Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Francys Alarcon"'
Autor:
Lina Zelinger, Charmeine Ko, Francys Alarcon, Samuel Koo, Kenneth Thomas, Hyunjun Nam, Fernando Lopez Diaz, Segun Jung, Fei Ye, Shashikant Kulkarni
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100109- (2023)
Externí odkaz:
https://doaj.org/article/b8d2249ccede4bd8bcf779e33c1c6d7b
Autor:
Lina Zelinger, Samuel Koo, Francys Alarcon, Charmeine Ko, Brad B Thomas, Segun C Jung, Ying Wang, Fei Ye, Shashikant Kulkarni
Publikováno v:
Blood. 140:11870-11871
Abstract 219: Single-tube NGS profiling allows identification of molecular signature in ALL patients
Autor:
Lina Zelinger, Samuel Koo, Charmeine Ko, Francys Alarcon, Kenneth B. Thomas, Segun C. Jung, Fernando J. Lopez Diaz, Fei Ye, Shashikant Kulkarni
Publikováno v:
Cancer Research. 83:219-219
Background: Acute lymphoblastic leukemia (ALL) can be classified to subtypes by molecular signatures correlating to prognosis and treatment regimen, making accurate molecular profiling of interest for both clinical and research communities. NGS techn
Autor:
Fei Ye, Tibor Gyuris, Samuel Koo, Christophe Magnan, Ryan Bender, Brad B Thomas, Sally Agersborg, Archana Ramesh, Vincent Funari, Fernando J. Lopez-Diaz, Abhisek Ghosal, Hyunjun Nam, Paris Petersen, Francys Alarcon, Rudy Fabunan, Segun C Jung, Soo Jin Kang
Publikováno v:
Blood. 138:4925-4925
Background: Paired-box Pax gene family protein 5 (PAX5)/B-cell specific activator protein (BSAP) is a transcription factor encoded by the PAX5 gene and has an essential role in B-cell differentiation and maturation. High PAX5 expression is detected e
Autor:
Soo Jin Kang, Francys Alarcon, Fernando J. Lopez-Diaz, Tibor Gyuris, Hyunjun Nam, Samuel Koo, Archana Ramesh, Rudy Fabunan, Vincent Funari, Paris Petersen, Sally Agersborg, Christophe Magnan, Ryan Bender, Segun C Jung, Abhisek Ghosal, Fei Ye, Brad B Thomas
Publikováno v:
Blood. 138:1875-1875
Background: Acute Lymphocytic Leukemia (ALL) is the most common childhood cancer and accounts for about a quarter of adult acute leukemias. Current NCCN recommendations for clinical testing for risk stratification and treatment guidance include karyo
Autor:
Samuel Koo, Paris Petersen, Hyunjun Nam, Susan Yamahata, Sally Agersborg, Francys Alarcon, Christophe Magnan, Fernando J. Lopez-Diaz, Rudy Fabunan, Tibor Gyuris, Brad B Thomas, Archana Ramesh, Ryan Bender, Soo Jin Kang, Fei Ye, Vincent Funari, Segun C Jung, Abhisek Ghosal
Publikováno v:
Blood. 138:2961-2961
Background: Multiple myeloma (MM) is a blood cancer type affecting plasma cell in bone marrow. MM is heterogenous in nature but t(11;14)(q13;q32) translocation is a common prognostic marker among MM patients. One of the most frequent oncogenic driver
Autor:
Lauryn Keeler, Christophe Magnan, Yongxin Yu, Shiping Jiang, Eve Shinbrot, Vincent Funari, Segun C Jung, Yanglong Mou, Fei Ye, Hyunjun Nam, Tessa Weiss, Ryan Bender, Brad B Thomas, Lawrence M. Weiss, Francys Alarcon, Sally Agersborg
Publikováno v:
Blood. 136:29-30
Background: A cost effective and comprehensive genomic profiling (CGP) approach for diagnosis, risk stratification and therapy would be useful for the evaluation of oncologic specimens. Available approaches involving additive testing for DNA and RNA
Autor:
Brad B Thomas, Christophe Magnan, Francys Alarcon, Fei Ye, Eve Shinbrot, Vincent Funari, Segun C Jung, Sally Agersborg, Yanglong Mou, Cynthie Wong, Ryan Bender, Lawrence M. Weiss, Tibor Gyuris
Publikováno v:
Cancer Research. 81:2208-2208
Background: To comprehensively profile mutations in hematologic malignancies, we developed a targeted multimodal NGS assay that can detect SNVs, InDels, fusions, gene expression, and copy number variations from total nucleic acid (TNA) in a single tu