Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Francoise Meylan"'
Autor:
Vivienne Edwards, Dylan L. Smith, Francoise Meylan, Linda Tiffany, Sarah Poncet, Wells W. Wu, Je-Nie Phue, Luis Santana-Quintero, Kathleen A. Clouse, Odile Gabay
Publikováno v:
Microorganisms, Vol 10, Iss 1, p 73 (2021)
Very little is known about disease transmission via the gut microbiome. We hypothesized that certain inflammatory features could be transmitted via the gut microbiome and tested this hypothesis using an animal model of inflammatory diseases. Twelve-w
Externí odkaz:
https://doaj.org/article/77d7967ba7f449dd8307aa062beac131
Autor:
Aran Son, Francoise Meylan, Julio Gomez-Rodriguez, Zenia Kaul, McKella Sylvester, Guido H. Falduto, Estefania Vazquez, Tamara Haque, Moses M. Kitakule, Chujun Wang, Kalpana Manthiram, Chen-Feng Qi, Jun Cheng, Rama K. Gurram, Jinfang Zhu, Pamela Schwartzberg, Joshua D. Milner, Pamela A. Frischmeyer-Guerrerio, Daniella M. Schwartz
Publikováno v:
Nature Immunology. 24:1036-1048
Autor:
Taylor K Farley, Nathan Richoz, Sarah Lamberth, Peter Gregersen, Fabio Cominelli, Francoise Meylan, Richard M. Siegel
Publikováno v:
The Journal of Immunology. 198:201.1-201.1
The TNF-family cytokine TL1A (TNF-like ligand 1A) signaling through its receptor DR3 (Death Receptor 3) promotes immunopathology in diverse autoimmune disease models by facilitating T cell accumulation and Innate Lymphoid Cell activation at the site
Autor:
Nathan Richoz, Taylor K. Farley, Samantha A. Chalmers, Chaim Putterman, Francoise Meylan, Menna R. Clatworthy, Richard M. Siegel
Publikováno v:
The Journal of Immunology. 198:63.11-63.11
Systemic lupus erythematosus is a polygenic autoimmune disease with a broad spectrum of clinical manifestations including organ-threatening kidney inflammation associated with immune complex (IC) deposition. The kidney is populated by a rich network
Autor:
Francoise Meylan, Erika Hayes, John Ferdinand, Taylor Farley, Nathan Richoz, Odile Gabay, Richard M Siegel
Publikováno v:
The Journal of Immunology. 196:49.2-49.2
DR3 (Tnsfrsf25) is a death domain-containing tumor necrosis factor receptor found primarily on activated T cells and innate lymphocytes. Interaction with its ligand the TNF-family cytokine TL1A plays critical roles in diverse autoimmune disease model
Autor:
Julio Washington Gomez-Rodriguez, Francoise Meylan, Robin Handon, Erika Hayes, Stacie Anderson, Martha Kirby, Richard M Siegel, Pamela L Schwartzberg
Publikováno v:
The Journal of Immunology. 196:133.35-133.35
T helper 9 (Th9) cells produce IL-9, a cytokine implicated in allergic asthma and autoimmunity. We show that Itk, a mediator of T-cell receptor signalling in Th2 immune responses and the development of asthma, is a positive regulator of Th9 different
Autor:
Julio Gomez-Rodriguez, Francoise Meylan, Robin Handon, Erika Hayes, Richard Siegel, Pamela Schwartzberg
Publikováno v:
The Journal of Immunology. 194:201.18-201.18
One of the main functions of the adaptive immune system is to mount specific responses to pathogens. These effector CD4 T helper cells, include Th1, Th2, Th9 and Th17 cells, produce distinct cytokines important in the eradication of different infecti
Autor:
Yun-Jeong Song, In Ah. Choi, Françoise Meylan, M. Kristen Demoruelle, Taylor Farley, Arianne C. Richard, Eric Hawley, John Botson, Yoo Jin Hong, Eun Young Lee, Sabina R. Mian, Bartlett C. Hamilton, Geoffrey M. Thiele, Ted R. Mikuls, Naveen Gara, Chris D. Ward, Sarah Lamberth, Kevin D. Deane, Theo Heller, Michael M. Ward, David M. Lee, Thi-Sau Migone, William Stohl, James R. O’Dell, Jill M. Norris, V. Michael Holers, Peter Gregersen, Yeong-Wook Song, Richard M. Siegel
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-14 (2020)
Abstract Background The tumor necrosis factor (TNF) superfamily cytokine TNF-like protein 1A (TL1A) and its receptor DR3 are essential for diverse animal models of autoimmune disease and may be pathogenic in rheumatoid arthritis (RA). However, the re
Externí odkaz:
https://doaj.org/article/67eda1b4a8ed453b9815ed1b537021d9
The TNF family member TL1A promotes Th9 differentiation and Th9-mediated immunopathology (LYM3P.733)
Autor:
Arianne Richard, Cuiyan Tan, Eric Hawley, Julio Gomez-Rodriguez, Ritobrata Goswami, Xiangping Yang, Anthony Cruz, Pallavi Penumetcha, Erika Hayes, Martin Pelletier, Odile Gabay, Matthew Walsh, John Ferdinand, Andrea Keane-Myers, Yongwon Choi, John O'Shea, Aymen Al-Shamkhani, Mark Kaplan, Igal Gery, Richard Siegel, Francoise Meylan
Publikováno v:
The Journal of Immunology. 192:64.7-64.7
The TNF family cytokine TL1A (Tnfsf15) costimulates T cells through its receptor DR3 (Tnfrsf25). Currently known effects of TL1A on T cell differentiation or systemic immune responses cannot account for the resistance of Tnfrsf25-/- mice to diverse a
Publikováno v:
The Journal of Immunology. 192:115.2-115.2
The Tumour Necrosis Factor Superfamily (TNFSF) are an important source of costimulatory signals required for activation of T cells. The TNFSF is composed of 29 receptors and 18 ligands; one such pair is Death receptor 3 (DR3) and TNF-like ligand 1A (