Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Frank' Gabel"'
Autor:
Lucía Álvarez, Kevin Haubrich, Louisa Iselin, Laurent Gillioz, Vincenzo Ruscica, Karine Lapouge, Sandra Augsten, Ina Huppertz, Nila Roy Choudhury, Bernd Simon, Pawel Masiewicz, Mathilde Lethier, Stephen Cusack, Katrin Rittinger, Frank Gabel, Alexander Leitner, Gracjan Michlewski, Matthias W. Hentze, Frédéric H. T. Allain, Alfredo Castello, Janosch Hennig
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract TRIM25 is an RNA-binding ubiquitin E3 ligase with central but poorly understood roles in the innate immune response to RNA viruses. The link between TRIM25’s RNA binding and its role in innate immunity has not been established. Thus, we ut
Externí odkaz:
https://doaj.org/article/d8245675d28e4b2bbc482fdb79f08563
Autor:
Matthias Richter, Laura Hoffmann, Frank Gabel, Johannes Stephan, Jan Gehrmann, Ananda Stullich, Olaf Ballaschke, Sylvia Berlin, Florian Finke, Anastasia Grossmann, Claudia Gruhner, Kathleen Kaminski, Andreas Seemann
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Introduction Rates of incapacity to work due to mental disorders have increased in many European countries. The consequences of persistent stress can impact individuals’ physical and psychological well-being and gradually develop into chronic stres
Externí odkaz:
https://doaj.org/article/841aca7a0af24037a77a14c78da63db0
Autor:
Marco Zaccaria, William Dawson, Darius Russel Kish, Massimo Reverberi, Maria Carmela Bonaccorsi di Patti, Marek Domin, Viviana Cristiglio, Bun Chan, Luca Dellafiora, Frank Gabel, Takahito Nakajima, Luigi Genovese, Babak Momeni
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract We investigate laccase-mediated detoxification of aflatoxins, fungal carcinogenic food contaminants. Our experimental comparison between two aflatoxins with similar structures (AFB1 and AFG2) shows significant differences in laccase-mediated
Externí odkaz:
https://doaj.org/article/1c6defa54d2749e59f9b936659937501
Autor:
Nataliya Danilenko, Lukas Lercher, John Kirkpatrick, Frank Gabel, Luca Codutti, Teresa Carlomagno
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Histone chaperones have been shown to control the activity and specificity of histone-modifying enzymes. Here the authors establish a structural model of the acetyltransferase Rtt109 in complex with Asf1 and Vps75 and the histone dimer H3:H4, finding
Externí odkaz:
https://doaj.org/article/0b7982cadac74428b575ac9e21c9f021
Publikováno v:
IUCrJ, Vol 6, Iss 4, Pp 521-525 (2019)
Small-angle X-ray scattering (SAXS) is increasingly used to extract structural information from a multitude of soft-matter and biological systems in aqueous solution, including polymers, detergents, lipids, colloids, proteins and RNA/DNA. When SAXS d
Externí odkaz:
https://doaj.org/article/31ed1913000a401bacd089d638dba04b
Autor:
Amedeo Amedei, Fatemeh Asadzadeh, Francesco Papi, Maria Giuliana Vannucchi, Veronica Ferrucci, Iris A. Bermejo, Marco Fragai, Carolina Vieira De Almeida, Linda Cerofolini, Stefano Giuntini, Mauro Bombaci, Elisa Pesce, Elena Niccolai, Francesca Natali, Eleonora Guarini, Frank Gabel, Chiara Traini, Stefano Catarinicchia, Federica Ricci, Lorenzo Orzalesi, Francesco Berti, Francisco Corzana, Massimo Zollo, Renata Grifantini, Cristina Nativi
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101250- (2020)
Summary: The Tn antigen is a well-known tumor-associated carbohydrate determinant, often incorporated in glycopeptides to develop cancer vaccines. Herein, four copies of a conformationally constrained mimetic of the antigen TnThr (GalNAc-Thr) were co
Externí odkaz:
https://doaj.org/article/a64cb7cea1e64b2e969ea4bafe958a4e
Publikováno v:
eLife, Vol 9 (2020)
2’-O-rRNA methylation, which is essential in eukaryotes and archaea, is catalysed by the Box C/D RNP complex in an RNA-guided manner. Despite the conservation of the methylation sites, the abundance of site-specific modifications shows variability
Externí odkaz:
https://doaj.org/article/25d8a60e8a9548a784a10a4c61c1ee04
Autor:
Hamed Kooshapur, Nila Roy Choudhury, Bernd Simon, Max Mühlbauer, Alexander Jussupow, Noemi Fernandez, Alisha N. Jones, Andre Dallmann, Frank Gabel, Carlo Camilloni, Gracjan Michlewski, Javier F. Caceres, Michael Sattler
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
hnRNP A1 is an auxiliary factor that promotes the Microprocessor-mediated processing of pri-mir-18a, of the oncomiR-1 cluster. Here the authors employ an integrative structural biology approach and provide insights into the molecular mechanism of how
Externí odkaz:
https://doaj.org/article/014a6dc8990b44dca7c25370f4266456
Autor:
Frank Gabel
Publikováno v:
Small Angle Scattering Part B: Methods for Structural Interpretation ISBN: 9780323991810
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::764138db1d8689858d1ff9cbd7431d4b
https://doi.org/10.1016/bs.mie.2022.09.016
https://doi.org/10.1016/bs.mie.2022.09.016
Autor:
Francesca Caporaletti, Zuzanna Pietras, Vivian Morad, Lars-Göran Mårtensson, Frank Gabel, Björn Wallner, Anne Martel, Maria Sunnerhagen
Publikováno v:
Biophysical journal 122(2), 408-418 (2023). doi:10.1016/j.bpj.2022.11.2949
Biophysical journal 122(2), 408 - 418 (2023). doi:10.1016/j.bpj.2022.11.2949
In this work, we used small-angle x-ray and neutron scattering to reveal the shape of the protein-DNA complex of the Pseudomonas aeruginosa transcriptional regulator Me
In this work, we used small-angle x-ray and neutron scattering to reveal the shape of the protein-DNA complex of the Pseudomonas aeruginosa transcriptional regulator Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828eeb540b0fc3764324f2f6c6de5083