Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Frank, Koentgen"'
Autor:
Virginie Lam, Ryusuke Takechi, Mark J Hackett, Roslyn Francis, Michael Bynevelt, Liesl M Celliers, Michael Nesbit, Somayra Mamsa, Frank Arfuso, Sukanya Das, Frank Koentgen, Maree Hagan, Lincoln Codd, Kirsty Richardson, Brenton O'Mara, Rainer K Scharli, Laurence Morandeau, Jonathan Gauntlett, Christopher Leatherday, Jan Boucek, John C L Mamo
Publikováno v:
PLoS Biology, Vol 19, Iss 9, p e3001358 (2021)
Several lines of study suggest that peripheral metabolism of amyloid beta (Aß) is associated with risk for Alzheimer disease (AD). In blood, greater than 90% of Aß is complexed as an apolipoprotein, raising the possibility of a lipoprotein-mediated
Externí odkaz:
https://doaj.org/article/540be8eaf710424384e6a5c34c3f0831
Autor:
Jasmin Barman-Aksözen, Paulina C´wiek, Vijay B. Bansode, Frank Koentgen, Judith Trüb, Pawel Pelczar, Paolo Cinelli, Xiaoye Schneider-Yin, Daniel Schümperli, Elisabeth I. Minder
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 3, Pp 225-233 (2017)
Erythropoietic protoporphyria (EPP) is caused by deficiency of ferrochelatase (FECH), which incorporates iron into protoporphyrin IX (PPIX) to form heme. Excitation of accumulated PPIX by light generates oxygen radicals that evoke excessive pain and,
Externí odkaz:
https://doaj.org/article/82087eb4bf224a71a8c100020e20c040
Progranulin overexpression in sensory neurons attenuates neuropathic pain in mice: Role of autophagy
Autor:
Christine Altmann, Stefanie Hardt, Caroline Fischer, Juliana Heidler, Hee-Young Lim, Annett Häussler, Boris Albuquerque, Béla Zimmer, Christine Möser, Christian Behrends, Frank Koentgen, Ilka Wittig, Mirko H.H. Schmidt, Albrecht M. Clement, Thomas Deller, Irmgard Tegeder
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 294-311 (2016)
Peripheral or central nerve injury is a frequent cause of chronic pain and the mechanisms are not fully understood. Using newly generated transgenic mice we show that progranulin overexpression in sensory neurons attenuates neuropathic pain after sci
Externí odkaz:
https://doaj.org/article/9ec104a5bf194e04889a56a8d4d4324b
Autor:
Richard A. Lake, Bruce W.S. Robinson, Frank Koentgen, Amanda Sherwood, Melissa Dunham, Amanda Segal, Ivonne van Bruggen, Cleo Robinson
Although it has been clear for >40 years that mesothelioma can be caused by asbestos, not all patients with this disease have a history of asbestos exposure. Other factors, including non-asbestos fibers and ionizing radiation, are known to cause mali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c8acb91b670e14d5ebc6b85a471464
https://doi.org/10.1158/0008-5472.c.6494792.v1
https://doi.org/10.1158/0008-5472.c.6494792.v1
Autor:
Richard A. Lake, Bruce W.S. Robinson, Frank Koentgen, Amanda Sherwood, Melissa Dunham, Amanda Segal, Ivonne van Bruggen, Cleo Robinson
Supplementary Tables 2-3 from A Novel SV40 TAg Transgenic Model of Asbestos-Induced Mesothelioma: Malignant Transformation Is Dose Dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c80f32c8bc7775fa1506690354783f
https://doi.org/10.1158/0008-5472.22365632.v1
https://doi.org/10.1158/0008-5472.22365632.v1
Autor:
Himanshu Kharkwal, Farhat Batool, Frank Koentgen, David R Bell, David A Kendall, Francis J P Ebling, Ian R Duce
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0187959 (2017)
Cytochrome P450 4x1 (Cyp4x1) is expressed at very high levels in the brain but the function of this protein is unknown. It has been hypothesised to regulate metabolism of fatty acids and to affect the activity of endocannabinoid signalling systems, w
Externí odkaz:
https://doaj.org/article/a951ee8c28ec47a3ba7837f898eaae29
Autor:
Sumasri Guntupalli, Pojeong Park, Dae Hee Han, Mitchell Ringuet, Daniel G. Blackmore, Dhanisha J. Jhaveri, Frank Koentgen, Jocelyn Widagdo, Bong-Kiun Kaang, Victor Anggono
SUMMARYActivity-dependent changes in the number of AMPA-type glutamate receptors (AMPARs) at the synapse underpin the expression of long-term potentiation (LTP) and long-term depression (LTD), cellular correlates of learning and memory. Post-translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8860d7a88bee2192acf6566ab70c1dcf
https://doi.org/10.1101/2022.07.27.501670
https://doi.org/10.1101/2022.07.27.501670
Autor:
Yao Zhang, Yajun Cheng, Gert H. Hansen, Lise-Lotte Niels-Christiansen, Frank Koentgen, Lena Ohlsson, Åke Nilsson, Rui-Dong Duan
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 4, Pp 771-781 (2011)
Alkaline sphingomyelinase (alk-SMase) hydrolyses sphingomyelin (SM) to ceramide in the gut. To evaluate the physiological importance of the enzyme, we generated alk-SMase knockout (KO) mice by the Cre-recombinase-Locus of X-over P1(Cre-LoxP) system a
Externí odkaz:
https://doaj.org/article/a6b8a592c1864bd6a66997baae041f0a
Autor:
Roslyn J. Francis, Christopher Leatherday, Michael Bynevelt, Jan Boucek, Maree Hagan, Jonathan Gauntlett, Virginie Lam, Sukanya Das, Kirsty L. Richardson, Brenton O’Mara, Rainer K. Scharli, Liesl Celliers, Michael Nesbit, Laurence Morandeau, John C.L. Mamo, Frank Arfuso, Frank Koentgen, Somayra Mamsa, Ryusuke Takechi, Lincoln Codd, Mark J. Hackett
Publikováno v:
PLoS Biology
PLoS Biology, Vol 19, Iss 9, p e3001358 (2021)
PLoS Biology, Vol 19, Iss 9, p e3001358 (2021)
Several lines of study suggest that peripheral metabolism of amyloid beta (Aß) is associated with risk for Alzheimer disease (AD). In blood, greater than 90% of Aß is complexed as an apolipoprotein, raising the possibility of a lipoprotein-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b0bc7a2375b9169cb7868628e24f71
http://europepmc.org/articles/PMC8439475
http://europepmc.org/articles/PMC8439475
Autor:
Frank Koentgen, John M. Mariadason, Holly Anderton, Laura J. Jenkins, Rebecca Nightingale, Fiona H Tan, Kael Schoffer, Matthias Ernst, Oliver M. Sieber, Charbel Darido, Amardeep S. Dhillon, Michael Chopin, Camilla M. Reehorst, David S. Williams, Ian Y. Luk, Moritz F. Eissmann, Dmitri Mouradov, Michael Buchert
Publikováno v:
Development. 148
Ets homologous factor (EHF) is a member of the epithelial-specific Ets (ESE) family of transcription factors. To investigate its role in development and epithelial homeostasis, we generated a series of novel mouse strains in which the Ets DNA-binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa0f225dfd97dd519fc0ed9bbe86eaf
https://doi.org/10.1242/dev.199542
https://doi.org/10.1242/dev.199542