Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Frank, Schweizer"'
Autor:
Liam Berry, Quinn Neale, Rajat Arora, Danyel Ramirez, Marc Brizuela, Ronald Domalaon, Gilbert Arthur, Frank Schweizer
Publikováno v:
Antibiotics, Vol 13, Iss 1, p 43 (2024)
Colistin is primarily used as a last resort antibiotic against highly resistant Gram-negative bacteria (GNB). Rising rates of colistin resistance, however, may limit future use of this agent. The anthelmintic drug niclosamide has been shown to enhanc
Externí odkaz:
https://doaj.org/article/e42dabfef8674835835c44924874d5e6
Autor:
Karan Gandhi, Shiv Dhiman, Rajat Arora, Danzel Marie Ramirez, Danyel Ramirez, Gilbert Arthur, Frank Schweizer
Publikováno v:
Antibiotics, Vol 12, Iss 8, p 1261 (2023)
Metal ions, including Fe3+, affect the target site binding of some antibiotics and control the porin- and siderophore-mediated uptake of antibiotics. Amphiphilic tobramycins are an emerging class of antibiotic potentiators capable of synergizing with
Externí odkaz:
https://doaj.org/article/84ba7ad4046c446ea8415af73399ae5c
Autor:
James A. Karlowsky, Andrew J. Walkty, Melanie R. Baxter, Heather J. Adam, Philippe R. S. Lagacé-Wiens, Frank Schweizer, Denice Bay, Joseph P. Lynch, Michael R. Mulvey, George G. Zhanel
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Cefiderocol was evaluated by broth microdilution versus 1,050 highly antimicrobial-resistant Pseudomonas aeruginosa clinical isolates from the CANWARD study (2007 to 2019). Overall, 98.3% of isolates remained cefiderocol susceptible (MIC,
Externí odkaz:
https://doaj.org/article/5077a3bc87b34505b0c469eceb87ec6c
Autor:
Danyel Ramirez, Liam Berry, Ronald Domalaon, Yanqi Li, Gilbert Arthur, Ayush Kumar, Frank Schweizer
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Recently reported peptidomimetics with increased resistance to trypsin were shown to sensitize priority multidrug-resistant (MDR) Gram-negative bacteria to novobiocin and rifampicin. To further optimize proteolytic stability, β-amino acid-containing
Externí odkaz:
https://doaj.org/article/83e6e1cd95114ea296ce1175ada1d723
Autor:
Mark W Nachtigal, Paris Musaphir, Shiv Dhiman, Alon D Altman, Frank Schweizer, Gilbert Arthur
Publikováno v:
Translational Oncology, Vol 14, Iss 11, Pp 101203- (2021)
Chemotherapy resistant high grade serous ovarian cancer remains a clinically intractable disease with a high rate of mortality. We tested a novel glycosylated antitumor ether lipid called l-Rham to assess the in vitro and in vivo efficacy on high gra
Externí odkaz:
https://doaj.org/article/f1a65bf9ad1c43518cf44ad5fcf60d9f
Publikováno v:
Antibiotics, Vol 11, Iss 10, p 1277 (2022)
Polymyxins are considered a last-line treatment against infections caused by multidrug-resistant (MDR) Gram-negative bacteria. In addition to their use as a potent antibiotic, polymyxins have also been utilized as outer membrane (OM) permeabilizers,
Externí odkaz:
https://doaj.org/article/39e23cd261fe44efbeac028fca25e60e
Publikováno v:
ACS Infectious Diseases. 9:864-885
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72a07d6d3720b3206021f8638ed7e400
https://doi.org/10.1021/acsinfecdis.2c00549
https://doi.org/10.1021/acsinfecdis.2c00549
Publikováno v:
Antibiotics, Vol 11, Iss 3, p 335 (2022)
Outer membrane (OM) drug impermeability typically associated with a molecular weight above 600 Da and high hydrophobicity prevents accumulation of many antibiotics in Gram-negative bacteria (GNB). Previous studies have shown that ultrashort tetrabasi
Externí odkaz:
https://doaj.org/article/25ac085738264e8a95c735bcbcbd445c
Publikováno v:
Electrochemistry Communications, Vol 119, Iss , Pp 106825- (2020)
Electrochemical sensing of antibiotics is important to assess environmental contamination. Due to the emergence of drug-resistant bacteria alternative medication, such as hybrid drug compounds are being developed. The present study reports a comprehe
Externí odkaz:
https://doaj.org/article/591e405641894bbea5b1c016ca2c051f
Autor:
Ayodeji O. Oriola, Adetunji J. Aladesanmi, Thomas O. Idowu, Ezekiel O. Akinkunmi, Adebola O. Oyedeji, Makanjuola O. Ogunsina, Gilbert Arthur, Frank Schweizer
Publikováno v:
Chemistry Africa. 5:1959-1966
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29edddfedcfa52251d7e68dd5f480ed2
https://doi.org/10.1007/s42250-022-00488-0
https://doi.org/10.1007/s42250-022-00488-0