Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Frank, Hirth"'
Publikováno v:
PLoS Biology, Vol 21, Iss 8, p e3002273 (2023)
Miro GTPases control mitochondrial morphology, calcium homeostasis, and regulate mitochondrial distribution by mediating their attachment to the kinesin and dynein motor complex. It is not clear, however, how Miro proteins spatially and temporally in
Externí odkaz:
https://doaj.org/article/8adb3f1bd8334d4694551562e0c7be52
Autor:
Lucy Granat, Debbra Y Knorr, Daniel C Ranson, Emma L Hamer, Ram Prosad Chakrabarty, Francesca Mattedi, Laura Fort-Aznar, Frank Hirth, Sean T Sweeney, Alessio Vagnoni, Navdeep S Chandel, Joseph M Bateman
Publikováno v:
PLoS Genetics, Vol 19, Iss 7, p e1010793 (2023)
Mutations in subunits of the mitochondrial NADH dehydrogenase cause mitochondrial complex I deficiency, a group of severe neurological diseases that can result in death in infancy. The pathogenesis of complex I deficiency remain poorly understood, an
Externí odkaz:
https://doaj.org/article/720dde159eb94f2e9971e386d99fd3c0
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Insects are ectothermal animals that are constrained in their survival and reproduction by external temperature fluctuations which require either active avoidance of or movement towards a given heat source. In Drosophila, different thermorec
Externí odkaz:
https://doaj.org/article/0aaea794aeb948d5b26e08e59be028b0
Autor:
Catarina Gonçalves-Pimentel, David Mazaud, Benjamin Kottler, Sandra Proelss, Frank Hirth, Manolis Fanto
Publikováno v:
F1000Research, Vol 9 (2020)
Invertebrate glia performs most of the key functions controlled by mammalian glia in the nervous system and provides an ideal model for genetic studies of glial functions. To study the influence of adult glial cells in ageing we have performed a gene
Externí odkaz:
https://doaj.org/article/c5d7cf7797964fbdb59ab190747534cf
Autor:
Catarina Gonçalves-Pimentel, David Mazaud, Benjamin Kottler, Sandra Proelss, Frank Hirth, Manolis Fanto
Publikováno v:
F1000Research, Vol 9 (2020)
Invertebrate glia performs most of the key functions controlled by mammalian glia in the nervous system and provides an ideal model for genetic studies of glial functions. To study the influence of adult glial cells in ageing we have performed a gene
Externí odkaz:
https://doaj.org/article/4084f46b3ef34e169ff017f4186b55bd
Publikováno v:
Biology Open, Vol 8, Iss 7 (2019)
The ellipsoid body (EB) of the Drosophila central complex mediates sensorimotor integration and action selection for adaptive behaviours. Insights into its physiological function are steadily accumulating, however the developmental origin and genetic
Externí odkaz:
https://doaj.org/article/0b9b7f64ef1545e09bccff0668df12d7
Autor:
Helen C. Schuster, Frank Hirth
Publikováno v:
Science Advances. 9
Conserved cis-regulatory elements (CREs) control Engrailed -, Pax2 -, and dachshund -related gene expression networks directing the formation and function of corresponding midbrain circuits in arthropods and vertebrates. Polarized outgroup analyses o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9db473a447c17c354ad8d1b6804643a8
https://doi.org/10.1126/sciadv.ade8259
https://doi.org/10.1126/sciadv.ade8259
Autor:
Jessika C. Bridi, Frank Hirth
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Parkinson's disease (PD) is characterized by intracellular inclusions of aggregated and misfolded α-Synuclein (α-Syn), and the loss of dopaminergic (DA) neurons in the brain. The resulting motor abnormalities mark the progression of PD, while non-m
Externí odkaz:
https://doaj.org/article/161f2c8bada94c549086d29dddd86a38
Publikováno v:
Science (New York, N.Y.). 378(6622)
For more than a century, the origin and evolution of the arthropod head and brain have eluded a unifying rationale reconciling divergent morphologies and phylogenetic relationships. Here, clarification is provided by the fossilized nervous system of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2c75f289debe486c28362cd331b4059
https://pubmed.ncbi.nlm.nih.gov/36423278
https://pubmed.ncbi.nlm.nih.gov/36423278
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 11 (2017)
The central complex in the insect brain is a composite of midline neuropils involved in processing sensory cues and mediating behavioral outputs to orchestrate spatial navigation. Despite recent advances, however, the neural mechanisms underlying sen
Externí odkaz:
https://doaj.org/article/823105aa5f3345ad85bcd82c36412554