Zobrazeno 1 - 10
of 384
pro vyhledávání: '"Frank, Brombacher"'
Autor:
Julius E. Chia, Robert P. Rousseau, Mumin Ozturk, Sibongiseni K. L. Poswayo, Rodney Lucas, Frank Brombacher, Suraj P. Parihar
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionForkhead box P3 (Foxp3) T regulatory cells are critical for maintaining self-tolerance, immune homeostasis, and regulating the immune system.MethodsWe investigated interleukin-4 receptor alpha (IL-4Rα) signalling on T regulatory cells (T
Externí odkaz:
https://doaj.org/article/01834e39e29940b1a605b05bd814cedb
Autor:
Kensuke Miyake, Junya Ito, Kazufusa Takahashi, Jun Nakabayashi, Frank Brombacher, Shigeyuki Shichino, Soichiro Yoshikawa, Sachiko Miyake, Hajime Karasuyama
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Both monocytes and macrophages are heterogeneous populations. It was traditionally understood that Ly6Chi classical (inflammatory) monocytes differentiate into pro-inflammatory Ly6Chi macrophages. Accumulating evidence has suggested that Ly6
Externí odkaz:
https://doaj.org/article/b71abb01b4404290a3a8f7955fcbff5b
Autor:
Paballo Mosala, Thabo Mpotje, Nada Abdel Aziz, Hlumani Ndlovu, Fungai Musaigwa, Justin Komguep Nono, Frank Brombacher
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Schistosomiasis remains the most devastating neglected tropical disease, affecting over 240 million people world-wide. The disease is caused by the eggs laid by mature female worms that are trapped in host’s tissues, resulting in chronic Th2 driven
Externí odkaz:
https://doaj.org/article/9d90f103c08e4ebaa2b8f2b3c4cb4805
Autor:
Martyna Scibiorek, Nontobeko Mthembu, Sandisiwe Mangali, Amkele Ngomti, Paul Ikwegbue, Frank Brombacher, Sabelo Hadebe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Atopic dermatitis (AD) is a common pruritic inflammatory skin disease with complex environmental and genetic predisposing factors. Primary skin barrier dysfunction and aberrant T helper 2 (TH2) responses to common allergens, together with in
Externí odkaz:
https://doaj.org/article/df8d5b84d81f4fa19f362f39f5d2b736
Autor:
Jonadab E. Olguín, Edmundo Corano-Arredondo, Victoria Hernández-Gómez, Irma Rivera-Montoya, Mario A. Rodríguez, Itzel Medina-Andrade, Berenice Arendse, Frank Brombacher, Luis I. Terrazas
Publikováno v:
Pathogens, Vol 13, Iss 2, p 169 (2024)
To determine the role that the IL-4/IL13 receptor plays in the development of alternatively activated macrophages (AAM or M2) and their role in the regulation of immunity to the extraintestinal phase of the helminth parasite Taenia crassiceps, we fol
Externí odkaz:
https://doaj.org/article/cf002de4209b44d487e4f4e4070bb836
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
C57BL/6 mice are one of the most widely used inbred strains in biomedical research. Early separation of the breeding colony has led to the development of several sub-strains. Colony separation led to genetic variation development driving numerous phe
Externí odkaz:
https://doaj.org/article/f010e2c6c96544c6a552334f63c9fde1
Autor:
Nathan Scott Kieswetter, Mumin Ozturk, Shelby-Sara Jones, Sibusiso Senzani, Melissa Dalcina Chengalroyen, Frank Brombacher, Bavesh Kana, Reto Guler
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 1227-1238 (2021)
Peptidoglycan (PG), a heteropolysaccharide component of the mycobacterial cell wall can be shed during tuberculosis infection with immunomodulatory consequences. As such, changes in PG structure are expected to have important implications on disease
Externí odkaz:
https://doaj.org/article/08f6f056b8d54a79871dccbc1bc15e0d
Autor:
Shelby-Sara Jones, Mumin Ozturk, Nathan Scott Kieswetter, Sibongiseni K. L. Poswayo, Rudranil Hazra, Ousman Tamgue, Suraj P. Parihar, Harukazu Suzuki, Frank Brombacher, Reto Guler
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Lymphoblastic leukemia 1 (Lyl1) is a well-studied transcription factor known to exhibit oncogenic potential in various forms of leukemia with pivotal roles in hematopoietic stem cell biology. While its role in early hematopoiesis is well established,
Externí odkaz:
https://doaj.org/article/08648511b9a8434fabf9104a87c56cf1
Autor:
Martyna Scibiorek, Nontobeko Mthembu, Sandisiwe Mangali, Amkele Ngomti, Paul Ikwegbue, Frank Brombacher, Sabelo Hadebe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/0efa612852aa4a6ea2946503dc7ffd2a
Autor:
Sonika Patial, Brandon W. Lewis, Thao Vo, Ishita Choudhary, Kshitiz Paudel, Yun Mao, Dhruthi Singamsetty, Frank Brombacher, Yogesh Saini
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Increased eosinophil recruitment is a hallmark feature of eosinophilic disorders. Here, we delineated the key molecular and cellular players involved in physiological eosinophilic recruitment during normal postnatal lung development in mice.
Externí odkaz:
https://doaj.org/article/bf37f5aa6f554468883adc4d66eedd11