Zobrazeno 1 - 10
of 1 598
pro vyhledávání: '"Franco, Locatelli"'
Autor:
Matteo Cassandri, Antonella Porrazzo, Silvia Pomella, Beatrice Noce, Clemens Zwergel, Francesca Antonella Aiello, Francesca Vulcano, Luisa Milazzo, Simona Camero, Deborah Pajalunga, Massimo Spada, Valeria Manzi, Giovanni Luca Gravina, Silvia Codenotti, Michela Piccione, Miriam Tomaciello, Michele Signore, Giovanni Barillari, Cinzia Marchese, Alessandro Fanzani, Biagio De Angelis, Concetta Quintarelli, Christopher R. Vakoc, Eleanor Y. Chen, Francesca Megiorni, Franco Locatelli, Sergio Valente, Antonello Mai, Rossella Rota, Francesco Marampon
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-20 (2024)
Abstract Radiotherapy (RT) plays a critical role in the management of rhabdomyosarcoma (RMS), the prevalent soft tissue sarcoma in childhood. The high risk PAX3-FOXO1 fusion-positive subtype (FP-RMS) is often resistant to RT. We have recently demonst
Externí odkaz:
https://doaj.org/article/d2578a217b0d469480a398078bb622c7
Autor:
Giacomo Corleone, Cristina Sorino, Matteo Caforio, Stefano Di Giovenale, Francesca De Nicola, Frauke Goeman, Valentina Bertaina, Angela Pitisci, Clelia Cortile, Franco Locatelli, Valentina Folgiero, Maurizio Fanciulli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-19 (2024)
Abstract Background Enhancer reprogramming plays a significant role in the heterogeneity of cancer. However, we have limited knowledge about the impact of chromatin remodeling in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) patients, and h
Externí odkaz:
https://doaj.org/article/e6a90fbd8fa04cd28df478d56fad768a
Autor:
Daniela Cesana, Maria Pia Cicalese, Andrea Calabria, Pietro Merli, Roberta Caruso, Monica Volpin, Laura Rudilosso, Maddalena Migliavacca, Federica Barzaghi, Claudia Fossati, Francesco Gazzo, Simone Pizzi, Andrea Ciolfi, Alessandro Bruselles, Francesca Tucci, Giulio Spinozzi, Giulia Pais, Fabrizio Benedicenti, Matteo Barcella, Ivan Merelli, Pierangela Gallina, Stefania Giannelli, Francesca Dionisio, Serena Scala, Miriam Casiraghi, Luisa Strocchio, Luciana Vinti, Lucia Pacillo, Eleonora Draghi, Marcella Cesana, Sara Riccardo, Chiara Colantuono, Emmanuelle Six, Marina Cavazzana, Filippo Carlucci, Manfred Schmidt, Caterina Cancrini, Fabio Ciceri, Luca Vago, Davide Cacchiarelli, Bernhard Gentner, Luigi Naldini, Marco Tartaglia, Eugenio Montini, Franco Locatelli, Alessandro Aiuti
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Hematopoietic stem cell gene therapy (GT) using a γ-retroviral vector (γ-RV) is an effective treatment for Severe Combined Immunodeficiency due to Adenosine Deaminase deficiency. Here, we describe a case of GT-related T-cell acute lymphobl
Externí odkaz:
https://doaj.org/article/319bd86d084c40b6be16ee73e0b5af1a
Autor:
Lucia Pedace, Simone Pizzi, Luana Abballe, Maria Vinci, Celeste Antonacci, Sara Patrizi, Claudia Nardini, Francesca Del Bufalo, Sabrina Rossi, Giulia Pericoli, Francesca Gianno, Zein Mersini Besharat, Luca Tiberi, Angela Mastronuzzi, Elisabetta Ferretti, Marco Tartaglia, Franco Locatelli, Andrea Ciolfi, Evelina Miele
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract In vitro models of pediatric brain tumors (pBT) are instrumental for better understanding the mechanisms contributing to oncogenesis and testing new therapies; thus, ideally, they should recapitulate the original tumor. We applied DNA methyl
Externí odkaz:
https://doaj.org/article/3e271e6514f4435baadb82be0810cbf5
Autor:
Christina Peters, Angela Bruno, Carmelo Rizzari, Alessandra Brescianini, Arend von Stackelberg, Christin Linderkamp, Yi Zeng, Gerhard Zugmaier, Franco Locatelli
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/062c74855005439c9f06bcb9650d574f
Autor:
Sara Patrizi, Silvia Vallese, Lucia Pedace, Claudia Nardini, Alessandra Stracuzzi, Sabina Barresi, Isabella Giovannoni, Luana Abballe, Celeste Antonacci, Ida Russo, Angela Di Giannatale, Rita Alaggio, Franco Locatelli, Giuseppe Maria Milano, Evelina Miele
Publikováno v:
Frontiers in Epigenetics and Epigenomics, Vol 2 (2024)
Ewing Sarcomas (EWS, OMIM#612219) presents a major challenge in pediatric oncology due to its aggressive nature and poor prognosis, particularly in metastatic cases. Genetic fusions involving the EWSR1 gene and ETS family transcription factors are co
Externí odkaz:
https://doaj.org/article/de3250e704584142bb010d7d8c5ba878
Autor:
Angela Mastronuzzi, Rita Carsetti, Maria Antonietta De Ioris, Chiara Agrati, Giada Del Baldo, Cristina Russo, Maria Giuseppina Cefalo, Pietro Merli, Carlo Federico Perno, Vito Andrea dell'Anna, Annalisa Serra, Veronica Bordoni, Eva Piano Mortari, Valentina Marcellini, Christian Albano, Giulia Linardos, Valentino Costabile, Matilde Sinibaldi, Marika Guercio, Stefano di Cecca, Concetta Quintarelli, Franco Locatelli
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34503- (2024)
Immunocompromised children are at risk of developing severe COVID-19 infection. We conducted a pilot prospective study to evaluate the impact of cancer treatment and stem cell transplantation on immunogenicity of two doses of BNT162b2 vaccine in pedi
Externí odkaz:
https://doaj.org/article/b4ccc5b9eef748c8bf7b9a17079caa56
Autor:
Roberto Rondelli, Tamara Belotti, Riccardo Masetti, Franco Locatelli, Maura Massimino, Alessandra Biffi, Carlo Dufour, Franca Fagioli, Giuseppe Menna, Andrea Biondi, Claudio Favre, Marco Zecca, Nicola Santoro, Giovanna Russo, Silverio Perrotta, Andrea Pession, Arcangelo Prete
Publikováno v:
Italian Journal of Pediatrics, Vol 50, Iss 1, Pp 1-9 (2024)
Abstract Background In Italy, there is a network of centres headed by the Italian Association of Pediatric Hematology and Oncology (AIEOP) for the diagnosis and treatment of paediatric cancers on almost the entire national territory. Nevertheless, mi
Externí odkaz:
https://doaj.org/article/187b8f29096d4a3dad2c8ddcafe11c1e
Autor:
Sara Patrizi, Evelina Miele, Lorenza Falcone, Silvia Vallese, Sabrina Rossi, Sabina Barresi, Isabella Giovannoni, Lucia Pedace, Claudia Nardini, Ilaria Masier, Luana Abballe, Antonella Cacchione, Ida Russo, Angela Di Giannatale, Valentina Di Ruscio, Claudia Maria Salgado, Angela Mastronuzzi, Andrea Ciolfi, Marco Tartaglia, Giuseppe Maria Milano, Franco Locatelli, Rita Alaggio
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Malignant peripheral nerve sheath tumors (MPNSTs) account for 3–10% of pediatric sarcomas, 50% of which occur in neurofibromatosis type 1 (NF1). Sporadic MPNSTs diagnosis may be challenging due to the absence of specific markers
Externí odkaz:
https://doaj.org/article/e153def98c9c43fea6e3e57bc6160250
Autor:
Federica Galaverna, Sara Flamini, Carmen Dolores De Luca, Ilaria Pili, Emilia Boccieri, Francesca Benini, Francesco Quagliarella, Chiara Rosignoli, Marco Rosichini, Shirley Genah, Marialuigia Catanoso, Antonella Cardinale, Gabriele Volpe, Marianna Coccetti, Angela Pitisci, Giuseppina Li Pira, Roberto Carta, Barbarella Lucarelli, Francesca Del Bufalo, Valentina Bertaina, Marco Becilli, Daria Pagliara, Mattia Algeri, Pietro Merli, Franco Locatelli, Enrico Velardi
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Mucosal-associated invariant T (MAIT) cells are innate-like T-cells implicated in the response to fungal and bacterial infections. Their contribution to restoring T-cell immunity and influencing hematopoietic stem cell transplant (HSCT) outcomes rema
Externí odkaz:
https://doaj.org/article/25f2a926a6bd46bd88584bb02e4a9e44