Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Francois J. G. Vingerhoets"'
Publikováno v:
Annals of Neurology. 41:58-64
Clinical scales, based on the major signs of Parkinson's disease (PD), are commonly used to assess the effect of symptomatic treatment of PD. With the appearance of therapy aiming to rescue or protect the nigrostriatal neurons in PD, it becomes essen
Autor:
Francois J. G. Vingerhoets, G. Michael Nauert, Donald A. Smith, Cesario V. Borlongan, Thomas B. Freeman, Douglas A. Holt, Robert A. Hauser, Barry J. Snow, Lisa Gauger, Donald B. Calne, Paul R. Sanberg, C. Warren Olanow, Jeffrey H. Kordower
Publikováno v:
Annals of Neurology. 38:379-388
We performed fetal nigral transplantations in 4 Parkinson's disease (PD) patients. Solid grafts were bilaterally implanted into the postcommissural putamen using 3 to 4 donors per side aged 6 1/2 to 9 weeks postconception. Transplant deposits were se
Publikováno v:
Clinics in Chest Medicine. 15:729-737
SUMMARY Respiratory function depends on numerous neurologic structures, the organization of which extends from the cerebral cortex to the medulla. The study of patients who have had strokes has allowed deductions about this organization, and various
Publikováno v:
European Neurology. 34:1-3
Autor:
D. B. Calne, Joseph K.C. Tsui, Ryan J. Uitti, Chong S. Lee, Hitoshi Shinotoh, Michael Schulzer, Francois J. G. Vingerhoets
Publikováno v:
Neurology. 48(5)
Increased glutamatergic transmission in the basal ganglia is implicated in the pathophysiology of idiopathic parkinsonism (IP). We investigated the effects of lamotrigine (LTG), a glutamate-release inhibitor, in the symptomatic treatment of IP in two
Autor:
Asha Kishore, D. B. Calne, M. Wijker, Barry J. Snow, Zbigniew K. Wszolek, R. de la Fuente-Fernandez, Francois J. G. Vingerhoets, F. Arwert, Michael Schulzer
Publikováno v:
Neurology. 47(6)
Pallido-ponto-nigral degeneration (PPND) is a dominantly inherited disorder with parkinsonism. We performed PET with [18F]fluorodopa (FD) and, later, gene testing in 12 asymptomatic relatives at risk from a family with PPND and compared the striatal
Autor:
Kellie A. Hewitt, D. B. Calne, Hitoshi Shinotoh, C. W. Olanow, M F Beal, Paul F. Good, Daniel P. Perl, Francois J. G. Vingerhoets, Barry J. Snow
Publikováno v:
Neurology. 46(2)
We gave three adult rhesus monkeys seven IV injections of manganese chloride at approximately 1-week intervals. We evaluated neurologic status by serial clinical examinations and performed a levodopa test if the animal developed features of basal gan
Autor:
Francois J. G. Vingerhoets, K.R. Buckley, Michael J. Adam, Barry J. Snow, James E. Holden, B. Legg, G.L-Y. Chan, Salma Jivan, Thomas J. Ruth, S. Morrison, Vesna Sossi
Publikováno v:
Quantification of Brain Function Using PET
This chapter demonstrates the graphical analysis of 6-fluorodopa (6-FD) with the time course in cortex as the input function to discriminate strongly between those with Parkinson's disease and normal subjects. However, this uptake measure is biased d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5d87279c17e4fcd4ef9a5363bfe0df2
https://doi.org/10.1016/b978-012389760-2/50047-5
https://doi.org/10.1016/b978-012389760-2/50047-5
Autor:
Francois J. G. Vingerhoets, J. W. Langston, Barry J. Snow, J Tetrud, Michael Schulzer, D. B. Calne
Publikováno v:
Annals of neurology. 36(5)
Transient exposure to the toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) produces a syndrome resembling idiopathic parkinsonism (IP). While IP inevitably progresses, the long-term evolution of MPTP-parkinsonism is unknown. Fluorodopa posit