Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Frank, St Michael"'
Autor:
Janelle Sauvageau, Izel Koyuturk, Frank St. Michael, Denis Brochu, Marie-France Goneau, Ian Schoenhofen, Sylvie Perret, Alexandra Star, Anna Robotham, Arsalan Haqqani, John Kelly, Michel Gilbert, Yves Durocher
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Glycosylation is a key quality attribute that must be closely monitored for protein therapeutics. Established assays such as HILIC-Fld of released glycans and LC-MS of glycopeptides work well for glycoproteins with a few glycosylation sites
Externí odkaz:
https://doaj.org/article/b6b1904909a242f99f4b91f266f9ce1c
Autor:
Simon Joubert, Matthew Stuible, Simon Lord‐Dufour, Linda Lamoureux, François Vaillancourt, Sylvie Perret, Manon Ouimet, Alex Pelletier, Louis Bisson, Rohan Mahimkar, Phuong Lan Pham, Helene L′Ecuyer‐Coelho, Marjolaine Roy, Robert Voyer, Jason Baardsnes, Janelle Sauvageau, Frank St‐Michael, Anna Robotham, John Kelly, Andrea Acel, Joseph D. Schrag, Majida El Bakkouri, Yves Durocher
Protein expression from stably transfected Chinese hamster ovary (CHO) clones is an established but time-consuming method for manufacturing therapeutic recombinant proteins. The use of faster, alternative approaches, such as non-clonal stable pools,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da55dfe24cf776fdd3615002431c3ff
https://doi.org/10.1002/bit.28387
https://doi.org/10.1002/bit.28387
Autor:
Mohammad P. Jamshidi, Chantelle Cairns, Simon Chong, Frank St. Michael, Evgeny V. Vinogradov, Andrew D. Cox, Janelle Sauvageau
Publikováno v:
ACS Infectious Diseases. 8:1347-1355
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cccba10277bb61bec3faf632a12da11
https://doi.org/10.1021/acsinfecdis.2c00184
https://doi.org/10.1021/acsinfecdis.2c00184
Autor:
Chantelle M. Cairns, Frank St. Michael, Mohammad Jamshidi, Henk van Faassen, Qingling Yang, Kevin A. Henry, Greg Hussack, Janelle Sauvageau, Evgeny V. Vinogradov, Andrew D. Cox
Publikováno v:
ACS Infectious Diseases. 8:1336-1346
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2c8241b610620740373f6dc8f8c81f7
https://doi.org/10.1021/acsinfecdis.2c00183
https://doi.org/10.1021/acsinfecdis.2c00183
Autor:
Neil Ravenscroft, Andrew D. Cox, Chantelle M. Cairns, Michelle M. Kuttel, Frank St. Michael, Nicole Inge Richardson
Publikováno v:
Glycoconjugate Journal. 38:735-746
Haemophilus influenzae is a leading cause of meningitis disease and mortality, particularly in young children. Since the introduction of a licensed conjugate vaccine (targeting the outer capsular polysaccharide) against the most prevalent serotype, H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd965f9d25f2850dc5177005683a3c9
https://doi.org/10.1007/s10719-021-10020-0
https://doi.org/10.1007/s10719-021-10020-0
Autor:
Eli B. Nix, Kylie Williams, Andrew D. Cox, Frank St. Michael, Sandra Romero-Steiner, Daniel S. Schmidt, William G. McCready, Marina Ulanova
Publikováno v:
Emerging Infectious Diseases, Vol 21, Iss 2, Pp 273-279 (2015)
In the post-Haemophilus influenzae type b (Hib) vaccine era that began in the 1980's, H. influenzae type a (Hia) emerged as a prominent cause of invasive disease in North American Aboriginal populations. To test whether a lack of naturally acquired a
Externí odkaz:
https://doaj.org/article/3b012ae4d1474ba2bfcd1c323cb70c8c
Autor:
Frank St. Michael, Kenneth Chisholm, Janelle Sauvageau, Mohammad P. Jamshidi, Dean Williams, Andrew D. Cox
Publikováno v:
The Journal of Organic Chemistry. 86:2184-2199
Pathogen-associated molecular patterns activate the immune system via pattern recognition receptors. Recently, newly discovered pathogen-associated molecular patterns, d-glycero-β-d-mannoheptose phosphate and d-glycero-β-d-mannoheptose 1,7-biphosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10eac2994a98b2af537b1f78d24403d7
https://doi.org/10.1021/acs.joc.0c02333
https://doi.org/10.1021/acs.joc.0c02333
Publikováno v:
Canadian Journal of Microbiology. 66:529-534
Fusobacterium nucleatum is becoming increasingly recognised as an emerging pathogen, gaining attention as a potential factor for exacerbating colorectal cancer and is strongly linked with pregnancy complications including pre-term and still births. L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::992ae5ff4ba8ee4e3c922d746476cb66
https://doi.org/10.1139/cjm-2020-0117
https://doi.org/10.1139/cjm-2020-0117
Autor:
Evgeny Vinogradov, John D. Boyce, Chantelle M. Cairns, Perry Fleming, Frank St. Michael, Andrew D. Cox, Marina Harper
Publikováno v:
Glycobiology. 31:307-314
We describe the structural characterization of the capsular polysaccharides (CPSs) of Pasteurella multocida serotypes B and E. CPS was isolated following organic solvent precipitation of the supernatant from flask grown cells. Structural analysis uti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad970a6fdb96afa3d48cafebecf0072
https://doi.org/10.1093/glycob/cwaa069
https://doi.org/10.1093/glycob/cwaa069
Autor:
Nicolas Gisch, Martin A Rossotti, Wouter F. J. Hogendorf, Susan M. Logan, Henk van Faassen, Chantelle M. Cairns, Kevin A. Henry, Annie Aubry, Greg Hussack, Andrew D. Cox, Frank St. Michael, Christian Pedersen
Publikováno v:
ACS Chemical Biology. 15:1050-1058
Clostridiodes (Clostridium) difficile is an anaerobic Gram-positive, spore-forming nosocomial, gastrointestinal pathogen causing C. difficile-associated disease with symptoms ranging from mild cases of antibiotic-associated diarrhea to fatal pseudome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e007aaae88b69d3678f4bca5a4f06124
https://doi.org/10.1021/acschembio.0c00066
https://doi.org/10.1021/acschembio.0c00066