Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Frank A, Schildberg"'
Autofluorescence-based tissue characterization enhances clinical prospects of light-sheet-microscopy
Autor:
Alice M. Jacob, Anna F. Lindemann, Julia Wagenpfeil, Sergej Geiger, Yannik C. Layer, Babak Salam, Sarah Panahabadi, Darius Kurt, Maximilian W. M. Wintergerst, Frank A. Schildberg, Daniel Kuetting, Ulrike I. Attenberger, Zeinab Abdullah, Alexander M. C. Böhner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Light sheet fluorescence microscopy (LSFM) is a transformative imaging method that enables the visualization of non-dissected specimen in real-time 3D. Optical clearing of tissues is essential for LSFM, typically employing toxic solvents. He
Externí odkaz:
https://doaj.org/article/9f4f3ba2b17c45cfa0544fa6cff24bbc
Autor:
Su Wang, Sarah Kurth, Christof Burger, Dieter C. Wirtz, Frank A. Schildberg, Robert Ossendorff
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10805 (2024)
Tumor necrosis factor alpha (TNFα), as a key pro-inflammatory cytokine, plays a central role in joint diseases. In recent years, numerous models of TNFα-induced cartilage inflammation have been developed. However, due to the significant differences
Externí odkaz:
https://doaj.org/article/63e1a01a4f97459eabc4e50a0efebfa1
Autor:
Jayagopi Surendar, Roslind K. Hackenberg, Fabio Schmitt-Sánchez, Robert Ossendorff, Kristian Welle, Birgit Stoffel-Wagner, Peter T. Sage, Christof Burger, Dieter C. Wirtz, Andreas C. Strauss, Frank A. Schildberg
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionOsteomyelitis (OMS) is a bone infection causing bone pain and severe complications. A balanced immune response is critical to eradicate infection without harming the host, yet pathogens manipulate immunity to establish a chronic infection
Externí odkaz:
https://doaj.org/article/922235c1563e46b8a14d7d4d6a58e417
Autor:
Robert Ossendorff, Su Wang, Sarah Kurth, Max Jaenisch, Elio Assaf, Andreas C. Strauss, Damien Bertheloot, Kristian Welle, Christof Burger, Dieter C. Wirtz, Frank A. Schildberg
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9136 (2024)
Inflammation models are widely used in the in vitro investigation of new therapeutic approaches for osteoarthritis. TNFα (tumor necrosis factor alpha) plays an important role in the inflammatory process. Current inflammation models lack uniformity a
Externí odkaz:
https://doaj.org/article/79e4ac88a8f54523b88acc81468521d6
Autor:
Indulekha Karunakaran, Jayagopi Surendar, Pia Ransmann, Marius Brühl, Silvia Kowalski, Victoria Frische, Jamil Hmida, Sabine Nachtsheim, Achim Hoerauf, Dieter C. Wirtz, Marc P. Hübner, Andreas C. Strauss, Frank A. Schildberg
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1400 (2024)
Considering the fact that Toxoplasma is a common parasite of humans and Toxoplasma bradyzoites can reside in skeletal muscle, T. gondii-mediated immune responses may modulate the progression and pathophysiology of another musculoskeletal disorder, os
Externí odkaz:
https://doaj.org/article/0cd3972d25754c9d8932f56fe8e19bdd
Autor:
Frank Sebastian Fröschen, Thomas Martin Randau, El-Mustapha Haddouti, Frank Alexander Schildberg, Jacques Dominik Müller-Broich, Werner Götz, Susanne Reimann, Dieter Christian Wirtz, Sascha Gravius
Publikováno v:
Applied Sciences, Vol 14, Iss 8, p 3375 (2024)
The biological reconstruction of periprosthetic acetabular defects is essential for the success of revision total hip arthroplasty. However, a standardized in vivo defect model with good analogy to the human situation is still lacking, which has sign
Externí odkaz:
https://doaj.org/article/b764c692757940448c08de4c9abe7cdf
Autor:
Robert Ossendorff, Lisa Grede, Sebastian Scheidt, Andreas C. Strauss, Christof Burger, Dieter C. Wirtz, Gian M. Salzmann, Frank A. Schildberg
Publikováno v:
Cells, Vol 13, Iss 6, p 546 (2024)
The current gold standard to treat large cartilage defects is autologous chondrocyte transplantation (ACT). As a new surgical method of cartilage regeneration, minced cartilage implantation (MCI) is increasingly coming into focus. The aim of this stu
Externí odkaz:
https://doaj.org/article/51b9c90291f14584bcaa439e9cc759b4
Autor:
El-Mustapha Haddouti, Nina Reinhardt, Robert Ossendorff, Christof Burger, Dieter C. Wirtz, Matias de la Fuente, Frank A. Schildberg
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: Extracorporeal shock wave therapy is a non-invasive and effective option for treating various musculoskeletal disorders. Recent literature indicates that the parameters for extracorporeal shock wave therapy, such as the optimal intensit
Externí odkaz:
https://doaj.org/article/bb6a16c15997482bad6df8f3edac0eff
Autor:
Robert Ossendorff, Sibylle Grad, Tobias Tertel, Dieter C. Wirtz, Bernd Giebel, Verena Börger, Frank A. Schildberg
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionOsteoarthritis (OA) affects a large percentage of the population worldwide. Current surgical and nonsurgical concepts for treating OA only result in symptom-modifying effects. However, there is no disease-modifying therapy available. Extr
Externí odkaz:
https://doaj.org/article/04a77ddf37c745d4acfb2e34949161ea
Autor:
Max Jaenisch, Christian Guder, Robert Ossendorff, Thomas M. Randau, Sascha Gravius, Dieter C. Wirtz, Andreas C. Strauss, Frank A. Schildberg
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 10, p 517 (2023)
Biological augmentation of bony defects in weight-bearing areas of both the acetabulum and the femur remains challenging. The calcium-silicate-based ceramic Baghdadite is a very interesting material to be used in the field of revision total hip arthr
Externí odkaz:
https://doaj.org/article/ddb6ecf0c83f48408b08d19d9f89dce8