Pharmacological potential of new metronidazole/eugenol/dihydroeugenol hybrids against Trypanosoma cruzi in vitro and in vivo

Autor: Gonçalves-Santos, Elda, Caldas, Ivo S., Fernandes, Valquiria Â., Franco, Lucas L., Pelozo, Mônica F., Feltrim, Fernando, Maciel, Juliana S., Machado, Jose Vaz C., Gonçalves, Reggiani V., Novaes, Rômulo D.

Publikováno v: In International Immunopharmacology August 2023 121

Synthesis and antimicrobial activity of molecular hybrids based on eugenol and chloramphenicol pharmacophores.

Autor: Oliveira, Lucas M., Siqueira, Fallon S., Silva, Michelle T., Machado, José V. C., Cordeiro, Cleydson F., Diniz, Lívia F., Campos, Marli M. A., Franco, Lucas L., Souza, Thiago B., Hawkes, Jamie A., Carvalho, Diogo T.

Publikováno v: Folia Microbiologica; Dec2023, Vol. 68 Issue 6, p823-833, 11p

SÍNTESE DE N-GLICOSILSULFONAMIDAS DERIVADAS DE D-GLICOSE E N-ACETILGLICOSAMINA

Autor: Franco, Lucas L., Brandão, Mário C., Filho, José D. S., Alves, Ricardo J.

Publikováno v: Química Nova, Vol 38, Iss 8, Pp 1044-1052 (2015)
Química Nova v.38 n.8 2015
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Química Nova, Volume: 38, Issue: 8, Pages: 1044-1052, Published: SEP 2015

Herein, we report the synthesis of β-N-glycosylsulfonamides derivatives of D-glucose and N-acetylglucosamine using conventional methods. We also describe a procedure that allows the preparation of these compounds in good yields without the anomeriza

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422015000801044&lng=en&tlng=en

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A New Straightforward Synthesis of 2', 3'-Didehydro-2', 3'-dideoxy-2'-(2'- (trimethylsilyl)ethylthio)thymidine, Key Intermediate for the Synthesis of 2'-Substituted Thionucleosides

Autor: Oliveira,Maralise P., Franco,Lucas L., Lima,Maria C. A., Simões,Cláudia M. O., Galdino,Suely L., Pitta,Ivan R., Décout,Jean-Luc, Alves,Ricardo J.

Publikováno v: Journal of the Brazilian Chemical Society, Volume: 26, Issue: 4, Pages: 816-821, Published: APR 2015
Journal of the Brazilian Chemical Society v.26 n.4 2015
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

We describe herein a straightforward and efficient preparation of 2',3'-dideoxy-2'-(2''- (trimethylsilyl)ethylthio)thymidine, which allows the preparation of diverse potentially antiviral and/or anticancer nucleosides (disulfides, thiols, sulfides, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b281670ab1cf5ef136314da9ad8ad0a6
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015000400816&lng=en&tlng=en