Zobrazeno 1 - 10
of 338
pro vyhledávání: '"Frank, Rösch"'
Autor:
Tilman Läppchen, Adrianna Bilinska, Eirinaios Pilatis, Elena Menéndez, Surachet Imlimthan, Euy Sung Moon, Ali Afshar-Oromieh, Frank Rösch, Axel Rominger, Eleni Gourni
Publikováno v:
Molecules, Vol 29, Iss 13, p 3093 (2024)
Background: FAP radiopharmaceuticals show promise for cancer diagnosis; however, their limited tumor residency hinders treatment. This study compared two FAPi derivatives, DOTA.SA.FAPi and DOTAGA.(SA.FAPi)2, labeled with gallium-68 and lutetium-177,
Externí odkaz:
https://doaj.org/article/285d4217cb994469b1b11d23d67b90fa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Cell based therapies are evolving as an effective new approach to treat various diseases. To understand the safety, efficacy, and mechanism of action of cell-based therapies, it is imperative to follow their biodistribution noninvasively. Po
Externí odkaz:
https://doaj.org/article/a7a2496301474d7d928456833ddee2d0
Autor:
Frank Rösch
This work is conceived to meet the demand of state-of-the-art literature to teach the fundamentals as well as the modern applications of nuclear chemistry. The work will consist of two volumes: the first one covering the basics of nuclear chemistry s
Autor:
Jean-Philippe Sinnes, Ulrike Bauder-Wüst, Martin Schäfer, Euy Sung Moon, Klaus Kopka, Frank Rösch
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-11 (2020)
Abstract Background The AAZTA chelator and in particular its bifunctional derivative AAZTA5 was recently investigated to demonstrate unique capabilities to complex diagnostic and therapeutic trivalent radiometals under mild conditions. This study pre
Externí odkaz:
https://doaj.org/article/d1a2d3b0fd9c4b479ae97266b454021c
Autor:
Michael Hofstetter, Euy Sung Moon, Fabio D’Angelo, Lucien Geissbühler, Ian Alberts, Ali Afshar-Oromieh, Frank Rösch, Axel Rominger, Eleni Gourni
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-19 (2020)
Abstract Background Gastrin Releasing Peptide receptor (GRPr)-based radioligands have shown great promise for diagnostic imaging of GRPr-positive cancers, such as prostate and breast. The present study aims at developing and evaluating a versatile GR
Externí odkaz:
https://doaj.org/article/4a0fe7b14d8f475ab34e7db297ebd9f2
Autor:
Euy Sung Moon, Filipe Elvas, Gwendolyn Vliegen, Stef De Lombaerde, Christel Vangestel, Sven De Bruycker, An Bracke, Elisabeth Eppard, Lukas Greifenstein, Benedikt Klasen, Vasko Kramer, Steven Staelens, Ingrid De Meester, Pieter Van der Veken, Frank Rösch
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-20 (2020)
Abstract Background Fibroblast activation protein (FAP) is a proline selective serine protease that is overexpressed in tumor stroma and in lesions of many other diseases that are characterized by tissue remodeling. In 2014, a most potent FAP-inhibit
Externí odkaz:
https://doaj.org/article/6eef6de76ec3424eabc82ef799f24e24
Autor:
Florian Rosar, Hans-Georg Buchholz, Sebastian Michels, Manuela A. Hoffmann, Markus Piel, Christopher M. Waldmann, Frank Rösch, Stefan Reuss, Mathias Schreckenberger
Publikováno v:
EJNMMI Physics, Vol 7, Iss 1, Pp 1-17 (2020)
Abstract Background 44Sc has been increasingly investigated as a potential alternative to 68Ga in the development of tracers for positron emission tomography (PET). The lower mean positron energy of 44Sc (0.63 MeV) compared to 68Ga (0.83 MeV) can res
Externí odkaz:
https://doaj.org/article/c7f7458b7f394c2cb0b0c2c49ca6420c
Autor:
Frank Rösch
Publikováno v:
Zeitschrift für Didaktik der Biologie - Biologie Lehren und Lernen, Vol 25 (2021)
Außerschulisches Lernen wird nicht nur als sinnvolle Bereicherung, sondern auch als wesentliche Ergänzung von Biologieunterricht in Fachräumen oder Klassenzimmern angesehen. Kompetenzförderlich gestaltet und auch die Entwicklung von Einstellungen
Externí odkaz:
https://doaj.org/article/31459fba29a0495fbcec42d447d69289
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 4, Iss 1, Pp 1-10 (2019)
Abstract Purpose AAZTA (1,4-bis (carboxymethyl)-6-[bis (carboxymethyl)]amino-6-methylperhydro-1,4-diazepine) based chelators were initially developed in the context of magnetic resonance imaging. First radiochemical studies showed the capability of A
Externí odkaz:
https://doaj.org/article/5c3750d7fc0b4121bfa8fc4812a25e44
Autor:
Patricia E. Edem, Jean-Philippe Sinnes, Stefanie Pektor, Nicole Bausbacher, Raffaella Rossin, Abdolreza Yazdani, Matthias Miederer, Andreas Kjær, John F. Valliant, Marc S. Robillard, Frank Rösch, Matthias M. Herth
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-8 (2019)
Abstract Background Pretargeted imaging allows the use of short-lived radionuclides when imaging the accumulation of slow clearing targeting agents such as antibodies. The biotin-(strept)avidin and the bispecific antibody-hapten interactions have bee
Externí odkaz:
https://doaj.org/article/3c3a2b2c7f3b4c0690ccc0893c5a719d