Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Frank, Stubenrauch"'
Autor:
Franziska Kuehner, Margaret Wong, Elke Straub, John Doorbar, Thomas Iftner, Richard B. S. Roden, Frank Stubenrauch
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT High-risk human papillomaviruses (PV) account for approximately 600,000 new cancers per year. The early protein E8^E2 is a conserved repressor of PV replication, whereas E4 is a late protein that arrests cells in G2 and collapses keratin fil
Externí odkaz:
https://doaj.org/article/83cafb49b78c44eea0451914b3ed452e
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Human papillomaviruses are DNA tumor viruses. A persistent infection with high-risk HPV types is the necessary risk factor for the development of anogenital carcinoma. The E6 protein is a viral oncoprotein that directly interacts with differ
Externí odkaz:
https://doaj.org/article/8a347773f8a54ac0913c28f6f012db3b
Autor:
Jasmin Fertey, Jörg Hagmann, Hans‐Joachim Ruscheweyh, Christian Munk, Susanne Kjaer, Daniel Huson, Juliane Haedicke‐Jarboui, Frank Stubenrauch, Thomas Iftner
Publikováno v:
Cancer Medicine, Vol 9, Iss 3, Pp 1058-1068 (2020)
Abstract Several studies have demonstrated that the viral genome can be methylated by the host cell during progression from persistent infection to cervical cancer. The aim of this study was to investigate whether methylation at a specific site could
Externí odkaz:
https://doaj.org/article/6f62c698defa435bb9517ce21dbf8b2f
Publikováno v:
Virology. 581:39-47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e99b4f2260ff95168cbae1e0e399cfb
https://doi.org/10.1016/j.virol.2023.02.007
https://doi.org/10.1016/j.virol.2023.02.007
Autor:
Franziska Kuehner, Frank Stubenrauch
Publikováno v:
Viruses, Vol 14, Iss 5, p 953 (2022)
Papillomaviruses (PV) replicate in undifferentiated keratinocytes at low levels and to high levels in differentiated cells. The restricted replication in undifferentiated cells is mainly due to the expression of the conserved viral E8^E2 repressor pr
Externí odkaz:
https://doaj.org/article/9b350ff87ced4d58a9c68f1bc8c5430b
Autor:
Suzana Mittelstadt, Olga Kelemen, Jakob Admard, Axel Gschwind, André Koch, Sarah Wörz, Ernst Oberlechner, Tobias Engler, Irina Bonzheim, Annette Staebler, Nicola Weidner, Frank Stubenrauch, Thomas Iftner, Olaf Riess, Christopher Schroeder, Stefan Kommoss, Stephan Ossowski
Publikováno v:
British Journal of Cancer. 128:2097-2103
Background HPV-related cervical cancer (CC) is the fourth most frequent cancer in women worldwide. Cell-free tumour DNA is a potent biomarker to detect treatment response, residual disease, and relapse. We investigated the potential use of cell-free
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e6b64c6390f257ad3c060765d7d3f84
https://doi.org/10.1038/s41416-023-02233-x
https://doi.org/10.1038/s41416-023-02233-x
Autor:
Anna C. Obenauf, Thomas Wiesner, Klaus G. Griewank, Frank Stubenrauch, Arno Rütten, Eduardo Calonje, Lorenzo Cerroni, Reinhard Kirnbauer, Babak Itzinger-Monshi, Klaus J. Busam, Rajmohan Murali, Etienne Coyaud, Kamel Bachiri, Estelle Laurent, Thibault Kervarrec, Karl Mechtler, Michael Schutzbier, Alexander Schleiffer, Thomas L. Steinacker, Shona M. Cronin, Pauline S. Jung, Tobias Neumann, Lukas Leiendecker
HPV42 variant allele frequencies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8142bf251ddf9f1af54e0d32cf2a10a1
https://doi.org/10.1158/2159-8290.22541905
https://doi.org/10.1158/2159-8290.22541905
Autor:
Anna C. Obenauf, Thomas Wiesner, Klaus G. Griewank, Frank Stubenrauch, Arno Rütten, Eduardo Calonje, Lorenzo Cerroni, Reinhard Kirnbauer, Babak Itzinger-Monshi, Klaus J. Busam, Rajmohan Murali, Etienne Coyaud, Kamel Bachiri, Estelle Laurent, Thibault Kervarrec, Karl Mechtler, Michael Schutzbier, Alexander Schleiffer, Thomas L. Steinacker, Shona M. Cronin, Pauline S. Jung, Tobias Neumann, Lukas Leiendecker
The skin is exposed to viral pathogens, but whether they contribute to the oncogenesis of skin cancers has not been systematically explored. Here we investigated 19 skin tumor types by analyzing off-target reads from commonly available next-generatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abd88071e534661631075b72f22a14d
https://doi.org/10.1158/2159-8290.c.6549766.v1
https://doi.org/10.1158/2159-8290.c.6549766.v1
Autor:
Thomas Iftner, Frank Stubenrauch, Sebastian Wesselborg, Martin Busch, Natalie Leiprecht, Johanna Schuetz, Sonja Probst, Peter Muench
Supplementary Data from Cutaneous Papillomavirus E6 Proteins Must Interact with p300 and Block p53-Mediated Apoptosis for Cellular Immortalization and Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c5ec39bb5eedd75026c3631c11b235c
https://doi.org/10.1158/0008-5472.22384943.v1
https://doi.org/10.1158/0008-5472.22384943.v1
Autor:
Suzana Mittelstadt, Christopher Schroeder, Olga Kelemen, Admard Jakob, Axel Gschwind, André Koch, Sarah Wörz, Ernst Oberlechner, Sascha Hoffmann, Tobias Engler, Jürgen Andress, Felix Neis, Bernhard Krämer, Irina Bonzheim, Annette Staebler, Frank Stubenrauch, Stephan Ossowski, Stefan Kommoss
Publikováno v:
Focused Plenary Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a395553fa39ba5248c1a673b067322b
https://doi.org/10.1136/ijgc-2022-igcs.34
https://doi.org/10.1136/ijgc-2022-igcs.34