Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Francois Hyafil"'
Autor:
Alain Claude-Marie Daugan, Francois Hyafil, Jorge Kirilovsky, Hervé Coste, Anne-Charlotte de Gouville, Cécile Ruault, Richard Frederic Labaudiniere, Pascal Grondin
Publikováno v:
Journal of Medicinal Chemistry. 46:4525-4532
Starting from ethyl beta-carboline-3-carboxylate (beta-CCE), 1, a modest inhibitor of type 5 phosphodiesterase (PDE5), a series of functionalized tetrahydro-beta-carboline derivatives has been identified as a novel chemical class of potent and select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefc764d9520b29015f394c2c2648146
https://doi.org/10.1021/jm030056e
https://doi.org/10.1021/jm030056e
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acd0c36fa53a7fa65e1553a9c7f2bcbf
https://doi.org/10.1002/chin.199549107
https://doi.org/10.1002/chin.199549107
Publikováno v:
Blood. 78:2027-2035
Tissue factor (TF) is the first factor of the extrinsic pathway of coagulation. Normally, TF is not expressed on the surface of endothelial cells. However, expression of TF can be induced in these cells in response to stimulation by diverse inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1e55862923d684214f6833b671bd59
https://doi.org/10.1182/blood.v78.8.2027.bloodjournal7882027
https://doi.org/10.1182/blood.v78.8.2027.bloodjournal7882027
Autor:
Anne-Charlotte de Gouville, Pascal Grondin, Cécile Ruault, Jean Michel Linget, Francois Hyafil, Richard Frederic Labaudiniere, Alain Claude-Marie Daugan, Jorge Kirilovsky, Hervé Coste
Publikováno v:
Journal of medicinal chemistry. 46(21)
Modification of the hydantoin ring in the previously described lead compound 2a has led to the discovery of compound 12a, tadalafil, a highly potent and highly selective PDE5 inhibitor. The replacement of the hydantoin in compound 2a by a piperazined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7f3a8a7236df75151a560bbf5d9d73
https://pubmed.ncbi.nlm.nih.gov/14521415
https://pubmed.ncbi.nlm.nih.gov/14521415
Publikováno v:
Peptides 1994 ISBN: 9789072199218
Peptides 1994
Peptides 1994
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae5df1e966f81ecd94fb46ee31fd4d9d
https://doi.org/10.1007/978-94-011-1468-4_204
https://doi.org/10.1007/978-94-011-1468-4_204
Autor:
Dominique Belin, Nathalie Busso, Christophe Chesne, Edwige Nicodeme, André Guillouzo, Francois Hyafil
Publikováno v:
Hepatology, Vol. 20, No 1 Pt 1 (1994) pp. 186-190
We examined the effects of inflammatory cytokines (interleukin-1 beta, tumor necrosis factor-alpha and transforming growth factor-beta) on the plasminogen activator system (urokinase, tissue-type plasminogen activator, type 1 plasminogen activator in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95130ef1e41ab9735b8fb527758e7779
https://archive-ouverte.unige.ch/unige:10871
https://archive-ouverte.unige.ch/unige:10871
Publikováno v:
Journal of the American Chemical Society. 117:5405-5406
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da5d340ddf3d730cc6dc42826bcc40a5
https://doi.org/10.1021/ja00124a042
https://doi.org/10.1021/ja00124a042
Autor:
Jack L. Strominger, Francois Hyafil
Publikováno v:
Proceedings of the National Academy of Sciences. 76:5834-5838
Human histocompatibility antigens HLA-A, HLA-B, and HLA-C are a complex of two noncovalently associated subunits: a heavy chain glycoprotein (alpha) carrying the genetic polymorphism and an invariant light chain, beta 2-microglobulin (beta 2m). Upon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0569b8c8faf432f8486c15558c36ac
https://doi.org/10.1073/pnas.76.11.5834
https://doi.org/10.1073/pnas.76.11.5834
Publikováno v:
Scopus-Elsevier
A monoclonal antibody has allowed the characterization of various forms of uvomorulin, a glycoprotein involved in the process of compaction of mouse morula. In addition to various degradation products, uvomorulin exists as a 120-kilodalton exocellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001f7d074d5e9bc9c62f200f78a3f358
https://doi.org/10.1073/pnas.80.20.6274
https://doi.org/10.1073/pnas.80.20.6274
Publikováno v:
Cell. 21:927-934
Fab fragments of rabbit anti-embryonal carcinoma cells IgG dramatically perturb cell-cell interactions between embryonal carcinoma cells and between early mouse embryo blastomeres. These antibodies prevent compaction of preimplantation embryos (or tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4cba330c043685494d35a23c71d90c
https://doi.org/10.1016/0092-8674(80)90456-0
https://doi.org/10.1016/0092-8674(80)90456-0