Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Francois Fuks"'
Autor:
Raajit Rampal, Altuna Alkalin, Jozef Madzo, Aparna Vasanthakumar, Elodie Pronier, Jay Patel, Yushan Li, Jihae Ahn, Omar Abdel-Wahab, Alan Shih, Chao Lu, Patrick S. Ward, Jennifer J. Tsai, Todd Hricik, Valeria Tosello, Jacob E. Tallman, Xinyang Zhao, Danette Daniels, Qing Dai, Luisa Ciminio, Iannis Aifantis, Chuan He, Francois Fuks, Martin S. Tallman, Adolfo Ferrando, Stephen Nimer, Elisabeth Paietta, Craig B. Thompson, Jonathan D. Licht, Christopher E. Mason, Lucy A. Godley, Ari Melnick, Maria E. Figueroa, Ross L. Levine
Publikováno v:
Cell Reports, Vol 9, Iss 5, Pp 1841-1855 (2014)
Summary: Somatic mutations in IDH1/IDH2 and TET2 result in impaired TET2-mediated conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). The observation that WT1 inactivating mutations anticorrelate with TET2/IDH1/IDH2 mutations in a
Externí odkaz:
https://doaj.org/article/48202f3cd1ec4d1588d2780b05ad48c9
Autor:
Dragan Milenkovic, Wim Vanden Berghe, Céline Boby, Christine Leroux, Ken Declerck, Katarzyna Szarc vel Szic, Karen Heyninck, Kris Laukens, Martin Bizet, Matthieu Defrance, Sarah Dedeurwaerder, Emilie Calonne, Francois Fuks, Guy Haegeman, Guido R M M Haenen, Aalt Bast, Antje R Weseler
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95527 (2014)
In a recent intervention study, the daily supplementation with 200 mg monomeric and oligomeric flavanols (MOF) from grape seeds for 8 weeks revealed a vascular health benefit in male smokers. The objective of the present study was to determine the im
Externí odkaz:
https://doaj.org/article/66dc8ff740ab4f338d19887c8d8c09cb
Autor:
Wouter Bossuyt, Avedis Kazanjian, Natalie De Geest, Sofie Van Kelst, Gert De Hertogh, Karel Geboes, Greg P Boivin, Judith Luciani, Francois Fuks, Marinee Chuah, Thierry VandenDriessche, Peter Marynen, Jan Cools, Noah F Shroyer, Bassem A Hassan
Publikováno v:
PLoS Biology, Vol 7, Iss 2, p e39 (2009)
Colon cancer accounts for more than 10% of all cancer deaths annually. Our genetic evidence from Drosophila and previous in vitro studies of mammalian Atonal homolog 1 (Atoh1, also called Math1 or Hath1) suggest an anti-oncogenic function for the Ato
Externí odkaz:
https://doaj.org/article/fb9b56ff2e344a0b8af06bba6b4c590a
Autor:
Francois Fuks
This protocol describes how stable knockdown is performed using the pSUPER.retro.puro (pRS) lentiviral vector (OligoEngine) to form short hairpin RNAs for RNAi. Transient co-transfection of HEK293GP packaging cells is used to generate cell-free viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70e881901135131c861402241d7eda1b
https://doi.org/10.21203/rs.3.pex-1329/v1
https://doi.org/10.21203/rs.3.pex-1329/v1
Autor:
Xionghui Lin, Benjamin Swedlund, Mai-Linh N. Ton, Shila Ghazanfar, Carolina Guibentif, Catherine Paulissen, Elodie Baudelet, Elise Plaindoux, Younes Achouri, Emilie Calonne, Christine Dubois, William Mansfield, Stéphane Zaffran, John C. Marioni, Francois Fuks, Berthold Göttgens, Fabienne Lescroart, Cédric Blanpain
Publikováno v:
Nature Cell Biology
Nature Cell Biology, 2022, 24 (7), pp.1114-1128. ⟨10.1038/s41556-022-00947-3⟩
Nature Cell Biology, 2022, 24 (7), pp.1114-1128. ⟨10.1038/s41556-022-00947-3⟩
The mammalian heart arises from various populations of Mesp1-expressing cardiovascular progenitors (CPs) that are specified during the early stages of gastrulation. Mesp1 is a transcription factor that acts as a master regulator of CP specification a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290000607eadbc0a3f96b2949ab079e8
Autor:
Natalia Pinello, Renhua Song, Quintin Lee, Emilie Calonne, Mark Larance, François Fuks, Justin J. -L. Wong
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-15 (2024)
Abstract RNA modifications have emerged as central regulators of gene expression programs. Amongst RNA modifications are N6-methyladenosine (m6A) and RNA 5-hydroxymethylcytosine (5hmC). While m6A is established as a versatile regulator of RNA metabol
Externí odkaz:
https://doaj.org/article/30faa3a3601c4e5fa04ca189700846df
Autor:
Raghavendra G Mirmira, Silva Arslanian, Kieren J Mather, Decio L Eizirik, Carmella Evans-Molina, Appakalai N Balamurugan, Bobbie-Jo Webb-Robertson, Ezio Bonifacio, Anette-Gabriele Ziegler, Piero Marchetti, Marco Bugliani, Miriam Cnop, Francois Fuks, Martin Bizet, Mathieu Defrance, Emily K Sims, Jennifer B Nelson, Jamie L Felton, Jean-Valery Turatsinze, Sarah A. Tersey, Farooq Syed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::976d4729b4d6b6d58a110db38e0928ec
https://doi.org/10.37247/pagen2ed.2.2021.4
https://doi.org/10.37247/pagen2ed.2.2021.4
Autor:
Felicia Fei-Lei Chung, Sandra González Maldonado, Amelie Nemc, Liacine Bouaoun, Vincent Cahais, Cyrille Cuenin, Aurelie Salle, Theron Johnson, Bekir Ergüner, Marina Laplana, Paul Datlinger, Jana Jeschke, Elisabete Weiderpass, Vessela Kristensen, Suzette Delaloge, François Fuks, Angela Risch, Akram Ghantous, Christoph Plass, Christoph Bock, Rudolf Kaaks, Zdenko Herceg
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-10 (2023)
Abstract Background Epigenetic alterations are a near-universal feature of human malignancy and have been detected in malignant cells as well as in easily accessible specimens such as blood and urine. These findings offer promising applications in ca
Externí odkaz:
https://doaj.org/article/f3d701c524644d55890c75bac50f8463
Autor:
Badri Nath Singh, Hiep Tran, Joseph Kramer, Elmira Kirichenko, Neha Changela, Fei Wang, Yaping Feng, Dibyendu Kumar, Min Tu, Jie Lan, Martin Bizet, François Fuks, Ruth Steward
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0293894 (2024)
Modifications of mRNA, especially methylation of adenosine, have recently drawn much attention. The much rarer modification, 5-hydroxymethylation of cytosine (5hmC), is not well understood and is the subject of this study. Vertebrate Tet proteins are
Externí odkaz:
https://doaj.org/article/3ce50553810e4b2e8cb5a9fbd4184a4f