Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Frank, Stümpel"'
Autor:
Peter Boknik, Katharina Drzewiecki, John Eskandar, Ulrich Gergs, Stephanie Grote-Wessels, Larissa Fabritz, Paulus Kirchhof, Frank U. Müller, Frank Stümpel, Wilhelm Schmitz, Norbert Zimmermann, Uwe Kirchhefer, Joachim Neumann
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Background: Adenosine can be produced in the heart and acts on cardiac adenosine receptors. One of these receptors is the A2A-adenosine receptor (A2A-AR).Methods and Results: To better understand its role in cardiac function, we generated and charact
Externí odkaz:
https://doaj.org/article/3e1b5634a372456fa8fc49a3fe8500b4
Autor:
Petra Keul, Marcel M. G. J. van Borren, Alexander Ghanem, Frank Ulrich Müller, Antonius Baartscheer, Arie O. Verkerk, Frank Stümpel, Jan Sebastian Schulte, Nazha Hamdani, Wolfgang A. Linke, Pieter van Loenen, Marek Matus, Wilhelm Schmitz, Jörg Stypmann, Klaus Tiemann, Jan‐Hindrik Ravesloot, Astrid E. Alewijnse, Sven Hermann, Léon J. A. Spijkers, Karl‐Heinz Hiller, Deron Herr, Gerd Heusch, Michael Schäfers, Stephan L. M. Peters, Jerold Chun, Bodo Levkau
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 5 (2016)
BackgroundSphingosine‐1‐phosphate plays vital roles in cardiomyocyte physiology, myocardial ischemia–reperfusion injury, and ischemic preconditioning. The function of the cardiomyocyte sphingosine‐1‐phosphate receptor 1 (S1P1) in vivo is un
Externí odkaz:
https://doaj.org/article/fbf5ff26565e41e1860b0d2d29621773
Autor:
Dennis, Glaser, Alexander, Heinick, Julius R, Herting, Fabian, Massing, Frank U, Müller, Paul, Pauls, Timofey S, Rozhdestvensky, Jan S, Schulte, Matthias D, Seidl, Boris V, Skryabin, Frank, Stümpel, Uwe, Kirchhefer
Publikováno v:
The Journal of biological chemistry. 298(9)
The activity of protein phosphatase 2A (PP2A) is determined by the expression and localization of the regulatory B-subunits. PP2A-B56α is the dominant isoform of the B'-family in the heart. Its role in regulating the cardiac response to β-adrenergi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::436e762de8cbe31141e113f5e6703535
https://pubmed.ncbi.nlm.nih.gov/35963431
https://pubmed.ncbi.nlm.nih.gov/35963431
Autor:
Dennis Glaser, Alexander Heinick, Julius R. Herting, Fabian Massing, Frank U. Müller, Paul Pauls, Timofey S. Rozhdestvensky, Jan S. Schulte, Matthias D. Seidl, Boris V. Skryabin, Frank Stümpel, Uwe Kirchhefer
Publikováno v:
Journal of Biological Chemistry. 298:102362
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2d0055d5b239db753347905a88d6f0a
https://doi.org/10.1016/j.jbc.2022.102362
https://doi.org/10.1016/j.jbc.2022.102362
Autor:
Frank U. Müller, Matthias D. Seidl, Beatrix Scholz, Boris V. Skryabin, Frank Stümpel, Juliane Stein, Kirsten Himmler
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 9 (2018)
Frontiers in Pharmacology, Vol 9 (2018)
Background: Atrial fibrillation (AF) is a significant cause of morbidity and mortality with foreseeably increasing prevalence. While large animal models of the disease are well established but resource intensive, transgenic AF mouse models are not ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780bbb1ccedea6c4d3b70ca6c88a4e67
http://europepmc.org/articles/PMC6041408
http://europepmc.org/articles/PMC6041408
Autor:
Stefan Engelhardt, Andrej Safronenko, Simone König, Igor B. Buchwalow, Frank Stümpel, Geertje Lewin, Wilhelm Schmitz, Martin J. Lohse, Sebastian Pius Rohsbach, Marek Matus, Matthias D. Seidl, Abhijit Basu, Frank Müller, Karin Frebel
Publikováno v:
Circulation. 119:79-88
Background— Chronic stimulation of the β 1 -adrenoceptor (β 1 AR) plays a crucial role in the pathogenesis of heart failure; however, underlying mechanisms remain to be elucidated. The regulation by transcription factors cAMP response element-bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae83381a0712f7e8d4ea6f396aec32e7
https://doi.org/10.1161/circulationaha.108.786533
https://doi.org/10.1161/circulationaha.108.786533
Autor:
Reinhart Kluge, Frank Stümpel, Marina Akimjanova, Klaus-Peter Knobeloch, Ivan Horak, Katharina Baumgarten, Hermann Koepsell, Hans-Georg Joost, Christina Osswald, Valentin Gorboulev
Publikováno v:
Molecular and cellular biology, 25(1): 78-87
Glucose absorption in the small intestine is essential for energy supply through carbohydrates. It is mediated by two transporters in the enterocytes, the sodium-dependent d-glucose cotransporter SGLT1 in the brush border membrane and the sodium-inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b0573cb331b61614b69f7b5edc7d92
https://doi.org/10.1128/mcb.25.1.78-87.2005
https://doi.org/10.1128/mcb.25.1.78-87.2005
Publikováno v:
Proceedings of the National Academy of Sciences. 98:11330-11335
Glucose is absorbed through the intestine by a transepithelial transport system initiated at the apical membrane by the cotransporter SGLT-1; intracellular glucose is then assumed to diffuse across the basolateral membrane through GLUT2. Here, we eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1622517449fe4f264e15dce6324aa7da
https://doi.org/10.1073/pnas.211357698
https://doi.org/10.1073/pnas.211357698
Autor:
Klaus Willecke, Goran Söhl, Ernst Peter Rieber, Kurt Jungermann, Frank Stümpel, Thomas Ott, Achim Temme
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 442:961-966
Gap junction channels in the rodent liver are composed of connexin26 (Cx26) and connexin32 (Cx32) proteins. Gap junctional intercellular communication in the mouse liver enhances the effects of hormonal or sympathetic stimulation of glucose release f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02bf335c2f862905cbe7082a88470f4d
https://doi.org/10.1007/s004240100623
https://doi.org/10.1007/s004240100623
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 277:G285-G291
In an ex situ organ perfusion system, that of the isolated nonrecirculating joint perfusion of rat small intestine and liver, insulin infused into the portal vein increased intestinal glucose absorption. This insulin action against the bloodstream ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3aec8c45be34287204af286ae487369
https://doi.org/10.1152/ajpgi.1999.277.2.g285
https://doi.org/10.1152/ajpgi.1999.277.2.g285