Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Frank, Petersen"'
Autor:
Junping Yin, Admar Verschoor, Xiaoyang Yue, Torsten Goldmann, Harald Heidecke, Gabriela Riemekasten, Frank Petersen, Xinhua Yu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAutoantibody-mediated complement activation plays an essential role in a variety of autoimmune disorders. However, the role of complement in systemic sclerosis (SSc) remains largely unknown. In this study, we aimed to determine the role o
Externí odkaz:
https://doaj.org/article/30cc61615da846b1a32d9144855a8d8f
Autor:
Robert E. Bruccoleri, Edward J. Oakeley, Ann Marie E. Faust, Marc Altorfer, Sophie Dessus-Babus, David Burckhardt, Mevion Oertli, Ulrike Naumann, Frank Petersen, Joanne Wong
Publikováno v:
GigaByte (2023)
Irises are perennial plants, representing a large genus with hundreds of species. While cultivated extensively for their ornamental value, commercial interest in irises lies in the secondary metabolites present in their rhizomes. The Dalmatian Iris (
Externí odkaz:
https://doaj.org/article/c68bc30b7c3148eb8f21765f0f38316e
Autor:
Kai Yang, Junping Yin, Xiaoyang Yue, Katja Bieber, Gabriela Riemekasten, Ralf J. Ludwig, Frank Petersen, Xinhua Yu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionNatural products have been shown to an important source of therapeutics for human disease. In this study, we aimed to identify natural compounds as potential therapeutics for epidermolysis bullosa acquisita (EBA), an autoimmune disease ca
Externí odkaz:
https://doaj.org/article/fdb0c8100d0b4ef1ab5a9de8512905b1
Autor:
Longyu Shan, Liang Zhang, Xiaolei Zhu, Zhilin Wang, Shaohan Fang, Junfeng Lin, Jianweng Wang, Ning Li, Hongming Liu, Xiaowen Zhang, Yihui Feng, Jingwei Liu, Jianyun Pan, Guanzhi Ye, Xiuyi Yu, Amanda Tufman, Alexander Katalinic, Torsten Goldmann, Frank Petersen, Jie Jiang, Guojun Geng, Xinhua Yu
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Background Lung cancers arising in never smokers have been suggested to be substantially different from lung cancers in smokers at an epidemiological, genetic and molecular level. Focusing on non-small cell lung cancer (NSCLC), we characteri
Externí odkaz:
https://doaj.org/article/6c078706266844d085cbeee7a7a70c7c
Autor:
Yaqing Shu, Xiaoyang Yue, Jacqueline Wax, Brigitte Kasper, Junping Yin, Xiaoqing Wang, Liang Zhang, Marjan Ahmadi, Harald Heidecke, Antje Müller, Peter Lamprecht, Xinhua Yu, Gabriela Riemekasten, Frank Petersen
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-12 (2022)
Abstract Background Recently, a novel humanized mouse model for systemic sclerosis (SSc) was established by transferring peripheral blood mononuclear cells (PBMC) from patients with SSc to Rag2 −/− Il2rg −/− immunodeficient mice. Here, we aim
Externí odkaz:
https://doaj.org/article/cef05a485b1b4f778de006f7750dc260
Autor:
Kathrin Buntin, Peter Ertl, Dominic Hoepfner, Philipp Krastel, Edward Oakeley, Dominik Pistorius, Tim Schumann, Joanne Wong, Frank Petersen
Publikováno v:
CHIMIA, Vol 75, Iss 7/8, Pp 620-634 (2021)
Natural Products (NPs) are molecular' special equipment ' that impart survival benefits on their producers in nature. Due to their evolved functions to modulate biology these privileged metabolites are substantially represented in the drug market and
Externí odkaz:
https://doaj.org/article/244242ec12ab4eefa9fecbb8f0374fc1
Autor:
Brigitte Kasper, Xiaoyang Yue, Torsten Goldmann, Askin Gülsen, Christian Kugler, Xinhua Yu, Frank Petersen
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundIn-vitro models of differentiated primary human airway epithelial cells are a valuable tool to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Through the use of these models, it has been shown that the express
Externí odkaz:
https://doaj.org/article/aea427eda2d449609e2d46ac8018d677
Autor:
Guangdong Wang, Aiping Ma, Liang Zhang, Jiaxi Guo, Qun Liu, Frank Petersen, Zhanxiang Wang, Xinhua Yu
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Acute exacerbations show a significant impact on disease morbidity and mortality in chronic obstructive pulmonary disease (COPD). In contrast to stable COPD, the association of smoking status with clinical and laboratory characteristics in patients w
Externí odkaz:
https://doaj.org/article/274312205a8d4d489ec35f265baa8b83
Autor:
Yaqing Shu, Dan He, Xiaoyu Ma, Jianfang Li, Haotian Wu, Chen Chen, Zhengqi Lu, Frank Petersen, Wei Qiu, Xinhua Yu
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 2, Pp 498-503 (2021)
Abstract Paraneoplastic autoimmune encephalitis (PAE) represents a group of rare neurological syndromes associated with neoplastic diseases. Here, we report a case that multiple anti‐neuronal antibodies were present in a patient with PAE who develo
Externí odkaz:
https://doaj.org/article/61c76066b7284eb3967edf739ee3b9da
Autor:
Sho Hiroyasu, Matthew R. Zeglinski, Hongyan Zhao, Megan A. Pawluk, Christopher T. Turner, Anika Kasprick, Chiharu Tateishi, Wataru Nishie, Angela Burleigh, Peter A. Lennox, Nancy Van Laeken, Nick J. Carr, Frank Petersen, Richard I. Crawford, Hiroshi Shimizu, Daisuke Tsuruta, Ralf J. Ludwig, David J. Granville
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Pemphigoid diseases involve autoimmune mediated blistering and immunopathology of the upper dermis. Here, the authors implicate granzyme B in the immunopathology in multiple in vivo models of pemphigoid diseases and utilise a topical granzyme B inhib
Externí odkaz:
https://doaj.org/article/e1fcb0e4655740288ff9814e14e03085