Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Frank, Lynch"'
Autor:
Frank Lynch
Publikováno v:
CODEE Journal. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40afb719cb8b6442958f831bc1d35809
https://doi.org/10.5642/codee.202215.01.02
https://doi.org/10.5642/codee.202215.01.02
Autor:
Heeringa Katharine, Allison R. Greenplate, Meredith Perpetua, Randall J. Brezski, Gregory Bannish, Robert Jordan, Frank Lynch, Stephen G. McCarthy, Katharine D. Grugan, Michelle Kinder, William R. Strohl, Keri L. Soring
Publikováno v:
Journal of Biological Chemistry. 288:30843-30854
Molecularly engineered antibodies with fit-for-purpose properties will differentiate next generation antibody therapeutics from traditional IgG1 scaffolds. One requirement for engineering the most appropriate properties for a particular therapeutic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ac0b3bd9a3b0710d27bc695d73ab29
https://doi.org/10.1074/jbc.m113.486142
https://doi.org/10.1074/jbc.m113.486142
Autor:
Nambi Aiyar, Diane Naselsky, Zhaohui Ao, Christopher L Herold, Frank Lynch, Stephen A. Douglas, Jyoti Disa
Publikováno v:
British Journal of Pharmacology. 142:921-932
1 In an effort to identify endogenous, native mammalian urotensin-II (U-II) receptors (UT), a diverse range of human, primate and rodent cell lines (49 in total) were screened for the presence of detectable [125I]hU-II binding sites. 2 UT mRNA (North
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e519430918a9e1dc2ccb774cfdc5a8ed
https://doi.org/10.1038/sj.bjp.0705743
https://doi.org/10.1038/sj.bjp.0705743
Publikováno v:
Experimental Cell Research. 287:39-46
dUTP nucleotidohydrolase (dUTPase) catalyzes the hydrolysis of dUTP to dUMP and pyrophosphate and is the central regulator of cellular dUTP pools. Nuclear (DUT-N) and mitochondrial (DUT-M) isoforms of the protein have been identified in humans and ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99af1f5ac8ece990a2b9fe5fcbef5a8
https://doi.org/10.1016/s0014-4827(03)00048-x
https://doi.org/10.1016/s0014-4827(03)00048-x
Autor:
Susan J. Muller, Mary C. Kosciuk, Robert D. Ladner, Frank Lynch, Sal Caradonna, Michael J Hansbury
Publikováno v:
Experimental Cell Research. 222:345-359
Evidence is presented on two forms of uracil-DNA glycosylase (UDG1 and UDG2) that exist in human cells. We have developed an affinity technique to isolate uracil-DNA glycosylases from HeLa cells. This technique relies on the use of a uracil-DNA glyco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e84815435b60352a097feb69ab8e17
https://doi.org/10.1006/excr.1996.0044
https://doi.org/10.1006/excr.1996.0044
Autor:
Steve Bernstein, Frank Lynch
Publikováno v:
Molecular Pathology in Drug Discovery and Development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::594dbefdb44ea80d2cc215973971257c
https://doi.org/10.1002/9780470475959.ch9
https://doi.org/10.1002/9780470475959.ch9
Publikováno v:
Validation of Cell-Based Assays in the GLP Setting: A Practical Guide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6947209c9db85d05bbc97ed191729ea2
https://doi.org/10.1002/9780470987810.ch5
https://doi.org/10.1002/9780470987810.ch5
Autor:
Stephen A, Douglas, Diane, Naselsky, Zhaohui, Ao, Jyoti, Disa, Christopher L, Herold, Frank, Lynch, Nambi V, Aiyar
Publikováno v:
British journal of pharmacology. 142(6)
1 In an effort to identify endogenous, native mammalian urotensin-II (U-II) receptors (UT), a diverse range of human, primate and rodent cell lines (49 in total) were screened for the presence of detectable [125I]hU-II binding sites. 2 UT mRNA (North
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d9ab1761a6a390c6f249883eca28876
https://pubmed.ncbi.nlm.nih.gov/15210573
https://pubmed.ncbi.nlm.nih.gov/15210573
Publikováno v:
Blood. 124:5588-5588
MF is a neoplastic stem cell disorder in which a multipotent hematopoietic stem cell acquires a clonal proliferative advantage, and its progeny inappropriately releases fibrogenic factors into the bone marrow microenvironment, leading to secondary bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31ebebe2a5ba5be3fa5957bfbcaa7cf1
https://doi.org/10.1182/blood.v124.21.5588.5588
https://doi.org/10.1182/blood.v124.21.5588.5588
Publikováno v:
Journal of pediatric surgery. 35(11)
Whether laparoscopic appendectomy (LA) is superior to open appendectomy (OA) for simple (SA) and perforated appendicitis (PA) in children is debatable. The operative experience of 4 senior pediatric surgeons at a single institution was studied over a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9704313a9b707e799acaf3c213caab8
https://pubmed.ncbi.nlm.nih.gov/11083428
https://pubmed.ncbi.nlm.nih.gov/11083428