Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Francois Bordeleau"'
Autor:
Mylaine Breton, Isabelle Gaboury, Elisabeth Martin, Michael E. Green, Tara Kiran, Maude Laberge, Janusz Kaczorowski, Noah Ivers, Nadia Deville-Stoetzel, Francois Bordeleau, Christine Beaulieu, Sarah Descoteaux
Publikováno v:
BMC Primary Care, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Improving access to primary health care is among top priorities for many countries. Advanced Access (AA) is one of the most recommended models to improve timely access to care. Over the past 15 years, the AA model has been impleme
Externí odkaz:
https://doaj.org/article/74e67f7036bf46adb7f47c68e6462f46
Autor:
Wenjun Wang, Paul V. Taufalele, Martial Millet, Kevin Homsy, Kyra Smart, Emily D. Berestesky, Curtis T. Schunk, Matthew M. Rowe, Francois Bordeleau, Cynthia A. Reinhart-King
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112338- (2023)
Summary: During intravasation, cancer cells cross the endothelial barrier and enter the circulation. Extracellular matrix stiffening has been correlated with tumor metastatic potential; however, little is known about the effects of matrix stiffness o
Externí odkaz:
https://doaj.org/article/7fdc709fb6454d83b7c97e3b8661d0fc
Autor:
Samantha C Schwager, Katherine M Young, Lauren A Hapach, Caroline M Carlson, Jenna A Mosier, Tanner J McArdle, Wenjun Wang, Curtis Schunk, Anissa L Jayathilake, Madison E Bates, Francois Bordeleau, Marc A Antonyak, Richard A Cerione, Cynthia A Reinhart-King
Publikováno v:
eLife, Vol 11 (2022)
Cancer cell migration is highly heterogeneous, and the migratory capability of cancer cells is thought to be an indicator of metastatic potential. It is becoming clear that a cancer cell does not have to be inherently migratory to metastasize, with w
Externí odkaz:
https://doaj.org/article/622c88bf6fa14684a1a8c69fe64f0098
Autor:
Matthew R. Zanotelli, Aniqua Rahman-Zaman, Jacob A. VanderBurgh, Paul V. Taufalele, Aadhar Jain, David Erickson, Francois Bordeleau, Cynthia A. Reinhart-King
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Migrating cells tune their energy utilization in response to their microenvironment, but how cellular energetics direct navigation remains unclear. Here, the authors report that energetic costs for motility, regulated by cell mechanics and confinemen
Externí odkaz:
https://doaj.org/article/d89947d85d604810a3c24366f9f1743c
Autor:
Shaoqin Han, Jianyun Huang, Bingqian Liu, Bowen Xing, Francois Bordeleau, Cynthia A. Reinhart-King, Wenxin Li, J. Jillian Zhang, Xin-Yun Huang
Publikováno v:
Molecular Oncology, Vol 10, Iss 7, Pp 966-980 (2016)
Tumor metastasis is the major cause of mortality of cancer patients, being responsible for ∼90% of all cancer deaths. One of the key steps during tumor metastasis is tumor cell migration which requires actin cytoskeletal reorganization. Among the c
Externí odkaz:
https://doaj.org/article/3c6aa1559fc64dbe851d5e4d20f47ae8
Autor:
Joseph P. Miller, Brandon H. Borde, Francois Bordeleau, Matthew R. Zanotelli, Danielle J. LaValley, Dylan J. Parker, Lawrence J. Bonassar, Susan C. Pannullo, Cynthia A. Reinhart-King
Publikováno v:
APL Bioengineering, Vol 2, Iss 3, Pp 031901-031901-11 (2018)
Cells receive mechanical cues from their extracellular matrix (ECM), which direct migration, differentiation, apoptosis, and in some cases, the transition to a cancerous phenotype. As a result, there has been significant research to develop methods t
Externí odkaz:
https://doaj.org/article/223ef4ec142d441abf2b1ed6d41a7e83
Autor:
Matthew R. Zanotelli, Aniqua Rahman-Zaman, Jacob A. VanderBurgh, Paul V. Taufalele, Aadhar Jain, David Erickson, Francois Bordeleau, Cynthia A. Reinhart-King
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/06b0615186df433ca7d9cb4f9f4ab60f
Publikováno v:
Micromachines, Vol 10, Iss 6, p 418 (2019)
The tumor microenvironment (TME) is composed of dynamic and complex networks composed of matrix substrates, extracellular matrix (ECM), non-malignant cells, and tumor cells. The TME is in constant evolution during the disease progression, most notabl
Externí odkaz:
https://doaj.org/article/eed8591f0ab34c02b756d168e5da1a54
Publikováno v:
F1000Research, Vol 5 (2016)
There has been immense progress in our understanding of the factors driving cell migration in both two-dimensional and three-dimensional microenvironments over the years. However, it is becoming increasingly evident that even though most cells share
Externí odkaz:
https://doaj.org/article/a1b6963d478f478d9ffdce22f6e17dd0
Autor:
Marsha C Lampi, Courtney J Faber, John Huynh, Francois Bordeleau, Matthew R Zanotelli, Cynthia A Reinhart-King
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147033 (2016)
Arterial stiffening accompanies both aging and atherosclerosis, and age-related stiffening of the arterial intima increases RhoA activity and cell contractility contributing to increased endothelium permeability. Notably, statins are 3-hydroxy-3-meth
Externí odkaz:
https://doaj.org/article/17923a92fb884e909a621d63b453e267