Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Frank, de Wolf"'
Autor:
Christoforos Hadjichrysanthou, Stephanie Evans, Sumali Bajaj, Loizos C. Siakallis, Kevin McRae-McKee, Frank de Wolf, Roy M. Anderson, the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2020)
Abstract Background Quantifying changes in the levels of biological and cognitive markers prior to the clinical presentation of Alzheimer’s disease (AD) will provide a template for understanding the underlying aetiology of the clinical syndrome and
Externí odkaz:
https://doaj.org/article/05967c91f4954f1e900612c05b93b109
Autor:
Anna L. Beukenhorst, Clarissa M. Koch, Christoforos Hadjichrysanthou, Galit Alter, Frank de Wolf, Roy M. Anderson, Jaap Goudsmit
Publikováno v:
European Journal of Epidemiology. 38:237-242
Neither vaccination nor natural infection result in long-lasting protection against SARS-COV-2 infection and transmission, but both reduce the risk of severe COVID-19. To generate insights into optimal vaccination strategies for prevention of severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b7eaef43a57357ae60ec45ad239171f
https://doi.org/10.1007/s10654-023-00965-x
https://doi.org/10.1007/s10654-023-00965-x
Autor:
Christoforos Hadjichrysanthou, Anna L. Beukenhorst, Clarissa M. Koch, Galit Alter, Jaap Goudsmit, Roy M. Anderson, Frank de Wolf
Publikováno v:
Infectious Diseases and Therapy. 11:2287-2296
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::074f700681306bb7d54ee7a43fbbee69
https://doi.org/10.1007/s40121-022-00710-z
https://doi.org/10.1007/s40121-022-00710-z
Autor:
Christoforos Hadjichrysanthou, Alison K Ower, Frank de Wolf, Roy M Anderson, Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190615 (2018)
Alzheimer's disease (AD) is a neurodegenerative disorder characterised by a slow progressive deterioration of cognitive capacity. Drugs are urgently needed for the treatment of AD and unfortunately almost all clinical trials of AD drug candidates hav
Externí odkaz:
https://doaj.org/article/7a8c7d965da34f7ca1c6bdface9ffae4
Autor:
Carolin Vegvari, Christoforos Hadjichrysanthou, Emilie Cauët, Emma Lawrence, Anne Cori, Frank de Wolf, Roy M Anderson
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158237 (2016)
Acute viral infections pose many practical challenges for the accurate assessment of the impact of novel therapies on viral growth and decay. Using the example of influenza A, we illustrate how the measurement of infection-related quantities that det
Externí odkaz:
https://doaj.org/article/835179ede52b430eaf27b6de33254814
Autor:
Carolin Vegvari, Emilie Cauët, Christoforos Hadjichrysanthou, Emma Lawrence, Gerrit-Jan Weverling, Frank de Wolf, Roy M Anderson
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156622 (2016)
BACKGROUND:About 90% of drugs fail in clinical development. The question is whether trials fail because of insufficient efficacy of the new treatment, or rather because of poor trial design that is unable to detect the true efficacy. The variance of
Externí odkaz:
https://doaj.org/article/99964cede7554f8c8c3f28b93082593a
Autor:
Kevin McRae-McKee, Stephanie Evans, Christoforos Hadjichrysanthou, Loizos Siakallis, Frank de Wolf, Roy M. Anderson, Sumali Bajaj
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2020)
Alzheimer's Research & Therapy
Alzheimer's Research & Therapy
Background Quantifying changes in the levels of biological and cognitive markers prior to the clinical presentation of Alzheimer’s disease (AD) will provide a template for understanding the underlying aetiology of the clinical syndrome and, concomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4688e54937ff3cff01ebce3cd63f47
http://link.springer.com/article/10.1186/s13195-020-00636-z
http://link.springer.com/article/10.1186/s13195-020-00636-z
Autor:
Alexa S. Beiser, Stéphanie Debette, Daniel Bos, Carol Brayne, Osorio Meirelles, Fiona E. Matthews, Hanna Wetterberg, Sirwan K.L. Darweesh, Claudia L. Satizabal, Kendra Davis-Plourde, Albert Hofman, Erik Joas, Kevin McRae-McKee, Vilmundur Gudnason, Lori B. Chibnik, Bruce M. Psaty, Lewis H. Kuller, Sudha Seshadri, Matthew P. Pase, Blossom C. M. Stephan, Frank J. Wolters, Catherine Helmer, Jean-François Dartigues, Oscar L. Lopez, Leslie Grasset, Silke Kern, Myriam Fornage, Ingmar Skoog, M. Kamran Ikram, Joshua C. Bis, Reem Waziry, Claudine Berr, Anna Zettergren, Roy M. Anderson, Frank de Wolf, Jaap Goudsmit, Thomas H. Mosley, Lenore J. Launer, M. Arfan Ikram, Deborah Blacker, Carole Dufouil, Christoforos Hadjichrysanthou, Mei Mei Wong
Publikováno v:
Neurology, 95(5), e519-e531. Lippincott Williams & Wilkins
e531
e519
e531
e519
ObjectiveTo determine changes in the incidence of dementia between 1988 and 2015.MethodsThis analysis was performed in aggregated data from individuals >65 years of age in 7 population-based cohort studies in the United States and Europe from the Alz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7619b5a582818cc6e084ff06b636458a
https://hdl.handle.net/1765/129458
https://hdl.handle.net/1765/129458
Autor:
Daniela Bezemer, Anne Cori, Oliver Ratmann, Ard van Sighem, Hillegonda S Hermanides, Bas E Dutilh, Luuk Gras, Nuno Rodrigues Faria, Rob van den Hengel, Ashley J Duits, Peter Reiss, Frank de Wolf, Christophe Fraser, ATHENA observational cohort
Publikováno v:
PLoS Medicine, Vol 12, Iss 11, p e1001898; discussion e1001898 (2015)
BackgroundThe HIV-1 subtype B epidemic amongst men who have sex with men (MSM) is resurgent in many countries despite the widespread use of effective combination antiretroviral therapy (cART). In this combined mathematical and phylogenetic study of o
Externí odkaz:
https://doaj.org/article/25f367fdc4be49b7b329f9acbad8c9a3
Autor:
Sumali Bajaj, Roy M. Anderson, Kevin McRae-McKee, Christoforos Hadjichrysanthou, Frank de Wolf
INTRODUCTION: We assessed the association of plasma neurofilament light chain (pNfL) with cognitive decline and neuroimaging markers, and investigated its potential relationship with the clinical progression to dementia due to Alzheimer’s disease (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27af97acde0b3e83d0cb82e96234a95d
https://doi.org/10.21203/rs.3.rs-658952/v1
https://doi.org/10.21203/rs.3.rs-658952/v1
