Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Franco L Lombino"'
Autor:
André T Lopes, Torben J Hausrat, Frank F Heisler, Kira V Gromova, Franco L Lombino, Timo Fischer, Laura Ruschkies, Petra Breiden, Edda Thies, Irm Hermans-Borgmeyer, Michaela Schweizer, Jürgen R Schwarz, Christian Lohr, Matthias Kneussel
Publikováno v:
PLoS Biology, Vol 18, Iss 8, p e3000820 (2020)
Mutations in the gene encoding the microtubule-severing protein spastin (spastic paraplegia 4 [SPG4]) cause hereditary spastic paraplegia (HSP), associated with neurodegeneration, spasticity, and motor impairment. Complicated forms (complicated HSP [
Externí odkaz:
https://doaj.org/article/fd94a10cc9314b0d9d95e7c1e309a73e
Autor:
Daniele Stajano, Franco L. Lombino, Michaela Schweizer, Markus Glatzel, Paul Saftig, Kira V. Gromova, Matthias Kneussel
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 9, Pp n/a-n/a (2023)
Abstract Neurons in the central nervous system release extracellular vesicles (EVs) and exosomes in response to synaptic activity to regulate physiological processes at target neurons. The intercellular transfer of proteins, mRNAs, lipids or metaboli
Externí odkaz:
https://doaj.org/article/5b642984c66640b5b1251b30ddfd3d80
Autor:
Wolfgang Wagner, Kristina Lippmann, Frank F. Heisler, Kira V. Gromova, Franco L. Lombino, Mona K. Roesler, Yvonne Pechmann, Sönke Hornig, Michaela Schweizer, Simona Polo, Jürgen R. Schwarz, Jens Eilers, Matthias Kneussel
Publikováno v:
Cell Reports, Vol 28, Iss 1, Pp 11-20.e9 (2019)
Summary: Myosin VI is an actin-based cytoskeletal motor implicated in various steps of membrane trafficking. Here, we investigated whether this myosin is crucial for synaptic function and plasticity in neurons. We find that myosin VI localizes at cer
Externí odkaz:
https://doaj.org/article/afe916e1b356400f8e150af47c713128
Autor:
Franco L. Lombino, Jürgen R. Schwarz, Yvonne Pechmann, Michaela Schweizer, Markus Glatzel, Christine E. Gee, Kira V. Gromova, Matthias Kneussel
Dynamic microtubules transiently polymerize into dendritic spines, however intracellular factors that regulate this process and their functional role at synapses are hardly understood. Using live imaging, electrophysiology, and glutamate uncaging, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dedb22389405d1511c2558f2ca8e6f77
https://doi.org/10.1101/2022.05.04.490623
https://doi.org/10.1101/2022.05.04.490623
Publikováno v:
Developmental Neurobiology. 81:333-350
Alpha- and beta-tubulin dimers polymerize into protofilaments that associate laterally to constitute a hollow tube, the microtubule. A dynamic network of interlinking filaments forms the microtubule cytoskeleton, which maintains the structure of cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083c0f8d0f432c3cd481538a2955f542
https://doi.org/10.1002/dneu.22745
https://doi.org/10.1002/dneu.22745
Autor:
Sabine A. H. Hoffmeister-Ullerich, Michael R. Kreutz, Laura Ruschkies, Jessica E. M. Dunleavy, Melanie Richter, Monika S. Brill, Thomas Misgeld, Franco L. Lombino, Edda Thies, Michael Frotscher, André T. Lopes, Torben J. Hausrat, David Lutz, Froylan Calderon de Anda, Mary Muhia, Francis J. McNally, Jeffrey Lopez-Rojas, Irm Hermans-Borgmeyer, Matthias Kneussel
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific reports, 9:15940
Scientific reports, vol 9, iss 1
Scientific Reports
Scientific reports, 9:15940
Scientific reports, vol 9, iss 1
Microtubule severing regulates cytoskeletal rearrangement underlying various cellular functions. Katanin, a heterodimer, consisting of catalytic (p60) and regulatory (p80) subunits severs dynamic microtubules to modulate several stages of cell divisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166efaa6b8e3f7367fa7a47152ee290b
http://link.springer.com/article/10.1038/s41598-019-52367-3
http://link.springer.com/article/10.1038/s41598-019-52367-3
Autor:
Frank F. Heisler, Franco L. Lombino, Mona Katrin Roesler, Matthias Kneussel, Jens Eilers, Kristina Lippmann, Michaela Schweizer, Wolfgang Wagner, Yvonne Pechmann, Kira V. Gromova, Jürgen R. Schwarz, Simona Polo, Sönke Hornig
Publikováno v:
Cell Reports, Vol 28, Iss 1, Pp 11-20.e9 (2019)
Summary: Myosin VI is an actin-based cytoskeletal motor implicated in various steps of membrane trafficking. Here, we investigated whether this myosin is crucial for synaptic function and plasticity in neurons. We find that myosin VI localizes at cer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f1b5a0250b91629baa3a6441f4d5c6
http://www.sciencedirect.com/science/article/pii/S2211124719307636
http://www.sciencedirect.com/science/article/pii/S2211124719307636
Publikováno v:
Developmental Neurobiology. 81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9077289c688ea55b255fb46f45c54060
https://doi.org/10.1002/dneu.22822
https://doi.org/10.1002/dneu.22822
Autor:
Jürgen R. Schwarz, Michaela Schweizer, Kira V. Gromova, Timo Fischer, Frank F. Heisler, Torben J. Hausrat, Franco L. Lombino, Christian Lohr, Irm Hermans-Borgmeyer, André T. Lopes, Petra Breiden, Edda Thies, Laura Ruschkies, Matthias Kneussel
Publikováno v:
PLoS Biology
PLoS Biology, Vol 18, Iss 8, p e3000820 (2020)
PLoS Biology, Vol 18, Iss 8, p e3000820 (2020)
Mutations in the gene encoding the microtubule-severing protein spastin (spastic paraplegia 4 [SPG4]) cause hereditary spastic paraplegia (HSP), associated with neurodegeneration, spasticity, and motor impairment. Complicated forms (complicated HSP [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9608091febc3d2e75111043496b5d754
https://doi.org/10.1371/journal.pbio.3000820
https://doi.org/10.1371/journal.pbio.3000820
Autor:
Giuseppe Frazzitta, Cristoforo Comi, Davide Uccellini, Michele Perini, Natalia Boveri, Gabriella Bertotti, Roberto Maestri, Giulio Riboldazzi, Sara Buttini, Maria Felice Ghilardi, Gianni Pezzoli, Marinella Turla, Franco L. Lombino
Publikováno v:
Neurorehabilitation and Neural Repair. 28:163-168
Background. Exercise may decrease the risk of Parkinson’s disease (PD) in humans and reduce PD symptoms in animal models. The beneficial effects have been linked to increased levels of neurotrophic factors. Objective. We examined whether intensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ab31004b9db02f7d4c9a01cf1c2b75
https://doi.org/10.1177/1545968313508474
https://doi.org/10.1177/1545968313508474