Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Francois Balloux"'
Autor:
Ruobing Wang, Anru Zhang, Shijun Sun, Guankun Yin, Xingyu Wu, Qi Ding, Qi Wang, Fengning Chen, Shuyi Wang, Lucy van Dorp, Yawei Zhang, Longyang Jin, Xiaojuan Wang, Francois Balloux, Hui Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The acquisition of exogenous mobile genetic material imposes an adaptive burden on bacteria, whereas the adaptational evolution of virulence plasmids upon entry into carbapenem-resistant Klebsiella pneumoniae (CRKP) and its impact remains un
Externí odkaz:
https://doaj.org/article/18e8fdc680694d36a2e6e816a00e4569
Autor:
Cedric C. S. Tan, Jahcub Trew, Thomas P. Peacock, Kai Yi Mok, Charlie Hart, Kelvin Lau, Dongchun Ni, C. David L. Orme, Emma Ransome, William D. Pearse, Christopher M. Coleman, Dalan Bailey, Nazia Thakur, Jessica L. Quantrill, Ksenia Sukhova, Damien Richard, Laura Kahane, Guy Woodward, Thomas Bell, Lisa Worledge, Joe Nunez-Mino, Wendy Barclay, Lucy van Dorp, Francois Balloux, Vincent Savolainen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract There has been limited characterisation of bat-borne coronaviruses in Europe. Here, we screened for coronaviruses in 48 faecal samples from 16 of the 17 bat species breeding in the UK, collected through a bat rehabilitation and conservationi
Externí odkaz:
https://doaj.org/article/340c431a49ba426eafcb2fe573889dd8
Autor:
Martina Milighetti, Yanchun Peng, Cedric Tan, Michal Mark, Gayathri Nageswaran, Suzanne Byrne, Tahel Ronel, Tom Peacock, Andreas Mayer, Aneesh Chandran, Joshua Rosenheim, Matthew Whelan, Xuan Yao, Guihai Liu, Suet Ling Felce, Tao Dong, Alexander J. Mentzer, Julian C. Knight, Francois Balloux, Erez Greenstein, Shlomit Reich-Zeliger, Corinna Pade, Joseph M. Gibbons, Amanda Semper, Tim Brooks, Ashley Otter, Daniel M. Altmann, Rosemary J. Boyton, Mala K. Maini, Aine McKnight, Charlotte Manisty, Thomas A. Treibel, James C. Moon, Mahdad Noursadeghi, Benny Chain
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106937- (2023)
Summary: T cell responses precede antibody and may provide early control of infection. We analyzed the clonal basis of this rapid response following SARS-COV-2 infection. We applied T cell receptor (TCR) sequencing to define the trajectories of indiv
Externí odkaz:
https://doaj.org/article/a3d7eacf94e249aeb9cbbd5c5378f753
Autor:
Mislav Acman, Ruobing Wang, Lucy van Dorp, Liam P. Shaw, Qi Wang, Nina Luhmann, Yuyao Yin, Shijun Sun, Hongbin Chen, Hui Wang, Francois Balloux
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Gene bla NDM, conferring resistance to carbapenem antibiotics, is globally distributed across Gram-negative bacteria on multiple plasmids. Here, Acman et al. study the dynamics underlying bla NDM dissemination across over 6000 bacterial genomes, and
Externí odkaz:
https://doaj.org/article/cdbc6cf6d6af4b9b8a7bbe8440955e84
Autor:
Arturo Torres Ortiz, Jorge Coronel, Julia Rios Vidal, Cesar Bonilla, David A. J. Moore, Robert H. Gilman, Francois Balloux, Onn Min Kon, Xavier Didelot, Louis Grandjean
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Signals of antimicrobial resistance in pathogen genomes may be detectable before the organism evolves an antimicrobial resistance phenotype. Here, the authors investigate this hypothesis using Mycobacterium tuberculosis data from Peru and identify ca
Externí odkaz:
https://doaj.org/article/2ccdd8bfb5584496a56f3790c754b79f
Autor:
Hongbin Chen, Yuyao Yin, Lucy van Dorp, Liam P. Shaw, Hua Gao, Mislav Acman, Jizhen Yuan, Fengning Chen, Shijun Sun, Xiaojuan Wang, Shuguang Li, Yawei Zhang, Rhys A. Farrer, Hui Wang, Francois Balloux
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Abstract Background Methicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen subdivided into lineages termed sequence types (STs). Since the 1950s, successive waves of STs have appeared and replaced previously dominant lineag
Externí odkaz:
https://doaj.org/article/da1a9c64268c4ba6ab11603c6a35c130
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Plasmids can mediate the exchange of genetic material between bacterial cells. Here, Acman et al. use network analyses to study the population structure and dynamics of over 10,000 plasmids, assigning them into cliques that correlate with gene conten
Externí odkaz:
https://doaj.org/article/5e13566d5cc74ba48b60bd88110ec8bb
Autor:
Charlotte E. Ford, Lola M. Brookes, Emily Skelly, Chris Sergeant, Tresai Jordine, Francois Balloux, Richard A. Nichols, Trenton W. J. Garner
Publikováno v:
Viruses, Vol 14, Iss 12, p 2635 (2022)
Ranaviruses have been involved in amphibian mass mortality events worldwide. Effective screening to control this pathogen is essential; however, current sampling methods are unsuitable for the detection of subclinical infections. Non-lethal screening
Externí odkaz:
https://doaj.org/article/5e244cc8edf648909529c60ab5664ee1
Autor:
Camus Nimmo, Liam P. Shaw, Ronan Doyle, Rachel Williams, Kayleen Brien, Carrie Burgess, Judith Breuer, Francois Balloux, Alexander S. Pym
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Repeated culture reduces within-sample Mycobacterium tuberculosis genetic diversity due to selection of clones suited to growth in culture and/or random loss of lineages, but it is not known to what extent omitting the culture ste
Externí odkaz:
https://doaj.org/article/7f9ac5b530d149529c000208d18a3f50
Autor:
Rhys A. Farrer, Miwha Chang, Michael J. Davis, Lucy van Dorp, Dong-Hoon Yang, Terrance Shea, Thomas R. Sewell, Wieland Meyer, Francois Balloux, Hannah M. Edwards, Duncan Chanda, Geoffrey Kwenda, Mathieu Vanhove, Yun C. Chang, Christina A. Cuomo, Matthew C. Fisher, Kyung J. Kwon-Chung
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT We discovered a new lineage of the globally important fungal pathogen Cryptococcus gattii on the basis of analysis of six isolates collected from three locations spanning the Central Miombo Woodlands of Zambia, Africa. All isolates were from
Externí odkaz:
https://doaj.org/article/bcb77ff1bd024b81bbe6dd0516cb5c36