Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Frank A W Coumans"'
Autor:
Linda G Rikkert, Leonie de Rond, Annemieke van Dam, Ton G van Leeuwen, Frank A W Coumans, Theo M de Reijke, Leon W M M Terstappen, Rienk Nieuwland
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233443 (2020)
Large (> 1 μm) tumor-derived extracellular vesicles (tdEVs) enriched from the cell fraction of centrifuged whole blood are prognostic in metastatic castration-resistant prostate cancer (mCRPC) patients. However, the highest concentration of tdEVs is
Externí odkaz:
https://doaj.org/article/0e62668cfaef4da3aacd2e07deabb1d9
Autor:
Sjoerd T Ligthart, Frank A W Coumans, Francois-Clement Bidard, Lieke H J Simkens, Cornelis J A Punt, Marco R de Groot, Gerhardt Attard, Johann S de Bono, Jean-Yves Pierga, Leon W M M Terstappen
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67148 (2013)
BackgroundPresence of circulating tumor cells (CTC) in patients with metastatic breast, colorectal and prostate cancer is indicative for poor prognosis. An automated CTC (aCTC) algorithm developed previously to eliminate the variability in manual cou
Externí odkaz:
https://doaj.org/article/b320d45a94964a0986779d1c7671c4e5
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61770 (2013)
A variety of filters assays have been described to enrich circulating tumor cells (CTC) based on differences in physical characteristics of blood cells and CTC. In this study we evaluate different filter types to derive the properties of the ideal fi
Externí odkaz:
https://doaj.org/article/50432fbd394848a0911dc4a7906f2912
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61774 (2013)
Filtration can achieve circulating tumor cell (CTC) enrichment from blood. Key parameters such as flow-rate, applied pressure, and fixation, vary largely between assays and their influence is not well understood. Here, we used a filtration system, to
Externí odkaz:
https://doaj.org/article/48bddcb7c7614eaeb8860819f1a4755b
Autor:
Sjoerd T Ligthart, Frank A W Coumans, Gerhardt Attard, Amy Mulick Cassidy, Johann S de Bono, Leon W M M Terstappen
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27419 (2011)
Circulating tumour cells (CTC) in patients with metastatic carcinomas are associated with poor survival and can be used to guide therapy. Classification of CTC however remains subjective, as they are morphologically heterogeneous. We acquired digital
Externí odkaz:
https://doaj.org/article/93c1cee4a8f944dbb7599d912fce7739
Publikováno v:
Platelets, Vol 32, Iss 4, Pp 440-443 (2021)
The study of extracellular vesicles (EVs) in plasma requires removal of cells including platelets. At present, a two-step centrifugation protocol is recommended and commonly used. A simpler protocol that is less operator dependent is likely to improv
Externí odkaz:
https://doaj.org/article/08426754a51041b89e49c4def85d0443
Publikováno v:
Platelets, Vol 28, Iss 3, Pp 242-248 (2017)
There is increasing clinical interest in extracellular vesicles (EV) for diagnostic and treatment purposes. This review provides an overview of bulk immunoassays to analyse EV. Western blot and enzyme-linked immunosorbent assay are still the two pred
Externí odkaz:
https://doaj.org/article/f0f3043a064e4e819b53e3eeeba73688
Autor:
Khrystany T. Isebia, Eshwari Dathathri, Noortje Verschoor, Afroditi Nanou, Anouk C. De Jong, Frank A. W. Coumans, Leon W. M. M. Terstappen, Jaco Kraan, John W. M. Martens, Ruchi Bansal, Martijn P. Lolkema
Publikováno v:
Cancers; Volume 14; Issue 18; Pages: 4404
Cancers, 14(18):4404. MDPI
Cancers, 14(18):4404. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, 14(18):4404. MDPI
Cancers, 14(18):4404. Multidisciplinary Digital Publishing Institute (MDPI)
Circulating tumor cell (CTC)- and/or tumor-derived extracellular vesicle (tdEV) loads in the blood of metastatic castration-resistant prostate cancer (CRPC) patients are associated with worse overall survival and can be used as predictive markers of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8e752b281bfe4968b84b5f15b4ca95
https://doi.org/10.3390/cancers14184404
https://doi.org/10.3390/cancers14184404
Autor:
Rienk Nieuwland, Edwin van der Pol, Ton G. van Leeuwen, Leonie de Rond, Frank A. W. Coumans, Joshua A. Welsh
Publikováno v:
Cytometry. Part A, 99(7), 671-679. Wiley-Liss Inc.
Knowledge of the sensitivity of a flow cytometer is essential for data interpretation and comparison. However, light scatter sensitivity currently cannot be quantified due to a lack of a standardized unit. Analogous to the QB approach for fluorescenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc1c2ce33391ddb4fd412f5cb345f3b
https://doi.org/10.1002/cyto.a.24243
https://doi.org/10.1002/cyto.a.24243
Autor:
Chi M. Hau, Rienk Nieuwland, Leon W.M.M. Terstappen, Linda Gerritdina Rikkert, Frank A. W. Coumans
Publikováno v:
Platelets, 32(4), 440-443. Informa Healthcare
The study of extracellular vesicles (EVs) in plasma requires removal of cells including platelets. At present, a two-step centrifugation protocol is recommended and commonly used. A simpler protocol that is less operator dependent is likely to improv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820eec78ab12c6c68bfbf04f3b88aec1
http://www.scopus.com/inward/record.url?scp=85087066393&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85087066393&partnerID=8YFLogxK