Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Frank, Donath"'
Autor:
Michael Boettcher, Gerd Mikus, Dietmar Trenk, Hans‐Dirk Düngen, Frank Donath, Nikos Werner, Mahir Karakas, Nina Besche, Dominik Schulz‐Burck, Mireille Gerrits, James Hung, Corina Becker
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 5, Pp 1204-1214 (2022)
Abstract Vericiguat was developed for the treatment of symptomatic chronic heart failure (HF) in adult patients with reduced ejection fraction who are stabilized after a recent decompensation event. Guidelines recommend long‐acting nitrates, such a
Externí odkaz:
https://doaj.org/article/802eb1a41f814307a5c64af6075f3e09
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background Lozenges containing lidocaine and cetylpyridinium chloride (CPC) are commonly used for the treatment of sore throat. The lidocaine acts locally to provide pain relief and the CPC has an antiseptic effect. Mebucaine CL, a well-esta
Externí odkaz:
https://doaj.org/article/8c70bf95ea3547a18584e4d58e00f1a7
Autor:
Michael Böttcher, Hans-Dirk Düngen, Vasile Corcea, Frank Donath, Rainard Fuhr, Pim Gal, Gerd Mikus, Dietmar Trenk, Martin Coenen, Philippe Vieira Pires, Claudia Maschke, Antonios Othon Aliprantis, Nina Besche, Corina Becker
Publikováno v:
American Journal of Cardiovascular Drugs. 23:145-155
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12410062f25b14292c7d70a0ce3b4628
https://doi.org/10.1007/s40256-022-00557-2
https://doi.org/10.1007/s40256-022-00557-2
Autor:
André Warnke, Frank Donath, Ralph-Steven Wedemeyer, Maren Richter, Andreas Horstmann, Claudia Peschel
Publikováno v:
International Journal of Clinical Pharmacology and Therapeutics
Objectives To establish the relative bioavailability and to assess bioequivalence of oral, immediate-release tablets containing pridinol and to determine the pharmacokinetic properties of the compound. Methods and materials In this single-center, ope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3132f0da6c845b472d43b549cb52b49
https://doi.org/10.5414/cp203900
https://doi.org/10.5414/cp203900
Autor:
Hildegard Sourgens, Katharina Erb-Zohar, Gerd Mikus, Frank Donath, Kerstin Breithaupt-Groegler, Stephanie Plassmann, Jens Rengelshausen, Georg Wensing, Timothy C. Hardman
Publikováno v:
Therapeutic Innovation & Regulatory Science
Purpose A discussion forum was hosted by the Association for Applied Human Pharmacology (AGAH e.V.) to critically debate how to interpret and optimise the Investigator’s Brochure (IB) for meaningful risk assessment of early clinical trials. Materia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371232e0b364d853672206a9bd809a26
http://europepmc.org/articles/PMC7857342
http://europepmc.org/articles/PMC7857342
Autor:
Alessandro Comandini, Alessandra Del Vecchio, Henning Blume, Alessandro Ruggieri, Marina Todorova-Sanjari, Fabrizio Calisti, Ralph-Steven Wedemeyer, Patrizia Dragone, André Warnke, Frank Donath, Agnese Cattaneo, Maria Teresa Rosignoli, Rossella Picollo
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 59:71-86
Objectives To establish dose proportionality for trazodone and gabapentin at fixed ratios of trazodone/gabapentin 2.5/25, 10/100, and 30/300 and investigation of potential drug-drug interaction at a dose of 10/100. Materials and methods 29 out of 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81969352a36165889ad8569ae5c8c7a4
https://doi.org/10.5414/cp203845
https://doi.org/10.5414/cp203845
Autor:
Alessandra Del Vecchio, Barbara Schug, Maria Teresa Rosignoli, Rossella Picollo, Fabio Garofolo, Valeria Tellone, Ralph-Steven Wedemeyer, Patrizia Dragone, Fabrizio Calisti, Frank Donath, Alessandro Comandini
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 58:583-594
Objectives To establish the relative bioavailability between a newly developed oral gel and a marketed oral lyophilisate-containing rizatriptan benzoate. Materials and methods A total of 47 out of 48 healthy subjects, aged 34 ± 10 (SD) years and bod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7960d36635f5e5d4923a1c721512b42
https://doi.org/10.5414/cp203652
https://doi.org/10.5414/cp203652
Autor:
Michael Boettcher, Hans‐Dirk Düngen, Frank Donath, Gerd Mikus, Nikos Werner, Petra A. Thuermann, Mahir Karakas, Nina Besche, Tanja Koch, Matthias Gurniak, Corina Becker
Publikováno v:
Clinical pharmacology and therapeutics. 111(6)
Vericiguat is a soluble guanylate cyclase stimulator indicated to reduce the risk of cardiovascular death and heart failure (HF) hospitalization in adults with symptomatic chronic HF and ejection fraction less than 45%. Guidelines recommend short-act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0154b06d4f1cb4e7b3fca5e92ad8da6
https://pubmed.ncbi.nlm.nih.gov/35258101
https://pubmed.ncbi.nlm.nih.gov/35258101
Autor:
Christian Knopke, Ulrike Hanke, Marco Neumann, Christian Brätter, Werner Weitschies, Felix Schneider, Mirko Koziolek, Christiane Schiller, Barbara Schug, Knut Seidlitz, Claudia Heimhardt, Hanshermann Franke, Rudy Thoma, Frank Donath, Anschütz M
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 338
More than 50 years ago, the first gastroretentive dosage forms came up. Since then, no practical and at the same time reliable gastroretentive system is available on market. A major obstacle in the development of novel gastroretentive systems is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c2ba0fb814f9dce9f3a09cf3c3bfb2
https://pubmed.ncbi.nlm.nih.gov/34416321
https://pubmed.ncbi.nlm.nih.gov/34416321
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-8 (2018)
Trials
Trials
Background Lozenges containing lidocaine and cetylpyridinium chloride (CPC) are commonly used for the treatment of sore throat. The lidocaine acts locally to provide pain relief and the CPC has an antiseptic effect. Mebucaine CL, a well-established f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e72d774fe1a7d91e6d6aaef338d06e
http://link.springer.com/article/10.1186/s13063-018-3077-6
http://link.springer.com/article/10.1186/s13063-018-3077-6