Conserved 5-methyluridine tRNA modification modulates ribosome translocation.

Autor: Jones JD; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Franco MK; Program in Chemical Biology, University of Michigan, Ann Arbor, MI 48109., Giles RN; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Eyler DE; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Tardu M; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Smith TJ; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Snyder LR; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Polikanov YS; Department of Biological Sciences, University of Illinois, Chicago, IL 60607., Kennedy RT; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Niederer RO; Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109., Koutmou KS; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109.; Program in Chemical Biology, University of Michigan, Ann Arbor, MI 48109.; Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Aug 27; Vol. 121 (35), pp. e2401743121. Date of Electronic Publication: 2024 Aug 19.

Methylated guanosine and uridine modifications in S. cerevisiae mRNAs modulate translation elongation.

Autor: Jones JD; Department of Chemistry, University of Michigan, 930 N University Ann Arbor MI 48109 USA kkoutmou@umich.edu +1-734-764-5650., Franco MK; Program in Chemical Biology, University of Michigan, 930 N University Ann Arbor MI 48109 USA., Smith TJ; Department of Chemistry, University of Michigan, 930 N University Ann Arbor MI 48109 USA kkoutmou@umich.edu +1-734-764-5650., Snyder LR; Department of Chemistry, University of Michigan, 930 N University Ann Arbor MI 48109 USA kkoutmou@umich.edu +1-734-764-5650., Anders AG; Department of Chemistry, University of Michigan, 930 N University Ann Arbor MI 48109 USA kkoutmou@umich.edu +1-734-764-5650., Ruotolo BT; Department of Chemistry, University of Michigan, 930 N University Ann Arbor MI 48109 USA kkoutmou@umich.edu +1-734-764-5650., Kennedy RT; Department of Chemistry, University of Michigan, 930 N University Ann Arbor MI 48109 USA kkoutmou@umich.edu +1-734-764-5650.; Program in Chemical Biology, University of Michigan, 930 N University Ann Arbor MI 48109 USA., Koutmou KS; Department of Chemistry, University of Michigan, 930 N University Ann Arbor MI 48109 USA kkoutmou@umich.edu +1-734-764-5650.; Program in Chemical Biology, University of Michigan, 930 N University Ann Arbor MI 48109 USA.

Publikováno v: RSC chemical biology [RSC Chem Biol] 2023 Feb 20; Vol. 4 (5), pp. 363-378. Date of Electronic Publication: 2023 Feb 20 (Print Publication: 2023).

Pseudouridine synthase 7 is an opportunistic enzyme that binds and modifies substrates with diverse sequences and structures.

Autor: Purchal MK; Program in Chemical Biology, University of Michigan, Ann Arbor, MI 48109., Eyler DE; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Tardu M; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Franco MK; Program in Chemical Biology, University of Michigan, Ann Arbor, MI 48109., Korn MM; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Khan T; Program in Chemical Biology, University of Michigan, Ann Arbor, MI 48109., McNassor R; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Giles R; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Lev K; Program in Chemical Biology, University of Michigan, Ann Arbor, MI 48109., Sharma H; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Monroe J; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109., Mallik L; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109.; Department of Biophysics, University of Michigan, Ann Arbor, MI 48109., Koutmos M; Program in Chemical Biology, University of Michigan, Ann Arbor, MI 48109; mkoutmos@umich.edu kkoutmou@umich.edu.; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109.; Department of Biophysics, University of Michigan, Ann Arbor, MI 48109., Koutmou KS; Program in Chemical Biology, University of Michigan, Ann Arbor, MI 48109; mkoutmos@umich.edu kkoutmou@umich.edu.; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Jan 25; Vol. 119 (4).

Implications of RNA pseudouridylation for cancer biology and therapeutics: a narrative review.

Autor: Ding, Hanyi^1,2 (AUTHOR), Liu, Na^3,4 (AUTHOR), Wang, Yan^1,3 (AUTHOR), Adam, Sofia Abdulkadir³ (AUTHOR), Jin, Jie^1,3,5 (AUTHOR) jiej0503@zju.edu.cn, Feng, Weiying² (AUTHOR) fengweiying1997@126.com, Sun, Jie^1,3,5 (AUTHOR) sunjiehm@zju.edu.cn

Publikováno v: Journal of Translational Medicine. 10/7/2024, Vol. 22 Issue 1, p1-14. 14p.

β-Aminobutyric acid promotes stress tolerance, physiological adjustments, as well as broad epigenetic changes at DNA and RNA nucleobases in field elms (Ulmus minor).

Autor: Hoenicka, Hans¹ (AUTHOR) h.hoenicka@thuenen.de, Bein, Susanne¹ (AUTHOR), Starczak, Marta² (AUTHOR), Graf, Wolfgang¹ (AUTHOR), Hanelt, Dieter³ (AUTHOR), Gackowski, Daniel² (AUTHOR)

Publikováno v: BMC Plant Biology. 8/15/2024, Vol. 24 Issue 1, p1-15. 15p.