Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Francois Leu"'
Autor:
Amélie Joly, Jean-Louis Thoumas, Anne Lambert, Estelle Caillon, François Leulier, Filipe De Vadder
Publikováno v:
Nutrition & Metabolism, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Dysregulation of energy metabolism, including hyperglycemia, insulin resistance and fatty liver have been reported in a substantial proportion of lean children. However, non-obese murine models recapitulating these features are lacking to st
Externí odkaz:
https://doaj.org/article/cae283d4c8d14be3b8ae1814a81f4bf1
Autor:
Nikos Nikolopoulos, Renata C. Matos, Pascal Courtin, Isabel Ayala, Houssam Akherraz, Jean-Pierre Simorre, Marie-Pierre Chapot-Chartier, François Leulier, Stéphanie Ravaud, Christophe Grangeasse
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Teichoic acids (TA) are crucial for the homeostasis of the bacterial cell wall as well as their developmental behavior and interplay with the environment. TA can be decorated by different modifications, modulating thus their biochemical prop
Externí odkaz:
https://doaj.org/article/53451fccc05043adb34d0ea06fbea3ed
Autor:
Théodore Grenier, Jessika Consuegra, Mariana G Ferrarini, Houssam Akherraz, Longwei Bai, Yves Dusabyinema, Isabelle Rahioui, Pedro Da Silva, Benjamin Gillet, Sandrine Hughes, Cathy I Ramos, Renata C Matos, François Leulier
Publikováno v:
eLife, Vol 12 (2023)
Symbiotic bacteria interact with their host through symbiotic cues. Here, we took advantage of the mutualism between Drosophila and Lactiplantibacillus plantarum (Lp) to investigate a novel mechanism of host-symbiont interaction. Using chemically def
Externí odkaz:
https://doaj.org/article/2892f1c0218a4a9b835e34884fc61204
Autor:
Nikos Nikolopoulos, Renata C Matos, Stephanie Ravaud, Pascal Courtin, Houssam Akherraz, Simon Palussiere, Virginie Gueguen-Chaignon, Marie Salomon-Mallet, Alain Guillot, Yann Guerardel, Marie-Pierre Chapot-Chartier, Christophe Grangeasse, François Leulier
Publikováno v:
eLife, Vol 12 (2023)
Metazoans establish mutually beneficial interactions with their resident microorganisms. However, our understanding of the microbial cues contributing to host physiology remains elusive. Previously, we identified a bacterial machinery encoded by the
Externí odkaz:
https://doaj.org/article/bb047dfb9dd14a47a0862102288dcadf
Autor:
Marion Darnaud, Filipe De Vadder, Pascaline Bogeat, Lilia Boucinha, Anne-Laure Bulteau, Andrei Bunescu, Céline Couturier, Ana Delgado, Hélène Dugua, Céline Elie, Alban Mathieu, Tereza Novotná, Djomangan Adama Ouattara, Séverine Planel, Adrien Saliou, Dagmar Šrůtková, Jennifer Yansouni, Bärbel Stecher, Martin Schwarzer, François Leulier, Andrea Tamellini
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Here, the authors develop and characterize a mouse microbiota composed of 15 strains representative of the intestinal microbiota found in C57BL/6J specific opportunistic- and pathogen-free (C57Bl/6J SOPF) mice and derive a new standardized gnotobioti
Externí odkaz:
https://doaj.org/article/ad2f54703d4e4a40b40755a7d77374ec
Approaches to discern if microbiome associations reflect causation in metabolic and immune disorders
Autor:
Marijana Basic, Dominique Dardevet, Peter Michael Abuja, Silvia Bolsega, Stéphanie Bornes, Robert Caesar, Francesco Maria Calabrese, Massimo Collino, Maria De Angelis, Philippe Gérard, Miguel Gueimonde, François Leulier, Eva Untersmayr, Evelien Van Rymenant, Paul De Vos, Isabelle Savary-Auzeloux
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Our understanding of microorganisms residing within our gut and their roles in the host metabolism and immunity advanced greatly over the past 20 years. Currently, microbiome studies are shifting from association and correlation studies to studies de
Externí odkaz:
https://doaj.org/article/8dace665075d45fcb8a597916270aa58
Autor:
Grégoire Chevalier, Eleni Siopi, Laure Guenin-Macé, Maud Pascal, Thomas Laval, Aline Rifflet, Ivo Gomperts Boneca, Caroline Demangel, Benoit Colsch, Alain Pruvost, Emeline Chu-Van, Aurélie Messager, François Leulier, Gabriel Lepousez, Gérard Eberl, Pierre-Marie Lledo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The gut microbiota may contribute to depression, but the underlying mechanism is not well understood. Here the authors use a mouse model of stress induced depression to demonstrate that behavioural changes conferred by fecal transplant from stressed
Externí odkaz:
https://doaj.org/article/161cd6205c514a068009fecb2385aea8
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/c96eb70d0d49479bbc0e5f30b36c5710
Autor:
Dali Ma, Maroun Bou-Sleiman, Pauline Joncour, Claire-Emmanuelle Indelicato, Michael Frochaux, Virginie Braman, Maria Litovchenko, Gilles Storelli, Bart Deplancke, François Leulier
Publikováno v:
iScience, Vol 19, Iss , Pp 436-447 (2019)
Summary: Eukaryotic genomes encode several buffering mechanisms that robustly maintain invariant phenotypic outcome despite fluctuating environmental conditions. Here we show that the Drosophila gut-associated commensals, represented by a single facu
Externí odkaz:
https://doaj.org/article/717b08a23ff34195b8d976e5dd76f49e
Autor:
Jessika Consuegra, Théodore Grenier, Houssam Akherraz, Isabelle Rahioui, Hugo Gervais, Pedro da Silva, François Leulier
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101232- (2020)
Summary: The gut microbiota shapes animal growth trajectory in stressful nutritional environments, but the molecular mechanisms behind such physiological benefits remain poorly understood. The gut microbiota is mostly composed of bacteria, which cons
Externí odkaz:
https://doaj.org/article/895d8421077a458a871e72f09a432f6b