Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Frank Lezoualc'h"'
Autor:
Arthur Boileve, Margaux Aize, Maximin Detrait, Laura Brard, Alexandre Lebrun, Vladimir Saplacan, Fabien Brette, Frank Lezoualc’h, Laurent Salle
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 10, Iss , Pp 100102- (2024)
Externí odkaz:
https://doaj.org/article/fa5f0827dd244a6491db588c76d64619
Autor:
Monia Souidi, Jessica Resta, Haikel Dridi, Yvonne Sleiman, Steve Reiken, Karina Formoso, Sarah Colombani, Pascal Amédro, Pierre Meyer, Azzouz Charrabi, Marie Vincenti, Yang Liu, Rajesh Kumar Soni, Frank Lezoualc'h, D.V.M. Stéphane Blot, François Rivier, Olivier Cazorla, Angelo Parini, Andrew R. Marks, Jeanne Mialet‐Perez, Alain Lacampagne, Albano C. Meli
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 2, Pp 536-551 (2024)
Abstract Background Duchenne muscular dystrophy (DMD) is an X‐linked disorder characterized by progressive muscle weakness due to the absence of functional dystrophin. DMD patients also develop dilated cardiomyopathy (DCM). We have previously shown
Externí odkaz:
https://doaj.org/article/86cf946208c7405482fdfb4f8454571b
Autor:
Bastien Guillot, Arthur Boileve, Richard Walton, Alexandre Harfoush, Caroline Conte, Yannis Sainte-Marie, Sabine Charron, Olivier Bernus, Alice Recalde, Laurent Sallé, Fabien Brette, Frank Lezoualc’h
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with increased mortality and morbidity. The Exchange Protein directly Activated by cAMP (EPAC), has been implicated in pro-arrhythmic signaling p
Externí odkaz:
https://doaj.org/article/35329e6958d04057bee15723d33b5d65
Autor:
Marion Laudette, Yannis Sainte-Marie, Grégoire Cousin, Dorian Bergonnier, Ismahane Belhabib, Stéphanie Brun, Karina Formoso, Loubna Laib, Florence Tortosa, Camille Bergoglio, Bertrand Marcheix, Jan Borén, Olivier Lairez, Jérémy Fauconnier, Alexandre Lucas, Jeanne Mialet-Perez, Cédric Moro, Frank Lezoualc’h
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-14 (2021)
Abstract Cyclic adenosine monophosphate (cAMP) is a master regulator of mitochondrial metabolism but its precise mechanism of action yet remains unclear. Here, we found that a dietary saturated fatty acid (FA), palmitate increased intracellular cAMP
Externí odkaz:
https://doaj.org/article/097d49210f5941459368a2114f15c98f
Autor:
Clément Delmas, Jean Porterie, Géraldine Jourdan, Frank Lezoualc'h, Romain Arnaud, Stéphanie Brun, Hugo Cavalerie, Grégoire Blanc, Bertrand Marcheix, Olivier Lairez, Patrick Verwaerde, Jeanne Mialet-Perez
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundMechanical circulatory supports are used in case of cardiogenic shock (CS) refractory to conventional therapy. Several devices can be employed, but are limited by their availability, benefit risk-ratio, and/or cost.AimsTo investigate the fe
Externí odkaz:
https://doaj.org/article/2eef7682fcd54727866b4bf21378aaeb
Autor:
Charlotte Foret-Lucas, Thomas Figueroa, Alexandre Bertin, Pierre Bessière, Alexandre Lucas, Dorian Bergonnier, Marine Wasniewski, Alexandre Servat, Arnaud Tessier, Frank Lezoualc’h, Romain Volmer
Publikováno v:
Viruses, Vol 15, Iss 2, p 319 (2023)
The exceptional impact of the COVID-19 pandemic has stimulated an intense search for antiviral molecules. Host-targeted antiviral molecules have the potential of presenting broad-spectrum antiviral activity and are also considered as less likely to s
Externí odkaz:
https://doaj.org/article/b119f7750e944008af44c6af1bf80396
Autor:
Deborah Carper, Marine Coué, Emmani B.M. Nascimento, Valentin Barquissau, Damien Lagarde, Carine Pestourie, Claire Laurens, Justine Vily Petit, Maud Soty, Laurent Monbrun, Marie-Adeline Marques, Yannick Jeanson, Yannis Sainte-Marie, Aline Mairal, Sébastien Déjean, Geneviève Tavernier, Nathalie Viguerie, Virginie Bourlier, Frank Lezoualc’h, Audrey Carrière, Wim H.M. Saris, Arne Astrup, Louis Casteilla, Gilles Mithieux, Wouter van Marken Lichtenbelt, Dominique Langin, Patrick Schrauwen, Cedric Moro
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108075- (2020)
Summary: Atrial natriuretic peptide (ANP) is a cardiac hormone controlling blood volume and pressure in mammals. It is still unclear whether ANP controls cold-induced thermogenesis in vivo. Here, we show that acute cold exposure induces cardiac ANP s
Externí odkaz:
https://doaj.org/article/c9d2ea13dbdc43ab985db4bbda177cc5
Autor:
Nshunge Musheshe, Asmaa Oun, Angélica María Sabogal-Guáqueta, Marina Trombetta-Lima, Sarah C. Mitchel, Ahmed Adzemovic, Oliver Speek, Francesca Morra, Christina H. J. T. van der Veen, Frank Lezoualc’h, Xiaodong Cheng, Martina Schmidt, Amalia M. Dolga
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 314 (2022)
Exchange proteins directly activated by cAMP (Epac) proteins are implicated in a wide range of cellular functions including oxidative stress and cell survival. Mitochondrial-dependent oxidative stress has been associated with progressive neuronal dea
Externí odkaz:
https://doaj.org/article/009fc53d16c244329256a53ee1ef32d8
Publikováno v:
Vascular Biology, Vol 2, Iss 1, Pp R17-R34 (2020)
Pulmonary arterial hypertension (PAH) is a multifactorial cardiopulmonary disease characterized by an elevation of pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR), which can lead to right ventricular (RV) failure, multi-organ
Externí odkaz:
https://doaj.org/article/9bdbfc70af124c64b11efde2ea9dbfa2
Publikováno v:
Cells, Vol 10, Iss 1, p 154 (2021)
β-adrenergic receptors (β-ARs) play a major role in the physiological regulation of cardiac function through signaling routes tightly controlled by G protein-coupled receptor kinases (GRKs). Although the acute stimulation of β-ARs and the subseque
Externí odkaz:
https://doaj.org/article/80e03ad485b2417da5cde443c791e518