradicate tumours specifically via caspase-dependent apoptosis. However, resistance is often observed and TRAIL-R activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d656eb8a441f7abd7443d039c2991e4e
https://doi.org/10.1101/2022.08.10.503463
https://doi.org/10.1101/2022.08.10.503463
Autor:
Marion de Jong, Yann Seimbille, Schelto Kruijff, Rob J. M. Groen, Clemens W G M Löwik, Bianca M. Dijkstra, Wilfred F. A. den Dunnen, Laura Mezzanotte, Frank A.E. Kruyt, Sebastiaan E. Dulfer, Marcus C. M. Stroet, Kranthi M. Panth
Publikováno v:
EJNMMI Research, 11(1):47, 1-8. SpringerOpen
EJNMMI research, vol. 11, no. 1, pp. 47
EJNMMI Research, 11:47. Springer-Verlag
EJNMMI Research, Vol 11, Iss 1, Pp 1-8 (2021)
EJNMMI research, vol. 11, no. 1, pp. 47
EJNMMI Research, 11:47. Springer-Verlag
EJNMMI Research, Vol 11, Iss 1, Pp 1-8 (2021)
Background There is a growing body of nuclear contrast agents that are repurposed for fluorescence-guided surgery. New contrast agents are obtained by substituting the radioactive tag with, or adding a fluorescent cyanine to the molecular structure o
Autor:
Reinoud Gosens, Frank A.E. Kruyt, Coby Meijer, Win Sen Heng, Shiau-Chuen Cheah, Milind Pore, T. Jeroen N. Hiltermann
Publikováno v:
Lung Cancer, 154, 13-22. ELSEVIER IRELAND LTD
OBJECTIVES: Cancer stem cells (CSCs) have been implicated in disease progression of aggressive cancers including small cell lung carcinoma (SCLC). Here, we have examined the possible contribution of CSCs to SCLC progression and aggressiveness.MATERIA
Autor:
Marieke Everts, Wilfred F. A. den Dunnen, Julie Nonnekens, Rob J. M. Groen, Frank A.E. Kruyt, Fritz Andreae, Marcus C. M. Stroet, Bianca M. Dijkstra, Schelto Kruijff, Marion de Jong, Sebastiaan E. Dulfer
Publikováno v:
Journal of Neuro-Oncology, 153(2), 211-222. Kluwer Academic
JOURNAL OF NEURO-ONCOLOGY, 153(2), 211-222. SPRINGER
Journal of Neuro-Oncology
JOURNAL OF NEURO-ONCOLOGY, 153(2), 211-222. SPRINGER
Journal of Neuro-Oncology
Purpose Meningioma recurrence rates can be reduced by optimizing surgical resection with the use of intraoperative molecular fluorescence guided surgery (MFGS). We evaluated the potential of the fluorescent tracer 800CW-TATE for MFGS using in vitro a
Autor:
Tushar Tomar, Barbara Klink, Rolf Bjerkvig, Lars A. Rømo Ystaas, Zhang Di, Frida Haukas, Heiko Wurdak, Justine Rudewicz, Frode S. Berven, Amalie Trones, Lalit Rane, Justin V. Joseph, Even Birkeland, Sylvain Cuvellier, Frank Winkler, Frank A.E. Kruyt, Peter O'Toole, Jubayer A Hossain, Jian Wang, Matteo Gambaretti, Joanne Marrison, Thomas Mathivet, Andreas Bikfalvi, Wenjing Zhou, Hrvoje Miletic, Thomas Daubon, Bronwyn K. Irving, Sandra Ninzima, Simon Storevik, Luiz H. Geraldo, Capucine R. Magaut, Abdul Latif, Joris Guyon
Publikováno v:
Neuro-Oncology
Neuro-Oncology, Oxford University Press (OUP), 2021, ⟨10.1093/neuonc/noab212⟩
Joseph, J V, Magaut, C R, Storevik, S, Geraldo, L H, Mathivet, T, Latif, M A, Rudewicz, J, Guyon, J, Gambaretti, M, Haukas, F, Trones, A, Rømo Ystaas, L A, Hossain, J A, Ninzima, S, Cuvellier, S, Zhou, W, Tomar, T, Klink, B, Rane, L, Irving, B K, Marrison, J, O'Toole, P, Wurdak, H, Wang, J, Di, Z, Birkeland, E, Berven, F S, Winkler, F, Kruyt, F A E, Bikfalvi, A, Bjerkvig, R, Daubon, T & Miletic, H 2022, ' TGF-β promotes microtube formation in glioblastoma through thrombospondin 1 ', Neuro-Oncology, vol. 24, no. 4, pp. 541-553 . https://doi.org/10.1093/neuonc/noab212
Neuro-Oncology, 24(4). Oxford University Press
Neuro-Oncology, Oxford University Press (OUP), 2021, ⟨10.1093/neuonc/noab212⟩
Joseph, J V, Magaut, C R, Storevik, S, Geraldo, L H, Mathivet, T, Latif, M A, Rudewicz, J, Guyon, J, Gambaretti, M, Haukas, F, Trones, A, Rømo Ystaas, L A, Hossain, J A, Ninzima, S, Cuvellier, S, Zhou, W, Tomar, T, Klink, B, Rane, L, Irving, B K, Marrison, J, O'Toole, P, Wurdak, H, Wang, J, Di, Z, Birkeland, E, Berven, F S, Winkler, F, Kruyt, F A E, Bikfalvi, A, Bjerkvig, R, Daubon, T & Miletic, H 2022, ' TGF-β promotes microtube formation in glioblastoma through thrombospondin 1 ', Neuro-Oncology, vol. 24, no. 4, pp. 541-553 . https://doi.org/10.1093/neuonc/noab212
Neuro-Oncology, 24(4). Oxford University Press
Background Microtubes (MTs), cytoplasmic extensions of glioma cells, are important cell communication structures promoting invasion and treatment resistance through network formation. MTs are abundant in chemoresistant gliomas, in particular, gliobla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4668e5475d8914bb38b01f4e352afc0e
https://hal.archives-ouvertes.fr/hal-03442147
https://hal.archives-ouvertes.fr/hal-03442147
Publikováno v:
Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 2021, 192, pp.114737. ⟨10.1016/j.bcp.2021.114737⟩
Biochemical Pharmacology, 2021, 192, pp.114737. ⟨10.1016/j.bcp.2021.114737⟩
Biochemical Pharmacology, Elsevier, 2021, 192, pp.114737. ⟨10.1016/j.bcp.2021.114737⟩
Biochemical Pharmacology, 2021, 192, pp.114737. ⟨10.1016/j.bcp.2021.114737⟩
International audience; The unfolded protein response (UPR) is an adaptive mechanism that regulates protein and cellular homeostasis. Three endoplasmic reticulum (ER) membrane localized stress sensors, IRE1, PERK and ATF6, coordinate the UPR in order
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5a338143af981480beeebe73580705
https://hal.archives-ouvertes.fr/hal-03334034/document
https://hal.archives-ouvertes.fr/hal-03334034/document
Publikováno v:
Current Opinion in Pharmacology, 61, 91-97. ELSEVIER SCI LTD
Current Opinion in Pharmacology
Current Opinion in Pharmacology, Elsevier, 2021, 61, pp.91-97. ⟨10.1016/j.coph.2021.08.019⟩
Vareecal Joseph, J, Blaavand, M S, Daubon, T, Kruyt, F AE & Thomsen, M K 2021, ' Three-dimensional culture models to study glioblastoma — current trends and future perspectives ', Current Opinion in Pharmacology, vol. 61, pp. 91-97 . https://doi.org/10.1016/j.coph.2021.08.019
Joseph, J V, Blaavand, M S, Daubon, T, Kruyt, F AE & Thomsen, M K 2021, ' Three-dimensional culture models to study glioblastoma — current trends and future perspectives ', Current Opinion in Pharmacology, vol. 61, pp. 91-97 . https://doi.org/10.1016/j.coph.2021.08.019
Current Opinion in Pharmacology
Current Opinion in Pharmacology, Elsevier, 2021, 61, pp.91-97. ⟨10.1016/j.coph.2021.08.019⟩
Vareecal Joseph, J, Blaavand, M S, Daubon, T, Kruyt, F AE & Thomsen, M K 2021, ' Three-dimensional culture models to study glioblastoma — current trends and future perspectives ', Current Opinion in Pharmacology, vol. 61, pp. 91-97 . https://doi.org/10.1016/j.coph.2021.08.019
Joseph, J V, Blaavand, M S, Daubon, T, Kruyt, F AE & Thomsen, M K 2021, ' Three-dimensional culture models to study glioblastoma — current trends and future perspectives ', Current Opinion in Pharmacology, vol. 61, pp. 91-97 . https://doi.org/10.1016/j.coph.2021.08.019
Glioblastoma (GBM) is the most prevalent form of primary malignant brain tumor in adults and remains almost invariably lethal owing to its aggressive and invasive nature. There have only been marginal improvements in its bleak survival rate of 12-15
Publikováno v:
Biochemical Pharmacology. 160:121-133
Lung cancer remains the leading cause of cancer-related deaths despite recent breakthroughs in immunotherapy. The widely embraced cancer stem cell (CSC) theory has also been applied for lung cancer, postulating that an often small proportion of tumor