Antibody Repertoire Development in Fetal and Neonatal Piglets. XI. The Relationship of Variable Heavy Chain Gene Usage and the Genomic Organization of the Variable Heavy Chain Locus

Autor: Tomoko, Eguchi-Ogawa, Nancy, Wertz, Xiu-Zhu, Sun, Francois, Piumi, Francois, Puimi, Hirohide, Uenishi, Kevin, Wells, Patrick, Chardon, Gregory J, Tobin, John E, Butler

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2010, 184 (7), pp.3734-3742. ⟨10.4049/jimmunol.0903616⟩
Journal of Immunology, 2010, 184 (7), pp.3734-3742. ⟨10.4049/jimmunol.0903616⟩

In this study, we have mapped the 3′ H chain V region (VH) genes and those in the H chain diversity, H chain joining, and 5′ portion of the H chain constant locus. We show that swine possess only two functional H chain diversity segments and only

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4080129db33433dd8a8ebd1879b8ae0
https://doi.org/10.4049/jimmunol.0903616