Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Franco Fortunato"'
Autor:
Jingyu An, Roma Kurilov, Teresa Peccerella, Frank Bergmann, Mouad Edderkaoui, Adrian Lim, Xu Zhou, Katrin Pfütze, Angela Schulz, Stephan Wolf, Kai Hu, Christoph Springfeld, Sadaf S. Mughal, Lenart Zezlina, Franco Fortunato, Georg Beyer, Julia Mayerle, Susanne Roth, Johannes Hulkkonen, Daniela Merz, Shigenori Ei, Arianeb Mehrabi, Martin Loos, Mohammed Al-Saeedi, Christoph W. Michalski, Markus W. Büchler, Thilo Hackert, Benedikt Brors, Stephen J. Pandol, Peter Bailey, John P. Neoptolemos
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102109- (2024)
Background: Despite some recent advances, pancreatic ductal adenocarcinoma (PDAC) remains a growing oncological challenge. New drugs capable of targeting more than one oncogenic pathway may be one way to improve patient outcomes. This study character
Externí odkaz:
https://doaj.org/article/df5a8e4d1fe7474090e2aa259e799323
Autor:
Cheng Chen, Shijin Wang, Linna Yu, Johannes Mueller, Franco Fortunato, Vanessa Rausch, Sebastian Mueller
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102081- (2021)
Background: Alcoholic liver disease (ALD) is the most common liver disease worldwide and its underlying molecular mechanisms are still poorly understood. Moreover, conflicting data have been reported on potentially protective autophagy, the exact rol
Externí odkaz:
https://doaj.org/article/84d3cea967204be1a378eff6c41f27eb
Autor:
Patrick Naumann, Jakob Liermann, Franco Fortunato, Thomas E Schmid, Klaus-Josef Weber, Jürgen Debus, Stephanie E Combs
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180940 (2017)
Sulforaphane (SFN), an herbal isothiocyanate enriched in cruciferous vegetables like broccoli and cauliflower, has gained popularity for its antitumor effects in cell lines such as pancreatic cancer. Antiproliferative as well as radiosensitizing prop
Externí odkaz:
https://doaj.org/article/770378d356454c9f996ed267b8c57efb
Publikováno v:
The Scientific World Journal, Vol 1, Pp 68-68 (2001)
Externí odkaz:
https://doaj.org/article/f1190b8f763c474d858c3669ea82df83
Autor:
Bin Yan, Li Liu, Lian Zhao, Ulf Hinz, Yiqiao Luo, Xuefeng An, Jury Gladkich, Carolina de la Torre, Zhenhua Huang, Daniel Schrapel, Wolfgang Gross, Franco Fortunato, Michael Schaefer, Matthias M Gaida, Ingrid Herr
Publikováno v:
Matrix Biology. 114:84-107
Several collagen subtypes are involved in pancreatic ductal adenocarcinoma (PDAC) desmoplasia, which constrains therapeutic efficacy. We evaluated collagen type VIII alpha 1 chain (COL8A1), whose function in PDAC is currently unknown. We identified C
Autor:
Milena Sachsenmaier, Markus W. Büchler, Ulla Klaiber, Frank Bergmann, John P. Neoptolemos, Thilo Hackert, Oliver Strobel, Franco Fortunato, Li Xie, Ulf Hinz, Leizhou Xia
Publikováno v:
Oncotarget
Background: The progression and response to systemic treatment of cancer is substantially dependent on the balance between cancer cell death (apoptosis and necroptosis) and cancer cell survival (autophagy). Although well characterized in experimental
Autor:
Xu Zhou, Roma Kurilov, John P. Neoptolemos, Benedikt Brors, Kai Hu, Teresa Peccerella, Jing-Yu An, Stephanie Roessler, Katrin Pfütze, Angela Schulz, Stephan Wolf, Nicolas Hohmann, Ulrike Heger, Oliver Strobel, Simon T Barry, Christoph Springfeld, Christine Tjaden, Frank Bergmann, Markus Büchler, Thilo Hackert, Franco Fortunato, Peter Bailey
Publikováno v:
Cancer Research. 82:A010-A010
The impact of neoadjuvant chemotherapy on tumor cells is largely unknown with resistance to therapy remaining a significant challenge. We analyzed 171 chemo-naïve and post-chemotherapy resected patient samples (chemoradiotherapy excluded) using RNAs
Autor:
Sebastian Mueller, Shijin Wang, Vanessa Rausch, Linna Yu, Johannes Mueller, Cheng Chen, Franco Fortunato
Publikováno v:
Redox Biology
Redox Biology, Vol 46, Iss, Pp 102081-(2021)
Redox Biology, Vol 46, Iss, Pp 102081-(2021)
Background Alcoholic liver disease (ALD) is the most common liver disease worldwide and its underlying molecular mechanisms are still poorly understood. Moreover, conflicting data have been reported on potentially protective autophagy, the exact role
Autor:
Franco Fortunato, Guido Kroemer, Z. Xu, M.W. Büchler, Frank Bergmann, L. Xia, Niels Grabe, John P. Neoptolemos, Thilo Hackert, X. Zhou
Publikováno v:
Cell Death & Disease
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2020, 11 (10), ⟨10.1038/s41419-020-03050-3⟩
Cell Death and Disease, Vol 11, Iss 10, Pp 1-15 (2020)
Cell Death and Disease, 2020, 11 (10), ⟨10.1038/s41419-020-03050-3⟩
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2020, 11 (10), ⟨10.1038/s41419-020-03050-3⟩
Cell Death and Disease, Vol 11, Iss 10, Pp 1-15 (2020)
Cell Death and Disease, 2020, 11 (10), ⟨10.1038/s41419-020-03050-3⟩
Chronic pancreatitis (CP) is associated with elevated plasma levels of bacterial lipopolysaccharide (LPS) and we have demonstrated reduced acinar cell autophagy in human CP tissue. Therefore, we investigated the role of autophagy in experimental endo
Autor:
Franco Fortunato, Kai Hu, Mouad Edderkaoui, Stephen J. Pandol, J. An, John P. Neoptolemos, M.W. Büchler, T. Hackert, Z. Xu
Publikováno v:
Pancreatology. 20:S126