Výsledky vyhledávání - "Francois Rouzaud"

Wear behavior and in vitro cytotoxicity of wear debris generated from hydroxyapatite-carbon nanotube composite coating

Autor: Arvind Agarwal, Anup Kumar Keshri, Jonathan Solomon, Ana Paula Benaduce, Debrupa Lahiri, Francois Rouzaud, Lidia Kos

Publikováno v: Journal of Biomedical Materials Research Part A. :1-12

This work evaluates the effect of carbon nanotube (CNT) addition to plasma-sprayed hydroxyapatite (HA) coating on its tribological behavior, biocompatibility of the coating, and cytotoxicity of CNT-containing wear debris. Biological response of the C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8db96dac0582566538672db3022630e
https://doi.org/10.1002/jbm.a.32952

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Boron nitride nanotube reinforced polylactide–polycaprolactone copolymer composite: Mechanical properties and cytocompatibility with osteoblasts and macrophages in vitro

Autor: Debrupa Lahiri, Francois Rouzaud, Srinivasa R. Bakshi, Lidia Kos, Arvind Agarwal, Anup Kumar Keshri, Tanisha Richard

Publikováno v: Acta Biomaterialia. 6:3524-3533

Biodegradable polylactide-polycaprolactone copolymer (PLC) has been reinforced with 0, 2 and 5wt.% boron nitride nanotubes (BNNTs) for orthopedic scaffold application. Elastic modulus of the PLC-5wt.% BNNT composite, evaluated through nanoindentation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa311f76c55017776d4a38a2069160f
https://doi.org/10.1016/j.actbio.2010.02.044

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Carbon Nanotube Reinforced Polylactide−Caprolactone Copolymer: Mechanical Strengthening and Interaction with Human Osteoblasts in Vitro

Autor: James J. Valdés, Francois Rouzaud, Arvind Agarwal, Lidia Kos, Debrupa Lahiri, Nikolaos M. Tsoukias, Shabnam M. Namin, Anup Kumar Keshri

Publikováno v: ACS Applied Materials & Interfaces. 1:2470-2476

This study proposes the use of carbon nanotubes (CNTs) as reinforcement to enhance the mechanical properties of a polylactide-caprolactone copolymer (PLC) matrix. Biological interaction of PLC-CNT composites with human osteoblast cells is also invest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e7c4a7f0a8dd339c62df53a73b434c
https://doi.org/10.1021/am900423q

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Voluntary exercise prevents the obese and diabetic metabolic syndrome of the melanocortin‐4 receptor knockout mouse

Autor: Amy Andreasen, Glenn A. Walter, Kim R. Haskell, Lorraine M. Koerper, William J. Millard, Sally A. Litherland, Henry V. Baker, Francois Rouzaud, Marcus C. Moore, Carrie Haskell-Luevano, Jay W. Schaub, Zhimin Xiang

Publikováno v: The FASEB Journal. 23:642-655

Exercise is a mechanism for maintenance of body weight in humans. Morbidly obese human patients have been shown to possess single nucleotide polymorphisms in the melanocortin-4 receptor (MC4R). MC4R knockout mice have been well characterized as a gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9850c80b6f513e8768465fb9b2f48112
https://doi.org/10.1096/fj.08-109686

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Involvement of Dynein and Spectrin with Early Melanosome Transport and Melanosomal Protein Trafficking

Autor: Masayuki Nakamura, Toshihiko Hoashi, Yuji Yamaguchi, Yoko Kawa, Elodie Le Pape, Vincent J. Hearing, Masako Mizoguchi, Hidenori Watabe, Francois Rouzaud, Julio C. Valencia

Publikováno v: Journal of Investigative Dermatology. 128(1):162-174

Melanosomes are unique membrane-bound organelles specialized for the synthesis and distribution of melanin. Mechanisms involved in the trafficking of proteins to melanosomes and in the transport of mature pigmented melanosomes to the dendrites of mel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca35076a1500c3d4bd15f6c8dcb18fd

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Dickkopf 1 (DKK1) regulates skin pigmentation and thickness by affecting Wnt/ β‐catenin signaling in keratinocytes

Autor: Francois Rouzaud, Yuji Yamaguchi, Vincent J. Hearing, Toru Miki, Thierry Passeron, Ichiro Katayama, Hidenori Watabe, Chiharu Tohyama, Takahiko Hara, Toshihiko Hoashi, Ken Ichi Yasumoto

Publikováno v: The FASEB Journal. 22:1009-1020

The epidermis (containing primarily keratinocytes and melanocytes) overlies the dermis (containing primarily fibroblasts) of human skin. We previously reported that dickkopf 1 (DKK1) secreted by fibroblasts in the dermis elicits the hypopigmented phe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0671fdb74790bf2e5ab82574226c76
https://doi.org/10.1096/fj.07-9475com

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Evaluation of simple and Cost-Effective DNA preparation and subsequent PCR amplification for clinically relevant mycobacteria

Autor: Francois Rouzaud, Jaime Robledo, Verónica Gomez, Diego H. Cáceres, Gloria Isabel Mejía, Angela Guzmán

Publikováno v: Repositorio UdeA
Universidad de Antioquia
instacron:Universidad de Antioquia

Aim: Slow growth rate in culture renders the traditional isolation, identification, and drug susceptibility testing of clinically important mycobacteria inadequate when there is an urgent need for a precise diagnosis in order to initiate patient trea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71161ac3b29466c6710e0151eb8c66e5

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Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas

Autor: Jill K. Paterson, Michael M. Gottesman, Julio C. Valencia, Vincent J. Hearing, Richard D. Leapman, Susan H. Garfield, Francois Rouzaud, Barry Lai, Kevin G. Chen, Guofeng Zhang, Stephen Wincovitch, Werner Berens

Publikováno v: Proceedings of the National Academy of Sciences. 103:9903-9907

Multidrug resistance mechanisms underlying the intractability of malignant melanomas remain largely unknown. In this study, we demonstrate that the development of multidrug resistance in melanomas involves subcellular sequestration of intracellular c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edf4376434dbe8ea457444c3b259c8b
https://doi.org/10.1073/pnas.0600213103

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Sorting of Pmel17 to melanosomes through the plasma membrane by AP1 and AP2: evidence for the polarized nature of melanocytes

Autor: Yuji Yamaguchi, Hidenori Watabe, Julio C. Valencia, Vincent J. Hearing, Ettore Appella, An Chi, Kevin G. Chen, Kaoruko Takahashi, Jeffrey Shabanowitz, Wilfred D. Vieira, Werner Berens, Francois Rouzaud, Kunio Nagashima, Donald F. Hunt

Publikováno v: Journal of Cell Science. 119:1080-1091

Adaptor proteins (AP) play important roles in the sorting of proteins from the trans-Golgi network, but how they function in the sorting of various melanosome-specific proteins such as Pmel17, an essential structural component of melanosomes, in mela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc262a7ef306a62cbc660cee0cef431
https://doi.org/10.1242/jcs.02804

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Mutations in dopachrome tautomerase (Dct) affect eumelanin/pheomelanin synthesis, but do not affect intracellular trafficking of the mutant protein

Autor: Kazumasa Wakamatsu, Francisco Solano, M. Lynn Lamoreux, Shosuke Ito, Gertrude-E. Costin, Adina L. Milac, Yuji Yamaguchi, Vincent J. Hearing, Andrei J. Petrescu, Francois Rouzaud, Wilfred D. Vieira, Julio C. Valencia

Publikováno v: Biochemical Journal. 391:249-259

Dopachrome tautomerase (Dct) is a type I membrane protein and an important regulatory enzyme that plays a pivotal role in the biosynthesis of melanin and in the rapid metabolism of its toxic intermediates. Dct-mutant melanocytes carrying the slaty or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3878d2d5853a9dd04d031d38ca2d76e7
https://doi.org/10.1042/bj20042070

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