Engineered lentivirus-derived nanoparticles (LVNPs) for delivery of CRISPR/Cas ribonucleoprotein complexes supporting base editing, prime editing and in vivo gene modification.

Autor: Haldrup J; Department of Biomedicine, Aarhus University, Aarhus C, Denmark., Andersen S; Department of Biomedicine, Aarhus University, Aarhus C, Denmark., Labial ARL; Department of Biomedicine, Aarhus University, Aarhus C, Denmark., Wolff JH; Department of Biomedicine, Aarhus University, Aarhus C, Denmark., Frandsen FP; Department of Biomedicine, Aarhus University, Aarhus C, Denmark., Skov TW; Department of Biomedicine, Aarhus University, Aarhus C, Denmark., Rovsing AB; Department of Biomedicine, Aarhus University, Aarhus C, Denmark., Nielsen I; Department of Biomedicine, Aarhus University, Aarhus C, Denmark., Jakobsen TS; Department of Biomedicine, Aarhus University, Aarhus C, Denmark.; Department of Ophthalmology, Aarhus University Hospital, Aarhus N, Denmark., Askou AL; Department of Biomedicine, Aarhus University, Aarhus C, Denmark.; Department of Ophthalmology, Aarhus University Hospital, Aarhus N, Denmark., Thomsen MK; Department of Biomedicine, Aarhus University, Aarhus C, Denmark., Corydon TJ; Department of Biomedicine, Aarhus University, Aarhus C, Denmark.; Department of Ophthalmology, Aarhus University Hospital, Aarhus N, Denmark., Thomsen EA; Department of Biomedicine, Aarhus University, Aarhus C, Denmark., Mikkelsen JG; Department of Biomedicine, Aarhus University, Aarhus C, Denmark.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2023 Oct 13; Vol. 51 (18), pp. 10059-10074.