Zobrazeno 1 - 1
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pro vyhledávání: '"Francois Guite-Vinet"'
Autor:
Matthias Majetschak, Joshua J. Ziarek, Youngshim Lee, Jonathan M. Eby, Sojin Shikano, Vadim Gaponenko, Xianlong Gao, Nikolaus Heveker, Ben Hitchinson, Hazem Abdelkarim, Brian F. Volkman, Nadya I. Tarasova, Yukari Okamoto, Francois Guite-Vinet
Publikováno v:
Science signaling. 11(552)
Repeated dosing of drugs targeting G protein-coupled receptors can stimulate antagonist tolerance, which reduces their efficacy; thus, strategies to avoid tolerance are needed. The efficacy of AMD3100, a competitive antagonist of the chemokine recept