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Optimization of G‐Quadruplex Ligands through a SAR Study Combining Parallel Synthesis and Screening of Cationic Bis(acylhydrazones).

Autor: Reznichenko, Oksana, Leclercq, Denis, Franco Pinto, Jaime, Mouawad, Liliane, Gabelica, Valérie, Granzhan, Anton

Publikováno v: Chemistry - A European Journal; 1/18/2023, Vol. 29 Issue 4, p1-15, 15p

Stratégies d'inhibition de la O⁶-méthylguanine-ADN-méthyltransférase (MGMT) pour la chimiothérapie combinée des gliomes résistants au témozolomide

Autor: Franco Pinto, Jaime

Glioma is the term coined for describing a vast group of primary cancers in the Central NervousSystem (CNS), whitin this group, we can find glioblastoma or glioblastoma multiforme (GBM) as the source of 60% of brain cancer in adults, having a peak in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______166::aa188f133f35b26abde85656d53e212b
https://theses.hal.science/tel-03565755

Harnessing an emissive guanine surrogate to design small-molecule fluorescent chemosensors of O⁶-methylguanine-DNA-methyltransferase (MGMT).

Autor: Fillion, Alexandra, Franco Pinto, Jaime, Granzhan, Anton

Publikováno v: Organic & Biomolecular Chemistry; 3/7/2022, Vol. 20 Issue 9, p1888-1892, 5p

Optimization of G-Quadruplex Ligands through a SAR Study Combining Parallel Synthesis and Screening of Cationic Bis(acylhydrazones).

Autor: Reznichenko O; CMBC, CNRS UMR9187, Inserm U1196, Institut Curie, PSL Research University, 91405, Orsay, France.; CMBC, CNRS UMR9187, Inserm U1196, Université Paris Saclay, 91405, Orsay, France., Leclercq D; CMBC, CNRS UMR9187, Inserm U1196, Institut Curie, PSL Research University, 91405, Orsay, France.; CMBC, CNRS UMR9187, Inserm U1196, Université Paris Saclay, 91405, Orsay, France., Franco Pinto J; CMBC, CNRS UMR9187, Inserm U1196, Institut Curie, PSL Research University, 91405, Orsay, France.; CMBC, CNRS UMR9187, Inserm U1196, Université Paris Saclay, 91405, Orsay, France., Mouawad L; CMBC, CNRS UMR9187, Inserm U1196, Institut Curie, PSL Research University, 91405, Orsay, France.; CMBC, CNRS UMR9187, Inserm U1196, Université Paris Saclay, 91405, Orsay, France., Gabelica V; Univ. Bordeaux, CNRS, INSERM, ARNA, UMR 5320, U1212, IECB, 33600, Pessac, France., Granzhan A; CMBC, CNRS UMR9187, Inserm U1196, Institut Curie, PSL Research University, 91405, Orsay, France.; CMBC, CNRS UMR9187, Inserm U1196, Université Paris Saclay, 91405, Orsay, France.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2023 Jan 18; Vol. 29 (4), pp. e202202427. Date of Electronic Publication: 2022 Nov 30.