Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Franco Torrente"'
Autor:
Camilla Salvestrini, Mark Lucas, Paolo Lionetti, Franco Torrente, Sean James, Alan D Phillips, Simon H Murch
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106005 (2014)
We studied the expression of sulphated glycosaminoglycans (GAGs) in coeliac disease (CD) mucosa, as they are critical determinants of tissue volume, which increases in active disease. We also examined mucosal expression of IL-6, which stimulates exce
Externí odkaz:
https://doaj.org/article/ff2704730f1b43a3b056f1c4f04fae32
Autor:
Matthias Zilbauer, Andreas Jenke, Gundula Wenzel, Jan Postberg, Andreas Heusch, Alan D Phillips, Gabriele Noble-Jamieson, Franco Torrente, Camilla Salvestrini, Robert Heuschkel, Stefan Wirth
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e15389 (2010)
BACKGROUND: Human beta-defensins (hBDs) are antimicrobial peptides known to play a major role in intestinal innate host defence. Altered mucosal expression of hBDs has been suggested to be implicated in chronic inflammatory bowel disease pathogenesis
Externí odkaz:
https://doaj.org/article/a761b8a0233444ee9f67fafbf9b21330
Autor:
Franco Torrente, Susanna Meade, Eric I Benchimol, Lissy de Ridder, Nicholas M Croft, Jochen Kammermeier, David R Mack, Renz C W Klomberg, Dan Turner, David C Wilson, Javier Martín-de-Carpi, Jiri Bronsky, Jorge Amil Dias, Gregor Walker, C Heleen van Ommen, Michael P Powar, Natasha Burgess, Peter M Irving, Mark A Samaan, Richard Hansen
Publikováno v:
Journal of Crohn's & colitis, 16(10), 1609-1616. Oxford University Press
JOURNAL OF CROHNS & COLITIS
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
JOURNAL OF CROHNS & COLITIS
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Background and Aims Thromboprophylaxis use in paediatric inflammatory bowel disease [IBD] is inconsistent. Current guidelines only support treating children with acute severe colitis with risk factors. We convened an international RAND panel to explo
Culture Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids
Autor:
Rachel D Edgar, Francesca Perrone, April R Foster, Felicity Payne, Sophia Lewis, Komal M Nayak, Judith Kraiczy, Aurélie Cenier, Franco Torrente, Camilla Salvestrini, Robert Heuschkel, Kai O Hensel, Rebecca Harris, D. Leanne Jones, Daniel R Zerbino, Matthias Zilbauer
Background & AimsHuman intestinal epithelial organoids (IEO) are a powerful tool to model major aspects of intestinal development, health and diseases, as patient derived cultures retain many features found in-vivo. A necessary aspect of the organoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c70d852eae9f9e5b1e0975ac83948df8
https://doi.org/10.1101/2022.04.25.489354
https://doi.org/10.1101/2022.04.25.489354
Culture-Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids
Autor:
Rachel D. Edgar, Francesca Perrone, April R. Foster, Felicity Payne, Sophia Lewis, Komal M. Nayak, Judith Kraiczy, Aurélie Cenier, Franco Torrente, Camilla Salvestrini, Robert Heuschkel, Kai O. Hensel, Rebecca Harris, D. Leanne Jones, Daniel R. Zerbino, Matthias Zilbauer
Publikováno v:
Cellular and molecular gastroenterology and hepatology. 14(6)
BACKGROUND & AIMS: Human intestinal epithelial organoids (IEOs) are a powerful tool to model major aspects of intestinal development, health, and diseases because patient-derived cultures retain many features found in vivo. A necessary aspect of the
Autor:
Franco Torrente, Richard Hansen
Publikováno v:
Journal of Crohn's and Colitis. 16:691-692
Autor:
Nicholas A Kennedy, Graham A Heap, Harry D Green, Benjamin Hamilton, Claire Bewshea, Gareth J Walker, Amanda Thomas, Rachel Nice, Mandy H Perry, Sonia Bouri, Neil Chanchlani, Neel M Heerasing, Peter Hendy, Simeng Lin, Daniel R Gaya, J R Fraser Cummings, Christian P Selinger, Charlie W Lees, Ailsa L Hart, Miles Parkes, Shaji Sebastian, John C Mansfield, Peter M Irving, James Lindsay, Richard K Russell, Timothy J McDonald, Dermot McGovern, James R Goodhand, Tariq Ahmad, Vinod Patel, Zia Mazhar, Rebecca Saich, Ben Colleypriest, Tony C Tham, Tariq H Iqbal, Vishal Kaushik, Senthil Murugesan, Salil Singh, Sean Weaver, Cathryn Preston, Assad Butt, Melissa Smith, Dharamveer Basude, Amanda Beale, Sarah Langlands, Natalie Direkze, Franco Torrente, Juan De La Revella Negro, Chris Ewen MacDonald, Stephen M Evans, Anton V J Gunasekera, Alka Thakur, David Elphick, Achuth Shenoy, Chuka U Nwokolo, Anjan Dhar, Andrew T Cole, Anurag Agrawal, Stephen Bridger, Julie Doherty, Sheldon C Cooper, Shanika de Silva, Craig Mowat, Phillip Mayhead, Charlie Lees, Gareth Jones, James W Hart, Lisa Gervais, Paul Dunckley, Tariq Mahmood, Paul J R Banim, Sunil Sonwalkar, Deb Ghosh, Rosemary H Phillips, Amer Azaz, Richard Shenderey, Lawrence Armstrong, Claire Bell, Radhakrishnan Hariraj, Helen Matthews, Hasnain Jafferbhoy, Veena Zamvar, John S De Caestecker, Anne Willmott, Richard Miller, Palani Sathish Babu, Christos Tzivinikos, Stuart L Bloom, Guy Chung-Faye, Nicholas M Croft, John ME Fell, Marcus Harbord, Ailsa Hart, Ben Hope, James O Lindsay, Joel E Mawdsley, Alistair McNair, Kevin J Monahan, Charles D Murray, Timothy Orchard, Thankam Paul, Richard Pollok, Neil Shah, Matt W Johnson, Anita Modi, Kasamu Dawa Kabiru, B K Baburajan, Bim Bhaduri, Andrew Adebayo Fagbemi, Scott Levison, Jimmy K Limdi, Gill Watts, Stephen Foley, Arvind Ramadas, George MacFaul, John Mansfield, Leonie Grellier, Mary-Anne Morris, Mark Tremelling, Chris Hawkey, Sian Kirkham, Charles PJ Charlton, Astor Rodrigues, Alison Simmons, Stephen J Lewis, Jonathon Snook, Mark Tighe, Patrick M Goggin, Aminda N De Silva, Simon Lal, Mark S Smith, Simon Panter, Suranga Dharmisari, Martyn Carter, David Watts, Zahid Mahmood, Bruce McLain, Sandip Sen, Anna J Pigott, David Hobday, Emma Wesley, Richard Johnston, Cathryn Edwards, John Beckly, Deven Vani, Subramaniam Ramakrishnan, Rakesh Chaudhary, Nigel J Trudgill, Rachel Cooney, Andy Bell, Neeraj Prasad, John N Gordon, Matthew J Brookes, Andy Li, Stephen Gore
Publikováno v:
The Lancet Gastroenterology & Hepatology. 4:341-353
BACKGROUND: Anti-TNF drugs are effective treatments for the management of Crohn's disease but treatment failure is common. We aimed to identify clinical and pharmacokinetic factors that predict primary non-response at week 14 after starting treatment
Autor:
Fiona Cameron, Rachel Tayler, Janis Maginnis, Jenny Epstein, Jochen Kammermeier, Protima Deb, James J. Ashton, Veena Zamvar, Hemant S. Bhavsar, Maureen Lawson, David Devadason, David C. Wilson, Andrew Fagbemi, Lucy Howarth, Franco Torrente, Fevronia Kiparissi, R Mark Beattie, Rafeeq Muhammed, Thankam Paul, Priya Narula, Christine Spray
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition.
OBJECTIVES: Patients with paediatric inflammatory bowel disease (IBD) constitute one of the largest cohorts requiring transition from paediatric to adult services. Standardised transition care improves short and long-term patient outcomes. This study
Autor:
Judith Kraiczy, Matthias Zilbauer, Franco Torrente, Marco Gasparetto, Robert Heuschkel, Yosef Philip-McKenzie, Jack Satsangi, Nicholas T. Ventham, Felicity Payne, Claire Glemas, Daniel R. Zerbino, Rachel D. Edgar, Alexander Ross, Camilla Salvestrini, Rahul Kalla, Komal Nayak, Peter Sarkies
Publikováno v:
Gastroenterology
Background & Aims Gene expression patterns of CD8+ T cells have been reported to correlate with clinical outcomes of adults with inflammatory bowel diseases (IBD). We aimed at validating these findings in independent patient cohorts. Methods We obtai
Autor:
Jenny Epstein, Maureen Lawson, David Devadason, Franco Torrente, Richard Hansen, Veena Zamvar, Robert Mark Beattie, Lucy Howarth, James J. Ashton, Ahmed Kadir, Rafeeq Muhammed, Jochen Kammermeier, Protima Deb, Priya Narula, Richard K Russell, Elizabeth Renji, Fevronia Kiparissi, Christine Spray, Ben Hope, Hemant S. Bhavsar, Thankam Paul
Publikováno v:
Archives of Disease in Childhood
BackgroundCOVID-19 has impacted on healthcare provision. Anecdotally, investigations for children with inflammatory bowel disease (IBD) have been restricted, resulting in diagnosis with no histological confirmation and potential secondary morbidity.